1,851 research outputs found
On the Matrix Equation XA + AX_T = 0, II
The matrix equation was recently introduced by De Ter\\u27an and Dopico to study the dimension of congruence orbits. They reduced the study of this equation to a number of special cases, several of which have not been explicitly solved. In this note we obtain an explicit, closed-form solution in the difficult Type 0-I interaction case
Visual properties of generalized Kloosterman sums
For a positive integer m and a subgroup A of the unit group (Z/mZ)x, the corresponding generalized Kloosterman sum is the function K(a, b, m, A) = ΣuEA e(au+bu-1/m). Unlike classical Kloosterman sums, which are real valued, generalized Kloosterman sums display a surprising array of visual features when their values are plotted in the complex plane. In a variety of instances, we identify the precise number-theoretic conditions that give rise to particular phenomena
BRIC by BRIC : Governance and Energy Security in Developing Countries
Security of energy supply is a top priority of policymakers around the globe,
especially in countries of the economically emerging world. This paper's aim is to investigate the link between the mode of governance in four developing countries and the way policies to secure energy supply are established. The paper looks at the four "BRIC" countries, Brazil, Russia, India, and China. These countries are experiencing rapid economic growth and poverty alleviation but differ in their modes of governance. The four BRIC countries provide a window into the particular relationship between governance and energy security policy in developing countries. From a theoretical stance, a public choice model is applied to energy policies to develop hypotheses relating the similarities and differences of incentive schemes between democratic and authoritarian governments to predict policy outcomes. We hypothesize that authoritarian regimes seek control and the capability to reward and repress social groups by providing public goods, such as energy supply. In the first empirical step, the current energy economic performance is examined by focussing on domestically available resources, de-concentration and decentralization of the supply side and energy development indices. Doing so, the paper modifies the Kaya Identity to figure out the drivers of energy demand. Furthermore, the paper introduces some metrics such as the Herfindahl-Hirschman-Index (HHI) to measure degrees of concentration and centralization and radar-charts to illustrate the metrics graphically. According to our calculation, Russia's electricity generation park is geographically most centralized. China and Russia have the largest plants by mean output and show the lowest degree of concentration. Referring to indicators, ranging from electricity distribution losses, access to electricity, to the consumption to production ratio, and others, the research finds China to have the most secure energy supply among the BRIC countries, while India performs poorly. Energy policies to foster supply security are compared in the paper's second empirical part. It includes systematic in-depth analyses of the government-driven utilization of National Oil Companies (NOCs) and the construction processes of hydroelectric dams. China seems to be able to exclude social, political and environmental costs, prioritizing economic growth over other objectives. This allows Chinese power plants to be built in a faster and in a cheaper way. Finally, evidence is provided that authoritarian systems tend to utilize NOCs for their political purpose. The paper concludes that there is a significant relation between the mode of governance and the way energy supply is secured. As the rest of the developing world industrializes, investigating the BRIC countries now, during their period of transition, provides clues into how other developing countries might respond to the challenges of securing the supply of energy
Genome-wide mapping of the RNA targets of the Pseudomonas aeruginosa riboregulatory protein RsmN
Pseudomonads typically carry multiple non-identical alleles of the post-transcriptional regulator rsmA. In P. aeruginosa, RsmN is notable in that its structural rearrangement confers distinct and overlapping functions with RsmA. However, little is known about the specificities of RsmN for its target RNAs and overall impact on the biology of this pathogen. We purified and mapped 503 transcripts directly bound by RsmN in P. aeruginosa. About 200 of the mRNAs identified encode proteins of demonstrated function including some determining acute and chronic virulence traits. For example, RsmN reduces biofilm development both directly and indirectly via multiple pathways, involving control of Pel exopolysaccharide biosynthesis and c-di-GMP levels. The RsmN targets identified are also shared with RsmA, although deletion of rsmN generally results in less pronounced phenotypes than those observed for ΔrsmA or ΔrsmArsmNind mutants, probably as a consequence of different binding affinities. Targets newly identified for the Rsm system include the small non-coding RNA CrcZ involved in carbon catabolite repression, for which differential binding of RsmN and RsmA to specific CrcZ regions is demonstrated. The results presented here provide new insights into the intricacy of riboregulatory networks involving multiple but distinct RsmA homologues
The Market for Walnuts in Germany and the United States
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of Cologne University of Applied Sciences and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores walnuts export opportunities to the German and US markets
Young Adults View Smartphone Tracking Technologies for COVID-19 as Acceptable:The Case of Taiwan
Taiwan has been successful in controlling the spread of SARS-CoV-2 during the COVID-19 pandemic; however, without a vaccine the threat of a second outbreak remains. Young adults who show few to no symptoms when infected have been identified in many countries as driving the virus' spread through unidentifiable community transmission. Mobile tracking technologies register nearby contacts of a user and notifies them if one later tests positive to the virus, potentially solving this issue; however, the effectiveness of these technologies depends on their acceptance by the public. The current study assessed attitudes towards three tracking technologies (telecommunication network tracking, a government app, and Apple and Google's Bluetooth exposure notification system) among four samples of young Taiwanese adults (aged 25 years or younger). Using Bayesian methods, we find high acceptance for all three tracking technologies (>75%), with acceptance for each technology surpassing 90% if additional privacy measures were included. We consider the policy implications of these results for Taiwan and similar cultures
Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule
In Pseudomonas aeruginosa, quorum sensing (QS) regulates the production of secondary metabolites, many of which are antimicrobials that impact on polymicrobial community composition. Consequently, quenching QS modulates the environmental impact of P. aeruginosa. To identify bacteria capable of inactivating the QS signal molecule 2-heptyl-3- hydroxy-4(1H)-quinolone (PQS), a minimal medium containing PQS as the sole carbon source was used to enrich a Malaysian rainforest soil sample. This yielded an Achromobacter xylosoxidans strain (Q19) that inactivated PQS, yielding a new fluorescent compound (I-PQS) confirmed as PQS-derived using deuterated PQS. The I-PQS structure was elucidated using mass spectrometry and nuclear magnetic resonance spectroscopy as 2-heptyl-2-hydroxy-1,2-dihydroquinoline- 3,4-dione (HHQD). Achromobacter xylosoxidans Q19 oxidized PQS congeners with alkyl chains ranging from C1 to C5 and also N-methyl PQS, yielding the corresponding 2-hydroxy-1,2-dihydroquinoline-3,4- diones, but was unable to inactivate thePQSprecursor HHQ. This indicates that the hydroxyl group at position 3 in PQS is essential and that A. xylosoxidans inactivates PQS via a pathway involving the incorporation of oxygen at C2 of the heterocyclic ring. The conversion of PQS to HHQD also occurred on incubation with 12/17 A. xylosoxidans strains recovered from cystic fibrosis patients, with P. aeruginosa and with Arthrobacter, suggesting that formation of hydroxylated PQS may be a common mechanism of inactivation
Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule
In Pseudomonas aeruginosa, quorum sensing (QS) regulates the production of secondary metabolites, many of which are antimicrobials that impact on polymicrobial community composition. Consequently, quenching QS modulates the environmental impact of P. aeruginosa. To identify bacteria capable of inactivating the QS signal molecule 2-heptyl-3- hydroxy-4(1H)-quinolone (PQS), a minimal medium containing PQS as the sole carbon source was used to enrich a Malaysian rainforest soil sample. This yielded an Achromobacter xylosoxidans strain (Q19) that inactivated PQS, yielding a new fluorescent compound (I-PQS) confirmed as PQS-derived using deuterated PQS. The I-PQS structure was elucidated using mass spectrometry and nuclear magnetic resonance spectroscopy as 2-heptyl-2-hydroxy-1,2-dihydroquinoline- 3,4-dione (HHQD). Achromobacter xylosoxidans Q19 oxidized PQS congeners with alkyl chains ranging from C1 to C5 and also N-methyl PQS, yielding the corresponding 2-hydroxy-1,2-dihydroquinoline-3,4- diones, but was unable to inactivate thePQSprecursor HHQ. This indicates that the hydroxyl group at position 3 in PQS is essential and that A. xylosoxidans inactivates PQS via a pathway involving the incorporation of oxygen at C2 of the heterocyclic ring. The conversion of PQS to HHQD also occurred on incubation with 12/17 A. xylosoxidans strains recovered from cystic fibrosis patients, with P. aeruginosa and with Arthrobacter, suggesting that formation of hydroxylated PQS may be a common mechanism of inactivation
The many faces of small B cell lymphomas with plasmacytic differentiation and the contribution of MYD88 testing
Plasmacytic differentiation may occur in almost all small B cell lymphomas (SBLs), although it varies from being uniformly present (as in lymphoplasmacytic lymphoma (LPL)) to very uncommon (as in mantle cell lymphomas (MCLs)). The discovery of MYD88 L265P mutations in the vast majority of LPLs has had a major impact on the study of these lymphomas. Review of the cases contributed to the 2014 European Association for Haematopathology/Society for Hematopathology slide workshop illustrated how mutational testing has helped refine the diagnostic criteria for LPL, emphasizing the importance of identifying a clonal monotonous lymphoplasmacytic population and highlighting how LPL can still be diagnosed with extensive nodal architectural effacement, very subtle plasmacytic differentiation, follicular colonization, or uncommon phenotypes such as CD5 or CD10 expression. MYD88 L265P mutations were found in 11/11 LPL cases versus only 2 of 28 other SBLs included in its differential diagnosis. Mutational testing also helped to exclude other cases that would have been considered LPL in the past. The workshop also highlighted how plasmacytic differentiation can occur in chronic lymphocytic leukemia/small lymphocytic lymphoma, follicular lymphoma, SOX11 negative MCL, and particularly in marginal zone lymphomas, all of which can cause diagnostic confusion with LPL. The cases also highlighted the difficulty in distinguishing lymphomas with marked plasmacytic differentiation from plasma cell neoplasms. Some SBLs with plasmacytic differentiation can be associated with amyloid, other immunoglobulin deposition, or crystal-storing histiocytosis, which may obscure the underlying neoplasm. Finally, although generally indolent, LPL may transform, with the workshop cases suggesting a role for TP53 abnormalities
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