Labour Migration and Time Use Patterns of the Left-Behind Children and Elderly in Rural China

Rural-urban migration has become a major feature of the Chinese economy since the mid-1990s. Due to institutional arrangements and economic and cultural factors, massive labor migration has resulted in a large left-behind population consisting of children, non-elderly married women, and the elderly. This paper examines the impacts of labor migration on time use patterns of the left-behind elderly people and children in rural China, using data derived from the China’s health and Nutrition Health Survey (CHNS) for the period between 1997 and 2006. The results show that the migration of household members increases the time spent on farm work and domestic work for the left-behind elderly, and the migration of parents increases the time spent on farm work and domestic work for the left-behind children. Importantly, migration has striking gender differentiated impacts with the increase in work time being greater for elderly women and girls than elderly men and boys. These results have important policy implications.

Managing Liberalization and Globalization in Rural China: Trends in Rural Labour Allocation, Income and Inequality

China’s integration into the global economy, while rapid, has been managed as part of a wider liberalization process. The structural changes in the rural economy arising from these twin processes have led to widening intra-rural inequalities. To address these, the central leadership has, in Polanyian manner, moved to counter some of the adverse effects of liberalization and globalization. We discuss this dynamic as it has affected rural China. We analyze results from a national data set covering the period 1991-2006 to assess the extent to which the state has been successful in protecting society from the advance of market forces. We find positive outcomes in terms of real earnings growth and poverty reduction but negative outcomes in terms of the rise in open unemployment and in terms of increasing intra-rural income inequality, although this was noticeably more pronounced in the 1991-2000 period than in the 2000-2006 period when more active government redistributive mechanisms were in place

Land tenure policy and off-farm employment in rural China

Abstract Using the data from the three waves (1995, 2002, and 2008) of the Chinese Household Income Project (CHIP), this paper investigates the impact of land tenure security on farmers’ labor market outcomes in rural China. To identify the effect of land tenure security, this paper used difference-in-differences strategy to control for time invariant heterogeneity and a number of observed time-varying economic characteristics for its validity. The paper finds that in response to more security land rights, both women and men increase their probability of wage employment participation. JEL Classification: O15, J61, Q15, R2

ADT-OH exhibits anti-metastatic activity on triple-negative breast cancer by combinatorial targeting of autophagy and mitochondrial fission

Abstract High basal autophagy and enhanced mitochondrial fission in triple-negative breast cancer (TNBC) cells support cell migration and promote plasticity of cancer cell metabolism. Here, we suggest a novel combination therapy approach for the treatment of TNBC that targets Drp1-mediated mitochondrial fission and autophagy pathways. Hydrogen sulfide (H2S) mediates a myriad of biological processes, including autophagy and mitochondrial function. In this study, we demonstrated that 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT-OH), one of the most widely utilized sustained-release H2S donors, effectively suppresses metastasis of TNBC cells in the absence of proliferation inhibition in vitro and in vivo. ADT-OH treatment ameliorated autophagy flux by suppressing autophagosome formation and induced mitochondrial elongation through decreasing expression of dynamin-related protein 1 (Drp1) and increasing expression of mitochondrial fusion protein (Mfn2). At the same time, ADT-OH downregulated mitophagy flux and inhibited mitochondrial function, eventually leading to the inhibition of migration and invasion in TNBC cells. In vivo, intraperitoneal administration of ADT-OH revealed a potent anti-metastatic activity in three different animal models, the MDA-MB-231 orthotopic xenograft model, the 4T1-Luci orthotopic model and the 4T1-Luci tail vein metastasis model. However, ADT-OH has an extremely low water solubility, which is a significant barrier to its effectiveness. Thus, we demonstrated that the solubility of ADT-OH in water can be improved significantly by absorption with hydroxypropyl-β-cyclodextrin (CD). Remarkably, the obtained CD-ADT-OH demonstrated superior anti-cancer effect to ADT-OH in vivo. Altogether, this study describes a novel regulator of mammalian mitochondrial fission and autophagy, with potential utility as an experimental therapeutic agent for metastatic TNBC

Study on Interaction of Aromatic Substances and Correlation between Electroencephalogram Correlates of Odor Perception in Light Flavor Baijiu

Light-flavor Baijiu (LFB) is widely cherished for its flavor. This study identified the thresholds of 14 aroma compounds in a 52% ethanol-water matrix and conducted a comprehensive analysis of the interactions among key aroma compounds in LFB using the Feller additive model and odor activity values approach. Among them, the interactions of beta-damascenone with ester and alcohol compounds were primarily promotive, while the interaction with acid compounds was predominantly masking. Furthermore, for the first time, the electroencephalogram (EEG) technology was used to characterize the interactions between aroma compounds. The results showed that the brain activity in the alpha frequency band demonstrated heightened olfactory sensitivity. The EEG could not only display the additive effect of odor intensity but also reflect the differences in aroma similarity between different odors. This study demonstrated that the EEG can serve as an effective tool for olfactory assessment

Study on Interaction of Aromatic Substances and Correlation between Electroencephalogram Correlates of Odor Perception in Light Flavor Baijiu

Light-flavor Baijiu (LFB) is widely cherished for its flavor. This study identified the thresholds of 14 aroma compounds in a 52% ethanol-water matrix and conducted a comprehensive analysis of the interactions among key aroma compounds in LFB using the Feller additive model and odor activity values approach. Among them, the interactions of beta-damascenone with ester and alcohol compounds were primarily promotive, while the interaction with acid compounds was predominantly masking. Furthermore, for the first time, the electroencephalogram (EEG) technology was used to characterize the interactions between aroma compounds. The results showed that the brain activity in the alpha frequency band demonstrated heightened olfactory sensitivity. The EEG could not only display the additive effect of odor intensity but also reflect the differences in aroma similarity between different odors. This study demonstrated that the EEG can serve as an effective tool for olfactory assessment