74 research outputs found

    Migration of Virtual Machine to improve the Security of Cloud Computing

    Get PDF
    Cloud services help individuals and organization to use data that are managed by third parties or another person at remote locations. With the increase in the development of cloud computing environment, the security has become the major concern that has been raised more consistently in order to move data and applications to the cloud as individuals do not trust the third party cloud computing providers with their private and most sensitive data and information. This paper presents, the migration of virtual machine to improve the security in cloud computing. Virtual machine (VM) is an emulation of a particular computer system. In cloud computing, virtual machine migration is a useful tool for migrating operating system instances across multiple physical machines. It is used to load balancing, fault management, low-level system maintenance and reduce energy consumption. Virtual machine (VM) migration is a powerful management technique that gives data center operators the ability to adapt the placement of VMs in order to better satisfy performance objectives, improve resource utilization and communication locality, achieve fault tolerance, reduce energy consumption, and facilitate system maintenance activities. In the migration based security approach, proposed the placement of VMs can make enormous difference in terms of security levels. On the bases of survivability analysis of VMs and Discrete Time Markov Chain (DTMC) analysis, we design an algorithm that generates a secure placement arrangement that the guest VMs can moves before succeeds the attack

    A decentralized consensus application using blockchain ecosystem

    Get PDF
    The consensus is a critical operation of any decision-making process. It involves a set of eligible members; whose decision need to be honored by taking their acknowledgment before making any decision. The traditional consensus process follows centralized architecture, the members need to rely on and trust this architecture. The proposed system aims to develop a secure decentralized consensus application in the untrusted environment by making use of blockchain technology along with smart contract and interplanetary file system (IPFS)

    FORMULATION AND EVALUATION OF MOUTH-DISSOLVING FILM OF AN H1 ANTIHISTAMINE DRUG

    Get PDF
    Objective: The objective of present work was to develop a Mouth dissolving film of Levocetirizine dihydrochloride drug by Solvent casting method using different natural polymers. The best polymer was selected on the basis of the release of the drug and disintegration time. Methods: Sodium alginate and Guar gum are used as a natural polymers. Starch is used as a disintegrant. Glycerol is used as a plasticizer. Citric acid is usedas a saliva-stimulating agent. Mannitol is used as a sweetener. Peppermint oil as a flavoring agent. Mouth-dissolving films were prepared by using the solvent casting method. Results: The compatibility study of the drug with different natural polymers was carried out. The IR spectral studies showed no interaction between drug and polymers. Obtained satisfactory results for Preformulation and post-formulation tests. Formulation F6 containing sodium alginate, F9 containing guar gum and F14 containing a combination ratio of (Sodium alginate: guar gum) showed good results throughout the study. The stability studies on the formulations F6, F9 and F14 indicates that there is no significant change in physical appearance, disintegration time and drug content release study. Conclusion: From the results, it was concluded that the Mouth dissolving films of Levocetirizine dihydrochloride containing natural polymer sodium alginate (F6) showed the least disintegration time (14.28 sec), highest dissolution rate (98.24%) than the formulation containing natural polymer guar gum and combination ratio of (Sodium alginate: guar gum)

    Secure Data Control: Privacy and Security based on ABE for Access Control over Cloud

    Get PDF
    In today's world, there is a strong requirement for sharing information over cloud. However, privacy and security remains a setback especially when working with bulk amounts of data in the Cloud. Data is abundantly stored outside the control of the data owner’s machine with lack of his knowledge to the data owner, how the data being used and where the data are being stored. So, there is a necessity for the data owner to have a more control over their data, similar to the level of control they possess when the data are being stored on their own machine. For example, when a data owner shares an important file with his colleague, he cannot trust what his colleague will do with his data. In this paper, we try to address this problem by monitoring and preventing unauthorized operations by the data consumer. We present a solution called Secure-Data, which bundles the data owner’s data and specified policy, based on XACML, in an object called Secure-Data object. Secure-Data enforces the policies set out by the data owner by communicating with the cloud based applications to disable certain operations and/or run a background process for monitoring the data. We define a software based protocol that will enable to secure the data in the cloud and will support the use of the android app for authentication purposes

    Congenital chloride diarrhea: A rare cause of recurrent polyhydramnios

    Get PDF
    Congenital chloride diarrhea (CCD) is a rare, inherited disorder. Our case was a preterm neonate who presented with severe watery diarrhoea since Day 2 of life. There was maternal history of polyhydramnios and dilated bowel loops. The diagnosis of CCD was confirmed by mutation analysis. The infant is 9 months corrected age, on salt and potassium supplementation, with age-appropriate milestones. The diagnosis of CCD must be made early to prevent life-threatening fluid and electrolyte imbalance

    Impact of Capital Budgeting Decision on Profitability of Firm – Selected Listed Automobile Companies in India

    Get PDF
    Purpose: Profitability plays an important function in the business operations and determines the value by which a business is held. The study set to investigate the impact of capital budgeting decisions on profitability of Automobile firms. Capital budgeting particularly addressed five areas of the study that included capital budgeting decisions (acquisition of long-term assets, replacement of long-term assets, investment appraisal techniques, outsourcing expenditure and working capital decisions) had a biggest and significant effect on profitability of the organizations. Β  Methodology: This study basically involved survey of the Automobile Companies listed in NSE in India. Any business that seeks to invest its resources in a project without understanding the risks and returns involved would be held as irresponsible by its owners or shareholders. This study considered 10 companies are taken from Automobile sectors, which is listed in NSE. Correlation and paired T test were used. Β  Findings: This study basically involved survey of the Automobile Companies listed in NSE in India.The findings set up that there was relationship between the independent variables of capital budgeting decisions and profitability. The study was examined the outcome of capital budgeting Impact on profitability of listed firms in India. The independent variables for the study were Capital Budgeting and Profitability. Β  Research implications:Β  it is evident that Maruti and Tata Motors produced positive and statistically significant values for this study (high t-values (12.37 and 11.26), p =0.00) respectively. Eicher Motor resulted a Lowest but insignificant values (t= 2.11, p = 0.07). Β  Originality/Outcome: The study found that positive impact of capital budgeting on profitability of the firms under the study

    Bioactivity of Locally Available Plants on Cotton Whitefly, Bemisia tabaci and the fungus isolated from cotton

    Full text link
    Aqueous, diethyl ether, chloroform, petroleum ether, N-hexane and benzene extracts of locally available plant species were tested for phytochemical and insecticidal bioactivity against cotton whitefly, Bemisia tabaci, under controlled conditions. This study is within bioprospection context, for utilizing local plant species as alternative in sustainable agriculture development. The leaf and stem extract was used. The whole plant extract of T.procumbens followed by N.oleander and V.rosea showed repellent and toxic effect against adult and second nymphal instars. Leaf extract of all three plants showed high inhibition activity against nymphal instars. In case of flower extract less inhibition activity was shown respectively. Fungi which grow on the cotton plant was screened, characterized and checked for antifungal activity against the extracts of the plant material. Phytochemical analysis was also carried out by standard protocols

    INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Screening of potential efficacy of dietary ginger on ethanol induced oxidative stress in rat cardiac tissue: A study on changes in basic metabolic profiles

    Get PDF
    Abstract The present study was premeditated to examine the possible mechanisms where by ginger (Zingiber officinale) could protect cardiac tissue from alcohol toxicity in rats. The carbohydrate metabolic profiles like total carbohydrates, pyruvate, total proteins, free amino acids and lactate levels were measured in heart tissue. The total carbohydrates, pyruvate, and total proteins were significant declined while free amino acids, lactate levels were significant increased in alcohol intoxicated rats. Whereas with ginger (200 mg/kg body weight) treatment shown significant increase in the total carbohydrates, total proteins and pyruvate levels, whereas free amino acids, lactate levels were significant drop in the cardiac tissues. From the present study, we conclude that ginger protects the heart tissue from alcohol toxicity in rats, this may be due to the presence of many bioactive compounds in ginger

    Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton

    Get PDF
    Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector proteins, some of which also play essential roles in ciliogenesis, highlighting the long-standing question of the role of the cilium in PCP. Wdpcp, a PCP effector, was recently shown to regulate both ciliogenesis and collective cell movement, but the underlying mechanism is unknown. Here we show Wdpcp can regulate PCP by direct modulation of the actin cytoskeleton. These studies were made possible by recovery of a Wdpcp mutant mouse model. Wdpcp-deficient mice exhibit phenotypes reminiscent of Bardet-Biedl/Meckel-Gruber ciliopathy syndromes, including cardiac outflow tract and cochlea defects associated with PCP perturbation. We observed Wdpcp is localized to the transition zone, and in Wdpcp-deficient cells, Sept2, Nphp1, and Mks1 were lost from the transition zone, indicating Wdpcp is required for recruitment of proteins essential for ciliogenesis. Wdpcp is also found in the cytoplasm, where it is localized in the actin cytoskeleton and in focal adhesions. Wdpcp interacts with Sept2 and is colocalized with Sept2 in actin filaments, but in Wdpcp-deficient cells, Sept2 was lost from the actin cytoskeleton, suggesting Wdpcp is required for Sept2 recruitment to actin filaments. Significantly, organization of the actin filaments and focal contacts were markedly changed in Wdpcp-deficient cells. This was associated with decreased membrane ruffling, failure to establish cell polarity, and loss of directional cell migration. These results suggest the PCP defects in Wdpcp mutants are not caused by loss of cilia, but by direct disruption of the actin cytoskeleton. Consistent with this, Wdpcp mutant cochlea has normal kinocilia and yet exhibits PCP defects. Together, these findings provide the first evidence, to our knowledge, that a PCP component required for ciliogenesis can directly modulate the actin cytoskeleton to regulate cell polarity and directional cell migration
    • …
    corecore