Employment generation in rural Africa : mid-term results from an experimental evaluation of the Youth Opportunities Program in Northern Uganda

Can cash transfers promote employment and reduce poverty in rural Africa? Will lower youth unemployment and poverty reduce the risk of social instability? The authors experimentally evaluate one of Uganda's largest development programs, which provided thousands of young people nearly unconditional, unsupervised cash transfers to pay for vocational training, tools, and business start-up costs. Mid-term results after two years suggest four main findings. First, despite a lack of central monitoring and accountability, most youth invest the transfer in vocational skills and tools. Second, the economic impacts of the transfer are large: hours of non-household employment double and cash earnings increase by nearly 50 percent relative to the control group. The authors estimate the transfer yields a real annual return on capital of 35 percent on average. Third, the evidence suggests that poor access to credit is a major reason youth cannot start these vocations in the absence of aid. Much of the heterogeneity in impacts is unexplained, however, and is unrelated to conventional economic measures of ability, suggesting we have much to learn about the determinants of entrepreneurship. Finally, these economic gains result in modest improvements in social stability. Measures of social cohesion and community support improve mildly, by roughly 5 to 10 percent, especially among males, most likely because the youth becomes a net giver rather than a net taker in his kin and community network. Most strikingly, we see a 50 percent fall in interpersonal aggression and disputes among males, but a 50 percent increase among females. Neither change seems related to economic performance nor does social cohesion a puzzle to be explored in the next phase of the study. These results suggest that increasing access to credit and capital could stimulate employment growth in rural Africa. In particular, unconditional and unsupervised cash transfers may be a more effective and cost-efficient forming of large-scale aid than commonly believed. A second stage of data collection in 2012 will collect longitudinal economic impacts, additional data on political violence and behavior, and explore alternative theoretical mechanisms.Debt Markets,Labor Policies,Economic Theory&Research,Primary Education,Educational Sciences

The transitioning process: A qualitative case study of international swimming and diving student-athletes competing in the NCAA

Prior studies examining international student-athletes’ transition experiences to life on American colleges campuses have generally focused on outcomes related to their recruiting experience and change adaptation. Few studies included the adjustment process and challenges faced by the individuals. The primary purpose of this case study was to add to the existing literature by expanding on the psychological transition process of international swimming and diving student-athletes experience after joining an American intercollegiate athletics team. Utilizing Bridges (1986) model, the present study employed semi-structured interviews amongst 10 international student-athletes from a large NCAA Division I university. A thematic analysis revealed seven major themes, which were: realization that change was necessary, reflecting on the decision, language barrier, education system, cultural adjustment and valuable lessons,international bond, and words of wisdom. The findings suggested transition is a multi-stage process that occurs throughout student-athletes’ experiences on campus.   Key words: college athletics, international student-athletes, transitioning proces

Connecting People: An Exploration of Building an Intranet through Autoethnography

This study examines the development and failure of an Intranet at a small company in Southern Illinois. Using autoethnographic methods, I analyzed the events surrounding the development and rejection of the Intranet by the organization\u27s president. Using Burke\u27s concepts of identification and mystery, I analyzed the relationship between the failure of the Intranet and the president\u27s reasoning for not supporting its development. Throughout this study I evaluate the lntranet\u27s development, the impact of other\u27s involvement, as well as the impact that the design of the layout could have on communication at the Company. I find that the failure to develop identification with others in a cooperative development environment could lead to failure of projects

Connecting People: An Exploration of Building an Intranet through Autoethnography

This study examines the development and failure of an Intranet at a small company in Southern Illinois. Using autoethnographic methods, I analyzed the events surrounding the development and rejection of the Intranet by the organization\u27s president. Using Burke\u27s concepts of identification and mystery, I analyzed the relationship between the failure of the Intranet and the president\u27s reasoning for not supporting its development. Throughout this study I evaluate the lntranet\u27s development, the impact of other\u27s involvement, as well as the impact that the design of the layout could have on communication at the Company. I find that the failure to develop identification with others in a cooperative development environment could lead to failure of projects

The ATPase cycle of PcrA helicase and its coupling to translocation on DNA.

The superfamily 1 bacterial helicase PcrA has a role in the replication of certain plasmids, acting with the initiator protein (RepD) that binds to and nicks the double-stranded origin of replication. PcrA also translocates single-stranded DNA with discrete steps of one base per ATP hydrolyzed. Individual rate constants have been determined for the DNA helicase PcrA ATPase cycle when bound to either single-stranded DNA or a double-stranded DNA junction that also has RepD bound. The fluorescent ATP analogue 2'(3')-O-(N-methylanthraniloyl)ATP was used throughout all experiments to provide a complete ATPase cycle for a single nucleotide species. Fluorescence intensity and anisotropy stopped-flow measurements were used to determine rate constants for binding and release. Quenched-flow measurements provided the kinetics of the hydrolytic cleavage step. The fluorescent phosphate sensor MDCC-PBP was used to measure phosphate release kinetics. The chemical cleavage step is the rate-limiting step in the cycle and is essentially irreversible and would result in the bound ATP complex being a major component at steady state. This cleavage step is greatly accelerated by bound DNA, producing the high activation of this protein compared to the protein alone. The data suggest the possibility that ADP is released in two steps, which would result in bound ADP also being a major intermediate, with bound ADP.P(i) being a very small component. It therefore seems likely that the major transition in structure occurs during the cleavage step, rather than P(i) release. ATP rebinding could then cause reversal of this structural transition. The kinetic mechanism of the PcrA ATPase cycle is very little changed by potential binding to RepD, supporting the idea that RepD increases the processivity of PcrA by increasing affinity to DNA rather than affecting the enzymatic properties per se

Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells.

Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding transcription factors, cell division, and cell proliferation in MCF7 cells, a human breast cancer cell line. Gene transcription was compared between MCF7 cells incubated in (a) glucose/glutamine-free media (control), (b) glucose-containing media to stimulate endogenous lactate production (replicating some of the original Warburg studies), and (c) glucose-containing media supplemented with L-lactate (10 and 20 mM). We found that both endogenous, glucose-derived lactate and exogenous, lactate supplementation significantly affected the transcription of key oncogenes (MYC, RAS, and PI3KCA), transcription factors (HIF1A and E2F1), tumor suppressors (BRCA1, BRCA2) as well as cell cycle and proliferation genes involved in breast cancer (AKT1, ATM, CCND1, CDK4, CDKN1A, CDK2B) (0.001 < p < 0.05 for all genes). Our findings support the hypothesis that lactate acts as an oncometabolite in MCF7 cells. Further research is necessary on other cell lines and biopsy cultures to show generality of the findings and reveal the mechanisms by which dysregulated lactate metabolism could act as an oncometabolite in carcinogenesis

Contact cleaning of polymer film solar reflectors

This paper describes the accelerated ageing of polymer film reflecting surfaces under the conditions to be found during contact cleaning of Concentrating Solar Power (CSP) collectors in the presence of dust and sand particles. In these situations, contact cleaning using brushes and water is required to clean the reflecting surfaces. Whilst suitable for glass reflectors, this paper discusses the effects of existing cleaning processes on the optical and visual properties of polymer film surfaces, and then describes the development of a more benign but effective contact cleaning process for cleaning polymer reflectors. The effects of a range of cleaning brushes are discussed, with and without the presence of water, in the presence of sand and dust particles from selected representative locations. Reflectance measurements and visual inspection shows that a soft cleaning brush with a small amount of water can clean polymer film reflecting surfaces without inflicting surface damage or reducing specular reflectance

Graphene edge structures: Folding, scrolling, tubing, rippling and twisting

Conventional three-dimensional crystal lattices are terminated by surfaces, which can demonstrate complex rebonding and rehybridisation, localised strain and dislocation formation. Two dimensional crystal lattices, of which graphene is the archetype, are terminated by lines. The additional available dimension at such interfaces opens up a range of new topological interface possibilities. We show that graphene sheet edges can adopt a range of topological distortions depending on their nature. Rehybridisation, local bond reordering, chemical functionalisation with bulky, charged, or multi-functional groups can lead to edge buckling to relieve strain, folding, rolling and even tube formation. We discuss the topological possibilities at a 2D graphene edge, and under what circumstances we expect different edge topologies to occur. Density functional calculations are used to explore in more depth different graphene edge types.Comment: Additional figure in published versio

Remittances and banking sector breadth and depth : evidence from Mexico

Despite the rising volume of remittances flowing to developing countries, their impact on banking sector breadth and depth in recipient countries has been largely unexplored. The authors examine this topic using municipio-level data on the fraction of households that receive remittances and on measures of banking breadth and depth for Mexico. They find that remittances are strongly associated with greater banking breadth and depth, increasing the number of branches and accounts per capita and the ratio of deposits to gross domestic product. These effects are significant both statistically and economically, even after conducting robustness tests and addressing the potential endogeneity of remittances.Access to Finance,Banks&Banking Reform,Population Policies,Debt Markets,