45,770 research outputs found

    Time delays and energy transport velocities in three dimensional ideal cloaking

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    We obtained the energy transport velocity distribution for a three dimensional ideal cloak explicitly. Near the operation frequency, the energy transport velocity has rather peculiar distribution. The velocity along a line joining the origin of the cloak is a constant, while the velocity approaches zero at the inner boundary of the cloak. A ray pointing right into the origin of the cloak will experience abrupt changes of velocities when it impinges on the inner surface of the cloak. This peculiar distribution causes infinite time delays for the ideal cloak within a geometric optics description.Comment: A scaling factor is added to convert the parameter \tau into the physical tim

    Roles of the Bloom's syndrome helicase in the maintenance of genome stability

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    The RecQ family of DNA helicases is highly conserved in evolution from bacteria to humans. Of the five known human RecQ family members, three (BLM, WRN and RECQ4, which cause Bloom's syndrome, Werner's syndrome and Rothmund-Thomson syndrome respectively) are mutated in distinct clinical disorders associated with cancer predisposition and/or premature aging. BLM forms part of a multienzyme complex including topoisomerase IIIalpha, replication protein A and a newly identified factor called BLAP75. Together, these proteins play a role in the resolution of DNA structures that arise during the process of homologous recombination repair. In the absence of BLM, cells show genomic instability and a high incidence of sister-chromatid exchanges. In addition to a DNA structure-specific helicase activity, BLM also catalyses Holliday-junction branch migration and the annealing of complementary single-stranded DNA molecules

    Piezoelectric copolymer hydrophones for ultrasonic field characterization

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    Hydrophones to be used in the characterization of medical ultrasonic transducers have been fabricated using a new polyvinylidene fluoride/trifluoroethylene (VF2/VF3) copolymer. The copolymer has an advantage over VF2 in that it does not require prestretching before poling. Thin copolymer films can be cast from solution and then poled using the corona discharge method. As there is a need for small‐diameter hydrophones to provide good spatial resolution in measuring highly focused ultrasonic beams, hydrophones with diameter as small as 0.1 mm have been made. Both needle‐type and line hydrophones have been tested and their performance reported. In the case of line hydrophones, the output signal is proportional to the line integral of the acoustic pressure and a computer tomographic technique has been used to reconstruct the beam profiles

    Role of aldehyde chemistry and NO_x concentrations in secondary organic aerosol formation

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    Aldehydes are an important class of products from atmospheric oxidation of hydrocarbons. Isoprene (2-methyl-1,3-butadiene), the most abundantly emitted atmospheric non-methane hydrocarbon, produces a significant amount of secondary organic aerosol (SOA) via methacrolein (a C_4-unsaturated aldehyde) under urban high-NO_x conditions. Previously, we have identified peroxy methacryloyl nitrate (MPAN) as the important intermediate to isoprene and methacrolein SOA in this NO_x regime. Here we show that as a result of this chemistry, NO_2 enhances SOA formation from methacrolein and two other α, β-unsaturated aldehydes, specifically acrolein and crotonaldehyde, a NO_x effect on SOA formation previously unrecognized. Oligoesters of dihydroxycarboxylic acids and hydroxynitrooxycarboxylic acids are observed to increase with increasing NO_2/NO ratio, and previous characterizations are confirmed by both online and offline high-resolution mass spectrometry techniques. Molecular structure also determines the amount of SOA formation, as the SOA mass yields are the highest for aldehydes that are α, β-unsaturated and contain an additional methyl group on the α-carbon. Aerosol formation from 2-methyl-3-buten-2-ol (MBO232) is insignificant, even under high-NO_2 conditions, as PAN (peroxy acyl nitrate, RC(O)OONO_2) formation is structurally unfavorable. At atmospherically relevant NO_2/NO ratios (3–8), the SOA yields from isoprene high-NO_x photooxidation are 3 times greater than previously measured at lower NO_2/NO ratios. At sufficiently high NO_2 concentrations, in systems of α, β-unsaturated aldehydes, SOA formation from subsequent oxidation of products from acyl peroxyl radicals+NO_2 can exceed that from RO_2+HO_2 reactions under the same inorganic seed conditions, making RO_2+NO_2 an important channel for SOA formation

    Fluctuation-enhanced frequency mixing in a nonlinear micromechanical oscillator

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    We study noise-enhanced frequency mixing in an underdamped micromechanical torsional oscillator. The oscillator is electrostatically driven into bistability by a strong, periodic voltage at frequency ωd\omega_d. A second, weak ac voltage is applied at a frequency ω\omega close to ωd\omega_d. Due to nonlinearity in the system, vibrations occur at both ω\omega and 2ωdω2\omega_d-\omega. White noise is injected into the excitation, allowing the system to occasionally overcome the activation barrier and switch between the two states. At the primary drive frequency where the occupations of the two states are approximately equal, we observe noise-induced enhancement of the oscillation amplitudes at both ω\omega and the down-converted frequency 2ωdω2\omega_d-\omega, in agreement with theoretical predictions. Such enhancement occurs as a result of the noise-induced interstate transitions becoming synchronous with the beating between the two driving frequencies.Comment: 4 pages 5 figure

    Phase transition in the Higgs model of scalar dyons

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    In the present paper we investigate the phase transition "Coulomb--confinement" in the Higgs model of abelian scalar dyons -- particles having both, electric ee and magnetic gg, charges. It is shown that by dual symmetry this theory is equivalent to scalar fields with the effective squared electric charge e^{*2}=e^2+g^2. But the Dirac relation distinguishes the electric and magnetic charges of dyons. The following phase transition couplings are obtained in the one--loop approximation: \alpha_{crit}=e^2_{crit}/4\pi\approx 0.19, \tilde\alpha_{crit}=g^2_{crit}/4\pi\approx 1.29 and \alpha^*_{crit}\approx 1.48.Comment: 16 pages, 2 figure

    Long-term outcome in dogs with chronic enteropathies: 203 cases

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