126 research outputs found

    Real spectra in 1D single-band non-Hermitian Hamiltonians

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    In general, the energy spectrum of a non-Hermitian system turns out to be complex, which is not so satisfactory since the time evolution of eigenstates with complex eigenvalues is either exponentially growing or decaying. Here we provide a sufficient and necessary condition of the real spectrum under open boundary conditions for one-dimensional non-Hermitian tight-binding Hamiltonians. The necessity is directly related to the fact that the generalized Brillouin zone in one dimension is a closed loop with the origin in its interior. For some simple models, we demonstrate the sufficiency by analytically determining when the preimage of the characteristic polynomial contains a loop and showing that this loop is just the generalized Brillouin zone itself. For more complex models, the numerical results are shown. Our results indicate that real spectra are more common than one may have expected in non-Hermitian systems and are helpful for designing non-Hermitian models with real spectra

    Study on the relationship between tsunami waves in dam break state and initial water levels

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    Tsunami wave characteristics are greatly influenced by the initial water level when they attack structures. In this study, experimental and numerical investigations were conducted to investigated the relationship between tsunami wave characteristics and initial water levels. Results showed that, the wave height, wave velocity, and Froude number increase with the increase of tsunami wave intensity; the time history of water levels were influenced by the different initial water level conditions; the analytical solution proposed by Chanson (2005) may be extended to wet-bed conditions (for initial water level < 0.36 tsunami bore height in our experimental set-up). Due to the limitations of experimental ranges in the laboratory, the validated numerical model can provide more results for wider experimental ranges for tsunami bore investigations. It was observed from numerical results that, tsunami bore height increases with the increase of reservoir water level; tsunami bore velocity decreases with the increased initial water level on the bed; as the initial water level on the bed gradually increases, the mean tsunami bore Froude number shows a downward trend

    Does the nudge effect persist? Evidence from a fi eld experiment using social comparison message in China

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    We designed and carried out a field experiment in which we imposed social comparison incentives and technical recommendations on student dormitories through electricity consumption reports and energy-saving suggestions materials, respectively. Our findings are as follows: 1) Regression results on all users show that the effect of social norms is not statistically significant. 2) A social comparison message has a heterogeneous effect on consumers' energy use. Low and high energy users reduced their electricity consumption by 26% and 14%, respectively, in the first week after the treatment. 3) The effect of social norms is time sensitive

    Microbiome and Cancer Immunotherapies

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    Here, we present 3 different perspectives on how the microbiome has impacted cancer patients, treatment, and clinical studies. We hear about the challenges of implementing microbiome analyses into the clinics, the impact these analyses might have on patients\u27 care, and treatment in the future, specifically for gastric cancer treatment. These are a few of the many voices that are highlighting the role of the microbiome in cancer development, treatment, and clinical outcomes

    The role of 39 psoriasis risk variants on age of psoriasis onset.

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    Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored. The goal of this study was to evaluate known risk alleles of psoriasis for association with age of psoriasis onset in three well-defined case-only cohorts totaling 1,498 psoriasis patients. We selected 39 genetic variants from psoriasis GWAS and tested these variants for association with age of psoriasis onset in a meta-analysis. We found that rs10484554 and rs12191877 near HLA-C and rs17716942 near IFIH1 were associated with age of psoriasis onset with false discovery rate &lt; 0.05. The association between rs17716942 and age of onset was not replicated in a fourth independent cohort of 489 patients (P = 0.94). The imputed HLA-C∗06:02 allele demonstrated a much stronger association with age of psoriasis onset than rs10484554 and rs12191877. We conclude that despite the discovery of numerous psoriasis risk alleles, HLA-C∗06:02 still plays the most important role in determining the age of onset of psoriasis. Larger studies are needed to evaluate the contribution of other risk alleles, including IFIH1, to age of psoriasis onset
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