836 research outputs found
Could Alfa fibers substitute glass fibers in composite materials?
In the present work polyester resin composites with Alfa fibers in the form of pulp were prepared and their properties were compared with those of polyester resin reinforced with glass fibers, the latter composites being widely used for structural applications. The composites were prepared using two manufacturing processes, namely hand lay-up and vacuum molding, to assess the influence of the process on the composites properties. Firstly, the tensile properties for the two composites were evaluated. The composites thermal properties were
studied by differential scanning calorimetry and thermogravimetric analysis. Finally, the morphology of a glass fiber composite (GFC) and Alfa pulp composite (APC) was analyzed by scanning electron microscopy, to characterize the composites surface and cross-sections.The authors would like to thank CTC (Centre technique de la
Chimie) for their valuable help during mechanical testing.
The company Solutions Composites, especially Mr.Adel Hammami is gratefully acknowledged for financial and material
support. The authors also wish to thank the members of the Department of Polymer Engineering University of Minho, GuimarĂŁes, Portugal for their valuable cooperation. This research
work is carried out as part of a mobidocPhD, a program financed by the European Union within Pasri Projet. M.C Paiva
acknowledges the Portuguese Foundation for Science and
Technology (FCT) and the European program FEDER/COMPETE for the financial support through project PEst-C/CTM/
LA0025/2013 (LA 25-2015-2017)
Production of cellulose nanofibers from Alfa grass and application as reinforcement for polyvinyl alcohol
The work reported demonstrates an simple method of extracting cellulose nanofibers (CNF)
from cellulose microfibers (CMF) obtained from the plant Stipatenacissima. Here, a method
for the production of CNF from CMF extracted from Alfa grass by exfoliation in polyvinyl
alcohol (PVA) solution, is demonstrated. The CMF were produced in powder form and
exfoliated in PVA aqueous solution to produce composites with 2, 4, 5 and 10 wt-% of CNF.
Scanning Electron Microscopy demonstrated exfoliation of CMF, dispersion of the CNF and
wetting by the polymer. The composites were characterised by thermogravimetry,
differential scanning calorimetry, X-ray diffraction and tensile testing. The addition of CNF to
PVA reduced the crystallinity degree of PVA. The large increase of the Youngâs modulus from
38 to 113% (relative to pure PVA) for composites with 2 to 10 wt-% of CNF incorporation is
consistent with the extensive exfoliation of CMF into CNF and its excellent interface with PVA.The authors acknowledge the Portuguese Foundation for
Science and Technology (FCT) for project PEst-C/CTM/
LA0025/2013 (Strategic Project - LA 25 - 2013â2014).
Salma Ben Cheikh acknowledges the Ministry of Higher
Education and Scientific Research (Tunisia) for a grant to
travel to IPC/i3N in Portugal
Mauritanie
GĂ©ographie La Mauritanie sâĂ©tend sur une superficie 1.030.700 km2. Elle est bordĂ©e Ă lâouest par lâOcĂ©an Atlantique. Ses frontiĂšres nord la mettent en contact avec lâĐ”Ń
-Sahara espagnol et lâAlgĂ©rie. Elle est limitĂ©e Ă lâest par le Mali et au sud par le SĂ©nĂ©gal, dont elle est sĂ©parĂ©e par le fleuve du mĂȘme nom. Notons au passage que ce nom nâest peut-ĂȘtre pas sans rapport, si lâon en croit certains textes portugais, avec la langue et la culture berbĂšres « zĂ©naga », dont il sera question plus lo..
Maures contemporains
Aujourdâhui, dans les rĂ©gions occidentales du Sahara, les Maures se reconnaissent essentiellement Ă lâusage de lâarabe dialectal áž„assÄniyya (ou áž„assÄni) et Ă une culture largement commune dont les traits les plus saillants sont les vĂȘtements (mĂ€lÉáž„fĂ€ « voile » des femmes, áž„awli « turban » et daáčáčÄâa « boubou » des hommes) et le remplacement, dans le systĂšme anthroponymique, de bin et bint par wÉll (transcrit souvent ould) et mÉnt (X wÉll / mÉnt Y... « X fils / fille de Y »). Ils sont approxim..
Influence of integrated services on postpartum family planning use: a cross-sectional survey from urban Senegal
Abstract Background Although the majority of postpartum women indicate a desire to delay a next birth, family planning (FP) methods are often not offered to, or taken up by, women in the first year postpartum. This study uses data from urban Senegal to examine exposure to FP information and services at the time of delivery and at child immunization appointments and to determine if these points of integration are associated with greater use of postpartum FP. Methods A representative, household sample of women, ages 15â49, was surveyed from six cities in Senegal in 2011. This study focuses on women who were within two years postpartum (nâ=â1879). We also include women who were surveyed through exit interviews after a visit to a high volume health facility in the same six cities; clients included were visiting the health facility for delivery, post-abortion care, postnatal care, and child immunization services (nâ=â794). Descriptive analyses are presented to examine exposure to FP services among postpartum women and women visiting the health facility. Logistic regression models are used to estimate the effect of integrated services on postpartum FP use in the household sample of women. Analyses were conducted using Stata version 12. Results Among exit interview clients, knowledge of integrated services is high but only a few reported receiving FP services. A majority of the women who did not receive FP services indicated an interest in receiving such information and services. Among the household sample of women up to two-years postpartum, those who received FP information at the time of delivery are more likely to be using modern FP postpartum than their counterparts who also delivered in a facility but did not receive such information. Exposure to FP services at an immunization visit was not significantly related to postpartum FP use. Another key finding is that women with greater self-efficacy are more likely to use a modern FP method. Conclusion This studyâs findings lend strong support for the need to improve integration of FP services into maternal, newborn, and child health services with the goal of increasing postpartum womenâs use of FP methods in urban Senegal
Impact of annual praziquantel treatment on urogenital schistosomiasis in a seasonal transmission focus in central Senegal
In Sub-Saharan Africa, urogenital schistosomiasis remains a significant public health problem, causing 150.000 deaths/year with approximately 112 million cases diagnosed. The Niakhar district is a disease hotspot in central Senegal where transmission occurs seasonally with high prevalences. The aim of this study was to determine the effect of annual treatment over 3 years on the seasonal transmission dynamics of S. haematobium in 9 villages in the Niakhar district. Adults and children aged between 5 and 60 years were surveyed from 2011 to 2014. Urine samples were collected door-to-door and examined for S. haematobium eggs at baseline in June 2011, and all participants were treated in August 2011 with PZQ (40 mg/kg). After this initial examination, evaluations were conducted at 3 successive time points from September 2011 to March 2014, to measure the efficacy of the annual treatments and the rates of reinfection. Each year, during the transmission period, from July to November-December, malacological surveys were also carried out in the fresh water bodies of each village to evaluate the infestation of the snail intermediate hosts. At baseline, the overall prevalence of S. haematobium infection was 57.7%, and the proportion of heavy infection was 45.3%, but one month after the first treatment high cure rates (92.9%) were obtained. The overall infection prevalence and proportion of heavy infection intensities were drastically reduced to 4.2% and 2.3%, respectively. The level of the first reinfection in February-March 2012 was 9.5%. At follow-up time points, prevalence levels varied slightly between reinfection and treatment from 9.5% in June 2012 to 0.3% in March 2013, 11.2 in June 2013, and 10.1% April 2014. At the end of the study, overall prevalence was significantly reduced from 57.7% to 10.1%. The overall rate of infested Bulinid snails was reduced after repeated treatment from 0.8% in 2012 to 0.5% in 2013. Repeated annual treatments are suggested to have a considerable impact on the transmission dynamics of S. haematobium in Niakhar, due to the nature of the epidemiological system with seasonal transmission. Thus, to maintain this benefit and continue to reduce the morbidity of urogenital schistosomiasis, other approaches should be integrated into the strategy plans of the National program to achieve the goal of urogenital schistosomiasis elimination in seasonal foci in Senegal
Graph-Based Approach for Spatial Heterogeneity Analysis in Tumor Microenvironment
Introduction/ Background
The interaction between tumor and surrounding microenvironment (TME) is recognized as playing
an important role in the progression of the disease. Understanding of the interaction between tumor and
immune system is the focus of several studies dedicated to the improvement of cancer immunotherapy
effectiveness [1]. On the other hand, it has been shown that invasion and metastasis of breast tumors is influenced by collagen organization at the tumor-stromal interface [2]. The characterization of such interactions relies on an efficient spatial distribution quantification of TME. Graph-based analysis tools are the best suitable to answer this question as they have the ability to represent spatial arrangements and neighborhood relationships of different tissue components [3].
Aims
In this work, we propose a novel approach to characterize the spatial relationships between cancer cells and TME components in breast tumors, using graph theory and sparse setsâ mathematical morphology (MM). The tools of morphology on graphs were first used in [4] to study the neighborhood relationships between cells in germinal centers from lymph nodes, then in [5] for semantic spatial configuration modeling in histopathology. In our study, we propose new morphological descriptors characterizing the tumor architecture and the interactions with TME cells.
Methods
Towards a better evaluation and understanding, we use simulated data of different breast tumor types , , where locations of cancer nuclei (CN), fibroblasts (synthesizers of collagen, FN), and lymphocytes (LN) are already known. In order to set neighborhood relationships between different cells, Delaunay graph [3] is first reconstructed on all cells, and alpha-shape filter [5] is applied to circumvent border effects, giving new graph denoted G . The designed features are extracted basically from two different morphological operations. The first operation is composed of successive morphological erosions [4] applied to the subgraph induced by CN (denoted SGC, ), repeated until the subgraph is null. The curve given by the number of CN in terms of erosions provides 3 significant characteristics : I) The origin slope describes the number of CN on the boundary of tumor aggregates (TA) and, thus, the tumor-stromal interface ; II) The area under curve (AUC) reflects the density within TAs, and III) the number of iterations outlines the morphologic radius of the largest TA and, consequently, the geodesic distance of the farthest tumor cell from LN and/or FN. The second morphological operation is composed of successive morphological dilations applied to SGC with non-overlapping control of labeled connected-components . The goal behind this operation is to investigate the TME cells surrounding each TA. The ratio between the number of LN and the number of CN, and the means of the Euclidean and the geodesic distances of LN from CN on the boundary are calculated for each TA .
Results
In this work, we have briefly presented a conceptual framework for analyzing the architecture of breast
tumors and the interactions with the surrounding microenvironment. New graph-based features were
proposed to characterize the spatial distribution of TME components and were tested on simulated data. In our future works, we will include adipose tissue [6], blood vessels and endothelial cells. We will also focus on the anisotropic characterization of collagen, and test the approach on real dataset
International standards for early fetal size and pregnancy dating based on ultrasound measurement of crown-rump length in the first trimester of pregnancy.
OBJECTIVES: There are no international standards for relating fetal crown-rump length (CRL) to gestational age (GA), and most existing charts have considerable methodological limitations. The INTERGROWTH-21(st) Project aimed to produce the first international standards for early fetal size and ultrasound dating of pregnancy based on CRL measurement.
METHODS: Urban areas in eight geographically diverse countries that met strict eligibility criteria were selected for the prospective, population-based recruitment, between 9â+â0 and 13â+â6âweeks' gestation, of healthy well-nourished women with singleton pregnancies at low risk of fetal growth impairment. GA was calculated on the basis of a certain last menstrual period, regular menstrual cycle and lack of hormonal medication or breastfeeding in the preceding 2 months. CRL was measured using strict protocols and quality-control measures. All women were followed up throughout pregnancy until delivery and hospital discharge. Cases of neonatal and fetal death, severe pregnancy complications and congenital abnormalities were excluded from the study.
RESULTS: A total of 4607 women were enrolled in the Fetal Growth Longitudinal Study, one of the three main components of the INTERGROWTH-21(st) Project, of whom 4321 had a live singleton birth in the absence of severe maternal conditions or congenital abnormalities detected by ultrasound or at birth. The CRL was measured in 56 women at <â9â+â0âweeks' gestation; these were excluded, resulting in 4265 women who contributed data to the final analysis. The mean CRL and SD increased with GA almost linearly, and their relationship to GA is given by the following two equations (in which GA is in days and CRL in mm): mean CRLâ=â-50.6562 + (0.815118 Ă GA) + (0.00535302âĂ GA(2) ); and SD of CRLâ=â-2.21626â+â(0.0984894âĂâGA).
GA estimation is carried out according to the two equations: GAâ=â40.9041â+â(3.21585âĂâCRL(0.5) )â+â(0.348956 Ă CRL); and SD of GAâ=â2.39102â+â(0.0193474âĂâCRL).
CONCLUSIONS: We have produced international prescriptive standards for early fetal linear size and ultrasound dating of pregnancy in the first trimester that can be used throughout the world
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