335 research outputs found
Emergence of Gapped Bulk and Metallic Side Walls in the Zeroth Landau level in Dirac and Weyl semimetals
Recent transport experiments have revealed the activation of longitudinal
magnetoresistance of Weyl semimetals in the quantum limit, suggesting the
breakdown of chiral anomaly in a strong magnetic field. Here we provide a
general mechanism for gapping the zeroth chiral Landau levels applicable for
both Dirac and Weyl semimetals. Our result shows that the zeroth Landau levels
anticross when the magnetic axis is perpendicular to the Dirac/Weyl node
separation and when the inverse magnetic length is comparable to the
node separation scale . The induced bulk gap increases rapidly beyond
a threshold field in Weyl semimetals, but has no threshold and is non-monotonic
in Dirac systems due to the crossover between and
regions. We also find that the Dirac and possibly Weyl
systems host counterpropagating edge states between the zeroth Landau levels,
leading to a state with metallic side walls and zero Hall conductance.Comment: 8 pages, 4 figure
Heralded magnetism in non-Hermitian atomic systems
Quantum phase transitions are usually studied in terms of Hermitian
Hamiltonians. However, cold-atom experiments are intrinsically non-Hermitian
due to spontaneous decay. Here, we show that non-Hermitian systems exhibit
quantum phase transitions that are beyond the paradigm of Hermitian physics. We
consider the non-Hermitian XY model, which can be implemented using three-level
atoms with spontaneous decay. We exactly solve the model in one dimension and
show that there is a quantum phase transition from short-range order to
quasi-long-range order despite the absence of a continuous symmetry in the
Hamiltonian. The ordered phase has a frustrated spin pattern. The critical
exponent can be 1 or 1/2. Our results can be seen experimentally with
trapped ions, cavity QED, and atoms in optical lattices.Comment: 7 pages + appendi
Entanglement tongue and quantum synchronization of disordered oscillators
We study the synchronization of dissipatively-coupled van der Pol oscillators
in the quantum limit, when each oscillator is near its quantum ground state.
Two quantum oscillators with different frequencies exhibit an entanglement
tongue, which is the quantum analogue of an Arnold tongue. It means that the
oscillators are entangled in steady state when the coupling strength is greater
than a critical value, and the critical coupling increases with detuning. An
ensemble of many oscillators with random frequencies still exhibits a
synchronization phase transition in the quantum limit, and we analytically
calculate how the critical coupling depends on the frequency disorder. Our
results can be experimentally observed with trapped ions or neutral atoms.Comment: 11 pages, 5 figure
When chiral photons meet chiral fermions - Photoinduced anomalous Hall effects in Weyl semimetals
The Weyl semimetal is characterized by three-dimensional linear band touching
points called Weyl nodes. These nodes come in pairs with opposite chiralities.
We show that the coupling of circularly polarized photons with these chiral
electrons generates a Hall conductivity without any applied magnetic field in
the plane orthogonal to the light propagation. This phenomenon comes about
because with all three Pauli matrices exhausted to form the three-dimensional
linear dispersion, the Weyl nodes cannot be gapped. Rather, the net influence
of chiral photons is to shift the positions of the Weyl nodes. Interestingly,
the momentum shift is tightly correlated with the chirality of the node to
produce a net anomalous Hall signal. Application of our proposal to the
recently discovered TaAs family of Weyl semimetals leads to an
order-of-magnitude estimate of the photoinduced Hall conductivity which is
within the experimentally accessible range.Comment: 9 pages, 4 figure
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Development, validation, and application of HPLC method for quantification of antihyperuricemic compounds from Lippia nodiflora in rat plasma
AbstractAn HPLC method for simultaneous determination of arenarioside (1 ), verbascoside (2), 6-hydroxyluteolin (3), 6-hydroxyluteolin-7-O-glycoside (4), and nodifloretin (5) from Lippia nodiflora in rat plasma was developed and validated. The optimal chromatographic separation was achieved with a gradient mobile phase comprising 0.1% aqueous acetic acid and acetonitrile. The limit of detection was 78.1 ng/mL for 3 and 39.1 ng/mL for the other compounds (signal-to-noise ratio=3), whereas the limit of quantification was 312.5 ng/mL for 3 and 156.3 ng/mL for the other compounds (signal-to-noise ratio=12). The recovery values of compounds 1–5 ranged from 89.37–100.92%. Their accuracy values were between 96.48 and 105.81%, while their corresponding precision values were in the range of 0.75–9.06% for both intraday and inter-day analysis. The method was then applied in the first pharmacokinetic study of 1–5. Following intravenous administration, 1–5 were eliminated slowly from the body with a mean clearance value of 0.11, 0.13, 0.30, 0.09, and 0.23 L/kg h, respectively. Meanwhile, their peak plasma concentration upon oral administration was 8.97, 1.07, 1.06, 0.65, and 0.38 µg/mL, respectively. Compound 3 (5.97%) exhibited the highest absolute oral bioavailability value, followed by 1 (5.22%), 4 (3.13%), 2 (2.10%), and 5 (0.93%)
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Multi-targeting aurones with monoamine oxidase and amyloid-beta inhibitory activities: structure-activity relationship and translating multi-potency to neuroprotection
Previously, a series of aurones bearing amine and carbamate functionalities was synthesized and evaluated for their cholinesterase inhibitory activity and drug-like attributes. In the present study, these aurones were evaluated for their multi-targeting properties in two Alzheimer’s disease (AD)-related activities namely, monoamine oxidase (MAO) and amyloid-beta (Aβ) inhibition. Evaluation of the aurones for MAO inhibitory activity disclosed several potent selective inhibitors of MAO-B, particularly those with 6-methoxyl group attached at ring A. Of the different amine moieties attached as side chains, pyrrolidine-bearing aurones were prominent as represented by 2-2, the most potent inhibitor. Evaluation on the Aβ aggregation inhibition identified 4-3 as the best inhibitor with a percentage inhibition comparable
to that of a known Aβ inhibitor curcumin. Examination on the neuroprotective ability of the more drug-like aurone 4-3 in two Caenorhabditis elegans neurodegeneration models showed 4-3 to protect the nematodes against both Aβ- and 6-hydroxydopamine-induced toxicities. These new activities further support 4-3 as a promising lead to develop the aurones as potential multipotent agents for neurodegenerative diseases
Photocurrents in Weyl semimetals
The generation of photocurrent in an ideal two-dimensional Dirac spectrum is symmetry forbidden. In sharp contrast, we show that three-dimensional Weyl semimetals can generically support significant photocurrents due to the combination of inversion symmetry breaking and finite tilts of the Weyl spectra. Symmetry properties, chirality relations, and various dependencies of this photovoltaic effect on the system and the light source are explored in detail. Our results suggest that noncentrosymmetric Weyl materials can be advantageously applied to room temperature detections of mid- and far-infrared radiations.United States. Department of Energy (DE-FG02-03-ER46076
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