245 research outputs found

    Truffes (Terfas) De Mesrata, En Tripolitaine

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    Le commerce de l’estampe moderne et contemporaine

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    Marie-Cécile Miessner : Nous allons débattre du commerce de l’estampe contemporaine avec deux personnalités éminentes : Mireille Romand, cinquième génération de marchands, présidente de la Chambre syndicale de l’estampe, du dessin et du tableau, directrice la galerie Documents 15 (15 rue de l’Échaudé, Paris Ve) qu’elle a créée en juin 2012 avec Érik Desmazières, Helena Arrellano Mayz et depuis juin 2013 une quatrième associée : Ulrika Peppler Barry. La galerie se spécialise dans l’estampe et ..

    Amphiphilic block copolymers enhance the cellular uptake of DNA molecules through a facilitated plasma membrane transport

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    Amphiphilic block copolymers have been developed recently for their efficient, in vivo transfection activities in various tissues. Surprisingly, we observed that amphiphilic block copolymers such as Lutrol® do not allow the transfection of cultured cells in vitro, suggesting that the cell environment is strongly involved in their mechanism of action. In an in vitro model mimicking the in vivo situation we showed that pre-treatment of cells with Lutrol®, prior to their incubation with DNA molecules in the presence of cationic lipid, resulted in higher levels of reporter gene expression. We also showed that this improvement in transfection efficiency associated with the presence of Lutrol® was observed irrespective of the plasmid promoter. Considering the various steps that could be improved by Lutrol®, we concluded that the nucleic acids molecule internalization step is the most important barrier affected by Lutrol®. Microscopic examination of transfected cells pre-treated with Lutrol® confirmed that more plasmid DNA copies were internalized. Absence of cationic lipid did not impair Lutrol®-mediated DNA internalization, but critically impaired endosomal escape. Our results strongly suggest that in vivo, Lutrol® improves transfection by a physicochemical mechanism, leading to cellular uptake enhancement through a direct delivery into the cytoplasm, and not via endosomal pathways

    Lula’s Brazil in Africa: cultural diplomacy as an instrument of soft power

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    During the Lula government, cultural  diplomacy was used as an important instrument to exercise soft power and to carve out a leading role for Brazil ininternational politics. The range of Brazil's partners in the domain of cultural diplomacy widened as Brazil's relations with the global South and the African continent expanded, as part of a broaderstrategy to obtain a more prominent role in global affairs. This paper investigates this movement of greater Brazilian activism in the area of cultural diplomacy on the African continent as an illustration of the political significance of South-South relations and of Brazil's attempt to achieve its goal to be a global player through soft power.Durante o Governo Lula, a diplomacia cultural foi utilizada como importante instrumento para que o Brasil exercesse poder brando ("soft power") e assumisse um papel de liderança na política internacional. O número de parceiros doBrasil no campo da diplomacia cultural oi ampliado, enquanto suas relações com o Sul global e o continente africanose expandiram, como parte de uma estratégia mais abrangente em assuntos globais. O presente artigo investiga essemovimento de maior ativismo na área da diplomacia cultural no continente africano como ilustração da importânciadas relações Sul-Sul e da tentativa do Brasil de atingir seu objetivo de tornar-se um ator global através do poder brando

    On the Structure of the Cyst Wall of Heterodera schachtii

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    Les conflits relatifs à la garde des enfants et au droit de visite en droit international privé

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    Chatin Louis. Les conflits relatifs à la garde des enfants et au droit de visite en droit international privé. In: Droit international privé : travaux du Comité français de droit international privé, 4e année, 1981-1982. 1985. pp. 107-138

    Discours de M. Chatin.

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    La trichine et la trichinose

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    L’histologie zoologique

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    Chatin Joannes. L’histologie zoologique. In: Revue internationale de l'enseignement, tome 22, Juillet-Décembre 1891. pp. 25-38

    Brazil:analysis of a rising soft power

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