98 research outputs found

    Viewing novels, reading films: Stanley Kubrick and the art of adaptation as interpretation

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    Greg Jenkins has observed that adaptation is a presence that is woven into the very fabric of film culture. Although this statement is true, no definitive theory of adaptation exists. Critics and scholars ponder adaptation, yet cannot seem to agree on what makes an adaptation a success or a failure. The problem of adaptation stems from many sources. What, if anything, does a film owe the novel on which it is based? How, if possible, does a film remain faithful to its source? Is a film a version of a story or its own autonomous work of art? Who is the author of this work? What is an Author? Which text is given primacy: the novel or the film? What is a Text? These questions, and many others, are at the heart of adaptation studies. This project does not pretend to address them all, nor does it claim to be the final answer to the question of adaptation. It does, however, provide a possible solution that is both theoretical and practical. It is theoretical in that it asks viewers to consider what a particular adaptation is doing with a film; practical in that it attempts to bring method to the madness by applying the theory to a sample case study: Stanley Kubrick. Kubrick is not an arbitrary choice as he encompasses the major questions of adaptation. Although all of Kubrick\u27s major films were based on works of fiction, he fits into that highest echelon of filmmakers, the auteur. He is the unquestioned author of his canon. The range of Kubrick\u27s films also proves useful for this study: most of Kubrick\u27s adaptations are successful, a few are not; many of his films have surpassed their literary ancestors, others have elevated them to new heights; some stay rather faithful to the source text, others deviate greatly. This discussion will consider the films of Kubrick\u27s canon that center on two of his recurring themes, love and war, by considering each novel\u27s thematic appeal for Kubrick followed by an analysis of the film in terms of what it is doing with the text

    The Role of Factor XI During Murine Polymicrobial Sepsis

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    Qualitative evaluation of paediatric burn injury in Malawi: assessing opportunities for injury prevention

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    Introduction: The burden of burn injury in sub-Saharan Africa is high and children bare a disproportional share of the injury burden. Methods: This is a prospective qualitative study of paediatric burn survivors (age, ≤8 years) admitted to Kamuzu Central Hospital (KCH) in Lilongwe, Malawi. Results: There were a total of 72 guardians interviewed for the purpose of the study. The most frequent mechanisms of burn injury were flames and scalds in 44.4% and 38.9%, respectively. Mothers were present at the time of the burn injury in only 23.6% of cases, while 22.2% of children were unmonitored at the time of injury. A total of 55.6% of burn injuries was cooking-related. Conclusion: Burn prevention strategies are necessary for addressing the high rates of burns for children in sub-Saharan Africa. The must be focused on mothers and caregivers burn education in the home, particularly as it relates to cooking and parental oversight

    Coastal Ocean Processes : a science prospectus

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    CoOP (Coastal Ocean Processes) is an organization meant to study major interdisciplinary scientific problems in the coastal ocean. Its goal is "to obtain a new level of quantitative understanding of the processes that dominate the transformations, transport and fates of biologically, chemically and geologically important matter on the continental margin". Central to obtaining this understanding will be advances in observing and modeling the cross-shelf component of transport. More specific objectives are to understand 1) cross-margin exchanges, 2) air sea exchanges, 3) benthic-pelagic exchanges, 4) terrestrial inputs and 5) biological and chemical transformations within the water column. CoOP research will be carried out primarly through a series of process-oriented field studies, each involving about two years of measurements. Each of these field studies is to be initiated and defined through a community workshop. In addition to the process studies, CoOP will also involve modeling, long time series, exploratory studies, remote sensing, technological innovation, data archiving and communications. A CoOP pilot study has been approved for funding by the National Science Foundation, and funding will begin in 1992. The CoOP science effort is thus already underway.Funding was provided by the National Science Foundation under Grant No. OCE-9108993

    The Effect of the Earned Income Tax Credit in the District of Columbia on Poverty and Income Dynamics

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    Using unique longitudinal administrative tax panel data for the District of Columbia (DC), we assess the combined effect of the DC supplemental earned income tax credit (EITC) and the federal EITC on poverty and income dynamics within Washington, DC, from 2001 to 2011. The EITC in DC merits investigation, as the DC supplement to the federal credit is the largest in the nation. The supplemental DC EITC was enacted in 2000, and has been expanded from 10 percent of the federal credit in 2001 to 40 percent as of 2009. To implement the study, we estimate least squares models with 0/1 dependent variables to estimate the likelihood of net-EITC income above poverty and near-poverty thresholds. We also estimate the likelihood of earnings growth and income stabilization from the EITC. To identify the effect of the EITC, we exploit variation in the EITC subsidy rate from 2008 to 2009, when an additional EITC bracket of 45 percent was added for workers with three or more dependent children, up from 40 percent in the previous year for workers with two or more children. We also estimate a model examining the impact of city-level changes to the EITC. The structure and richness of our data enable us to control for tax filer fixed effects, an important innovation from many previous EITC studies. Overall, we find that the combined EITC raises the likelihood of net-EITC income above poverty and near poverty by as much as 9 percent, with the largest consistent effects accruing to single-parent families

    The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

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    INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

    Irish Rose

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