PENGARUH LEARNING ORIENTATION TERHADAP INNOVATIVE BEHAVIOR PADA STUDENT UNION DI UNIVERSITAS CIPUTRA

The propose of this research is to find out the effect of individual innovative behavior on individual innovative behavior with work group cohesion as mediating variable in the context of virtual teams. The method that is used in this research is the analysis method in the form of Partial Least Square (PLS) with software SmartPLS. The sample in this research is the Student Union member of 2020/2021 period International Business Management major that is the number of 36 respondents. Data collection technique in this research is to distribute google form questionnaires with likert scale measurement. Based on data analysis, it is concluded that individual learning orientation (X) and individual innovative behavior (Y) are significant

UNIVERSITY GOING IN CONTEXT: A CASE STUDY OF GUSII STUDENTS OF SOUTHWESTERN KENYA

ABSTRACT Dissertation Title: UNIVERSITY GOING IN CONTEXT: A CASE STUDY OF GUSII STUDENTS OF SOUTHWESTERN KENYA Truphena Moraa Choti, Doctor of Philosophy, 2009 Directed By: Prof. Jing Lin, Department of Education Leadership, Higher Education, and International Education University of Maryland, College Park The main objective of this qualitative ethnographic case study is to ascertain the level of awareness and preparedness among high school students in Gusiiland, Southwestern Kenya, for university education opportunities and possibilities. Through an in-depth interviewing process, a purposive sample of twelve students and four focus groups were conducted in four Gusii high schools to capture students' perceptions and conceptions of the university going process. In addition, twelve parents and eight teachers participated in the study. The data were analyzed to identify a set of ideas, issues and themes from all the participants. Also, data from each target student were analyzed as case study, and later a cross-case analysis was undertaken to refine data across participants and schools. Utilizing the theories of social capital, cultural capital and human capital, this study explores the role of the family, school and community in the preparation of students' university going within their socio-cultural environment. Structural inequality in the distribution of educational resources, rigidness of the curriculum and overemphasis on examinations, extreme poverty and local politics emerged as some the barriers to university pathway for Gusii high school students. To overcome these impediments, students adopted unique strategies characterized by strict study schedule, group networks and holiday tuition to gain entry into university. This research contributes original material on the university going process in Kenya and hopes to shed light for future research in this hitherto unexplored academic area. Finding out what students know about higher education including their plans on how to pay for their university costs is worthwhile in helping Kenyan policy makers and scholars in understanding the needs of prospective undergraduate students entering Kenyan universities

Complexidade nos Ambientes Virtuais de Aprendizagem: Utilização dos emoticons nas redes sociais

Atualmente,grande parte da sociedade está conectada por meio de redes sociais. O meio educacional precisa estar alinhado a essas novas formas de conexão para que o processo ensino/aprendizagem e as relações afetivas advindas dessa conexão encontrem eco num pensamento que privilegie um novo paradigma. A pesquisa é um estudo de caso com abordagem quanti-qualitativa.Este artigo tem como objetivo, o estudo da utilização dos emoticons (emojis) nas redes sociais, percebendo desta forma, como o ser humano em sua complexidade por meio das interações sociais permitem que suas emoções se evidenciem com a utilização desses também chamados ideogramas.

The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer

The most devastating aspect of cancer is the emergence of metastases. Thus, identification of potentially metastatic cells among a tumor cell population and the underlying molecular changes that switch cells to a metastatic state are among the most important issues in cancer biology. Here we show that, although normal human colonic epithelial cells lack the glycosphingolipid globotriaosylceramide (Gb3), this molecule is highly expressed in metastatic colon cancer. In addition, a subpopulation of cells that are greatly enriched in Gb3 and have an invasive phenotype was identified in human colon cancer cell lines. In epithelial cells in culture, Gb3 was necessary and sufficient for cell invasiveness. Transfection of Gb3 synthase, resulting in Gb3 expression in noncancerous polarized epithelial cells lacking endogenous Gb3, induced cell invasiveness. Furthermore, Gb3 knockdown by small inhibitory RNA in colon cancer epithelial cells inhibited cell invasiveness. Gb3 is the plasma membrane receptor for Shiga toxin 1. The noncatalytic B subunit of Shiga toxin 1 causes apoptosis of human colon cancer cells expressing Gb3. Injections of the B subunit of Shiga toxin 1 into HT29 human colon cancer cells engrafted into the flanks of nude mice inhibited tumor growth. These data demonstrate the appearance of a subpopulation of Gb3 containing epithelial cells in the metastatic stage of human colon cancer and suggest their possible role in colon cancer invasiveness

Transitoriness in cancer patients: a cross-sectional survey of lung and gastrointestinal cancer patients

Objective: Despite earlier diagnosis and advancements in treatment, cancer remains a leading cause of death in the world (13% of all deaths according to the World Health Organization) among men and women. Cancer accounts for approximately 20% of the deaths in the USA every year. Here, we report the findings from a cross-sectional survey of psychosocial factors in lung and gastrointestinal cancer patients. The aim of the study was to explore the associations among transitoriness, uncertainty, and locus of control (LOC) with quality of life. Transitoriness is defined as a person's confrontation with life's finitude due to a cancer diagnosis. Methods: A total of 126 patients with lung or gastrointestinal cancer completed eight self-reporting questionnaires addressing demographics, spiritual perspective, symptom burden, transitoriness, uncertainty, LOC, and quality of life. Results: Transitoriness, uncertainty, and LOC were significantly associated with one another (r = 0.3267, p = 0.0002/r = 0.1994, p = 0.0252, respectively). LOC/belief in chance has a significant inverse relationship with patients' quality of life (r = −0.2505, p = 0.0047). Transitoriness, uncertainty, and LOC were found to have a significant inverse relationship with patients' quality of life (transitoriness state: r = −0.5363, p = 0.0000/trait: r = −0.4629, p = 0.0000/uncertainty: r = −0.4929, p = 0.0000/internal LOC: r = 0.1759, p = 0.0489/chance LOC: r = −0.2505, p = 0.0047). Conclusion: Transitoriness, uncertainty, and LOC are important concepts as they adversely influence patients' quality of life. Incorporating this finding into the care of cancer patients may provide them with the support they need to cope with treatment and maintenance of a positive quality of lif

A Preliminary Analysis of Combined Liver Resection With New Chemotherapy for Synchronous and Metachronous Colorectal Liver Metastasis

ObjectiveTo compare the survival between patients with synchronous and metachronous colorectal liver metastases after hepatectomy with new generation of perioperative chemotherapy.MethodsFrom October 2002 to January 2008, patients receiving hepatectomy for synchronous or metachronous colorectal liver metastasis were studied retrospectively.ResultsFifty-five patients (synchronous group = 35, metachronous group = 20) underwent hepatectomy for colorectal liver metastases. Besides younger age with male predominance, patients in the synchronous group had more tumour multinodularity and bilobe liver involvement. They had received less hepatic curative hepatectomy (81.1% vs. 100%) with a higher rate of peri-operative chemotherapy (91.4% vs. 50%) and postoperative morbidity (25.7% vs. 0%). However both groups had no statistical significant difference in median overall survival (OS) and disease free survival (DFS). Inferior OS and DFS were observed in the synchronous group for patients who had no peri-operative chemotherapy or those showing poor response to chemotherapy. The most favourable OS is observed in both groups after performing globally curative hepatectomy.ConclusionSynchronous colorectal liver metastasis is not a poor prognostic factor for survival when compared with the metachronous metastasis. Globally curative hepatectomy in combination of new generation of chemotherapy is recommended for the management of resectable colorectal liver metastasis

Lattice Boltzmann Method For Fast Patient-Specific Simulation of Liver Tumor Ablation from CT Images

International audienceRadio-frequency ablation (RFA), the most widely used minimally invasive ablative therapy of liver cancer, is challenged by a lack of patient-specifi c planning. In particular, the presence of blood vessels and time varying thermal di ffusivity makes the prediction of the extent of the ablated tissue diffi cult. This may result in incomplete treatments and increased risk of recurrence. We propose a new model of the physical mechanisms involved in RFA of abdominal tumors based on Lattice Boltzmann Method to predict the extent of ablation given the probe location and the biological parameters. Our method relies on patient images, from which level set representations of liver geometry, tumor shape and vessels are extracted. Then a computational model of heat diff usion, cellular necrosis and blood flow through vessels and liver is solved to estimate the extent of ablated tissue. After quantitative verifi cations against an analytical solution, we apply our framework to 5 patients datasets which include pre- and post-operative CT images, yielding promising correlation between predicted and actual ablation extent (mean point to mesh errors of 8.7 mm). Implemented on graphics processing units, our method may enable RFA planning in clinical settings as it leads to near real-time computation: 1 minute of ablation is simulated in 1.14 minutes,which is almost 60 faster than standard fi nite element method