Sexual Functioning of Gynecological Cancer Patients: A Literature Review

Background: According to the World Health Organization, cervical, uterine and ovarian cancers were the third, sixth and eighth most common cancers in women worldwide. Unlike other physiological side effects of cancer treatment, sexual problems in gynecological cancer survivors do not tend to resolve after first few years of cancer treatment. However, women who experience sexual dysfunction do not discuss the problem openly with their healthcare professionals.Objective: The objectives of this literature review are to identify, summarize and critically appraise current literatures investigating the sexual functioning and sexual health needs of gynecological cancer patients, as well as to identify the communication between gynecological cancer patients and healthcare professionals.Design: A thorough analysis of the literatures on the topic of sexual functioning of gynecological cancer patients.Data sources: EBSCO host (Medline, CINAL Plus and Academic Search Alumni Edition) and Ovid Technology (British Nursing Index).Review methods: A comprehensive search was conducted in the named data sources from 2003 to 2014 to identify English articles with the keywords “ovarian cancerâ€, “uterine cancerâ€, “cervical cancerâ€, “gynecological cancerâ€, “sexual functioningâ€, “sexuality†and “sexual health needsâ€. Two authors assessed all identified articles independently for inclusion in the review.Results: A total of eight studies were included in the review. All studies focused on the sexual functioning of gynecological cancer patients. Four of them assessed their sexual health needs and one evaluated the communication between the patients and healthcare professionals. The findings indicated that gynecological cancer patients experienced sexual dysfunction after the diagnosis and treatment of the disease. Uncertainty of the side-effects of cancer treatment on bodily functions led to misunderstanding and misconceptions on sexual functioning. Communication, in general, was found to be insufficient between gynecological cancer patients and healthcare professionals.Conclusion: Sexual functioning after the diagnosis and treatment of gynecological cancer requires special attention and care. Appropriate interventions should be developed to meet the patients’ needs. As most of the studies investigating the sexual functioning of gynecological cancer patients were carried out in Western countries, implications for research on this issue in different cultural background is suggested

Existence of Ricci flows of incomplete surfaces

We prove a general existence result for instantaneously complete Ricci flows starting at an arbitrary Riemannian surface which may be incomplete and may have unbounded curvature. We give an explicit formula for the maximal existence time, and describe the asymptotic behaviour in most cases.Comment: 20 pages; updated to reflect galley proof correction

Scaling-violation phenomena and fractality in the human posture control systems

By analyzing the movements of quiet standing persons by means of wavelet statistics, we observe multiple scaling regions in the underlying body dynamics. The use of the wavelet-variance function opens the possibility to relate scaling violations to different modes of posture control. We show that scaling behavior becomes close to perfect, when correctional movements are dominated by the vestibular system.Comment: 12 pages, 4 figures, to appear in Phys. Rev.

Coupled resonator vertical cavity laser diodes

For many applications, the device performance of edge emitting semiconductor lasers can be significantly improved through the use of multiple section devices. For example, cleaved coupled cavity (C3) lasers have been shown to provide single mode operation, wavelength tuning, high speed switching, as well as the generation of short pulses via mode-locking and Q-switching [1]. Using composite resonators within a vertical cavity laser opens up new possibilities due to the unique ability to tailor the coupling between the monolithic cavities, incorporate passive or active resonators which are spectrally degenerate or detuned, and to fabricate these devices in 2-dimensional arrays. Composite resonator vertical cavity lasers (CRVCL) have been examined using optical pumping and electrical injection [2-5]. We report on CRVCL diodes and show that efficient modulation of the laser emission can be achieved by either forward or reverse biasing the passive cavity within a CRVCL

Experimental demonstration of intermodal dispersion in a two-core optical fiber

The recent prediction that intermodal dispersion can play a significant role in pulse evolution in a two-core optical fiber was confirmed experimentally. A picosecond pulse at 1.548µm launched into one core of a meters-long two-core fiber was found to come out of either core of the fiber as two temporally separate pulses. By measuring the time delay between these two pulses, the intermodal dispersion in the fiber was estimated to be 1.13ps/m, in good agreement with theory

Impaired vision in children prenatally exposed to methadone: an observational cohort study

Background/objectives: To examine prevalence of failed visual assessment at 8–10 years in children born to methadone-maintained opioid dependent (MMOD) mothers and relate this to known in utero substance exposure. Subjects/methods: Follow up of observational cohort study of methadone-exposed and comparison children matched for birthweight, gestation and postcode of residence at birth. Participants were 144 children (98 exposed, 46 comparison). Prenatal drug exposure was previously established via comprehensive maternal and neonatal toxicology. Children were invited to attend for visual assessment and casenotes were reviewed. Presence of acuity poorer than 0.2 logMAR, strabismus, nystagmus and/or impaired stereovision constituted a ‘fail’. Fail rates were compared between methadone-exposed and comparison children after adjusting for known confounding variables. Results: 33 children attended in person: data were also derived from casenote review for all children. After controlling for maternal reported tobacco use, methadone-exposed children were more likely to have a visual ‘fail’ outcome, adjusted odds ratio 2.6, 95% CI 1.1–6.2; adjusted relative risk 1.8 (95% CI 1.1–3.4). Visual ‘fail’ outcome rates did not differ between methadone-exposed children who had (n = 47) or had not (n = 51) received pharmacological treatment for neonatal abstinence/opioid withdrawal syndrome (NAS/NOWS); fail rate 62% vs 53% (95% CI of difference—11–27%). Conclusions: Children born to MMOD mothers are almost twice as likely as unexposed peers to have significant visual abnormalities at primary school age. Prenatal methadone exposure should be considered in the differential diagnosis of nystagmus. Findings support visual assessment prior to school entry for children with any history of prenatal opioid exposure. Trial registration: The study was prospectively registered on ClinicalTrials.gov (NCT03603301), https://clinicaltrials.gov/ct2/show/NCT03603301

Throughput analysis in an automated material handling system

Throughput analysis in an automated material handling system, such as an Automated Storage and Retrieval System(AS/RS), may be a complex problem. In the past, several approaches have been used for such an analysis. This paperpresents a combinatorial ap proach to evaluating the throughput performance of a mini-load system, with simulation as the primary method of investigation.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Measurement of the top pair production cross section in 8 TeV proton-proton collisions using kinematic information in the lepton plus jets final state with ATLAS

A measurement is presented of the $t\bar{t}$ inclusive production cross-section in $pp$ collisions at a center-of-mass energy of $\sqrt{s}=8$ TeV using data collected by the ATLAS detector at the CERN Large Hadron Collider. The measurement was performed in the lepton+jets final state using a data set corresponding to an integrated luminosity of 20.3 fb$^{-1}$. The cross-section was obtained using a likelihood discriminant fit and $b$-jet identification was used to improve the signal-to-background ratio. The inclusive $t\bar{t}$ production cross-section was measured to be $260\pm 1{\textrm{(stat.)}} ^{+22}_{-23} {\textrm{(syst.)}}\pm 8{\textrm{(lumi.)}}\pm 4{\mathrm{(beam)}}$ pb assuming a top-quark mass of 172.5 GeV, in good agreement with the theoretical prediction of $253^{+13}_{-15}$ pb. The $t\bar{t}\to (e,\mu)+{\mathrm{jets}}$ production cross-section in the fiducial region determined by the detector acceptance is also reported.Comment: Published version, 19 pages plus author list (35 pages total), 3 figures, 2 tables, all figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/TOPQ-2013-06

Search for a CP-odd Higgs boson decaying to Zh in pp collisions at √s=8TeV with the ATLAS detector

A search for a heavy, CP-odd Higgs boson, A, decaying into a Zboson and a 125GeV Higgs boson, h, with the ATLAS detector at the LHC is presented. The search uses proton–proton collision data at a centre-of-mass energy of 8TeV corresponding to an integrated luminosity of 20.3fb−1. Decays of CP-even hbosons to ττor bbpairs with the Zboson decaying to electron or muon pairs are considered, as well as h →bbdecays with the Zboson decaying to neutrinos. No evidence for the production of an Aboson in these channels is found and the 95% confidence level upper limits derived for σ(gg→A) ×BR(A →Zh) ×BR(h →f¯f)are 0.098–0.013pb for f=τand 0.57–0.014pb for f=bin a range of mA=220–1000GeV. The results are combined and interpreted in the context of two-Higgs-doublet models. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons

Observation of top-quark pair production in association with a photon and measurement of the ttγ production cross section in pp collisions at √s = 7 TeV using the ATLAS detector

A search is performed for top-quark pairs (tt) produced together with a photon (γ) with transverse energy greater than 20 GeV using a sample of tt candidate events in final states with jets, missing transverse momentum, and one isolated electron or muon. The data set used corresponds to an integrated luminosity of 4.59 fb −1 of proton-proton collisions at a center-of-mass energy of 7 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. In total, 140 and 222 ttγ candidate events are observed in the electron and muon channels, to be compared to the expectation of 79 +/- 26 and 120 +/- 39 non-ttγ background events, respectively. The production of ttγ events is observed with a significance of 5.3 standard deviations away from the null hypothesis. The ttγ production cross section times the branching ratio (BR) of the single-lepton decay channel is measured in a fiducial kinematic region within the ATLAS acceptance. The measured value is σ (fid/tty) × BR = 63 +/- 8(stat) (+17/-13)(syst) +/- 1 lumi fb per lepton flavor, in good agreement with the leading-order theoretical calculation normalized to the next-to-leading-order theoretical prediction of 48 +/- 10 fb