52 research outputs found

    Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo

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    This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from the CAS-Novonordisk Foundation all to JRS. We are grateful to all the members of Molecular Energetics Group for their support and discussion of the results. We would like to thank the Center for Biological Imaging from Institute of Biophysics Chinese Academy of Sciences and Professor Zhaohui Wang's Lab from Institute of Genetics and Developmental Biology Chinese Academy of Sciences for confocal microscopy and the Center for Developmental Biology from Institute of Genetics and Developmental Biology Chinese Academy of Sciences and Dr. Jai from Core Facility for Protein Research from Institute of Biophysics Chinese Academy of Sciences for flow cytometry. We are grateful to Dr. Kuang from Purdue University and Dr. Zhu from Chinese Academy of Medical Sciences Peking Union Medical College for the kind donation of Myf5-Cre mice and Dr. Wolfrum from the Institute of Food Nutrition and Health at the ETH Zurich for the kind donation of the Ucp1-DTR mice. Xun Huang provided valuable comments on previous versions of the manuscript.Peer reviewedPublisher PD

    No seasonal variation in physical activity of Han Chinese living in Beijing

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    Acknowledgements We are also grateful for the support of all the volunteers who participated in our study. We are grateful to Beijing Urban Ecosystem Research Station provided the hourly temperature and PM 2.5 data. We are grateful to the USA CDC for the loan of some of the GT3X accelerometers used in this study. Funding This study was funded by National Natural Science Foundation of China (NSFC 91431102) and International Cooperation Program of Chinese Academy of Sciences (GJHZ1660). John R. Speakman was supported by the 1000 talents program of the Chinese government and a Wolfson merit award from the Royal Society.Peer reviewedPublisher PD

    Impact of dietary sucrose on adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion : liquid or solid

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    The study was funded by the Chinese Academy of Sciences Strategic Program (XDB13030100), the 1000 Talents program, and the National Natural Science Foundation of China (91649108) and a Wolfson merit award from the Royal Society all to J.R.S.; J.T was supported by the CAS-TWAS president's fellowship.Peer reviewedPublisher PD

    Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice

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    Acknowledgements This work was supported by the National Natural Science Foundation of China (92057206), the KC Wong Education Foundation, as well as grants from the ‘1000 talents’ recruitment program, a PIFI professorial fellowship from CAS and a Wolfson merit professorship from the UK Royal Society, all to J.R.S. We are grateful to all the members of the Molecular Energetics Group for their support and discussion of the results. We would like to thank Peter Thomson and Marina Stamatiou for technical assistance with the DLW measurements.Peer reviewedPublisher PD

    Different impacts of resources on opposite sex ratings of physical attractiveness by males and females

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    This work was supported by National Natural Science Foundation of China (NSFC grant 91431102) and International Cooperation Program of Chinese Academy of Sciences (GJHZ1660). John R. Speakman was supported by the 1000 talents program of the Chinese government and a Wolfson merit award from the Royal Society. Guanlin Wang was awarded by the UCAS-UoA dual degree PhD training Program.Peer reviewedPostprin

    Increased Variation in Body Weight and Food Intake Is Related to Increased Dietary Fat but Not Increased Carbohydrate or Protein in Mice

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    Funding This study was funded by the National Key R&D Program of China (2019YFA0801900) to JS and the Postdoctoral Innovation Fund (2021) to YW. The original diet exposure experiment was funded by the Chinese Academy of Sciences Strategic Program (XDB13030100). JS was also supported during this work by a PIFI professorial fellowship from CAS and a Wolfson merit award from the UK Royal Society. CORRECTION article Front. Nutr., 21 October 2022 Sec. Nutrition and Metabolism https://doi.org/10.3389/fnut.2022.1049766 Corrigendum: Increased variation in body weight and food intake is related to increased dietary fat but not increased carbohydrate or protein in micePeer reviewedPublisher PD

    A single nucleotide mutation in the dual-oxidase 2 (DUOX2) gene causes some of the panda's unique metabolic phenotypes

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    This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030100 and XDB29020000), the Creative Research Group Project of National Natural Science Foundation of China (31821001), the Key Project of the Chinese Academy of Sciences (QYZDB-SSW-SMC047), the National Key Research and Development Program of China (2018YFC2000500), the Chinese Academy of Sciences President's International Fellowship Initiative Postdoctoral Fellowship (to A.M.R.) and the President's International Fellowship Initiative Professorial and Wolfson Merit Award (to J.R.S.).Peer reviewedPublisher PD

    Maternal High Fat Diet in Lactation Impacts Hypothalamic Neurogenesis and Neurotrophic Development, Leading to Later Life Susceptibility to Obesity in Male but Not Female Mice

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    Research Funding National Key Research and Development Program of China. Grant Number: 2018YFA0801000 National Natural Science Foundation of China. Grant Number: 92057206 A Wolfson merit professorship from UK Royal Society Postdoctoral Research Foundation of China. Grant Numbers: 2013M540157, 2014T70135 The KC Wong Education Foundation Grants from the "1000 talents" recruitment program A PIFI professional fellowship from CASPeer reviewedPublisher PD

    Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

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    This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and Natural Science Foundation of China (NSFC; 91649108), the Chinese Academy of Sciences-Novo Nordisk Foundation, as well as grants from the Chinese Academy of Sciences “1000 Talents” recruitment program and a “Great-Wall Professorship” from the Chinese Academy of Sciences-Novo Nordisk Foundation. J.R.S. was also supported by a Wolfson merit professorship from The UK Royal Society. We are grateful to all of the members of the Molecular Energetics Group for their support and discussion of the results. We would like to thank Dr. Jia and Dr. Sun from the Core Facility for Protein Research from the Institute of Biophysics, Chinese Academy of Sciences for flow cytometry, and Peter Thomson and Marina Samatiou for technical assistance with the DLW measurements.Peer reviewedPublisher PD

    Effects of dietary macronutrients and body composition on glucose homeostasis in mice

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    Funding This work was supported by the Chinese Academy of Sciences Strategic Programs (XDA12030209 and XDB13030100), the 1000 Talents Program and a Wolfson Merit Award to J.R.SPeer reviewedPublisher PD
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