360 research outputs found

    Degrees of Freedom of Full-Duplex Multiantenna Cellular Networks

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    We study the degrees of freedom (DoF) of cellular networks in which a full duplex (FD) base station (BS) equipped with multiple transmit and receive antennas communicates with multiple mobile users. We consider two different scenarios. In the first scenario, we study the case when half duplex (HD) users, partitioned to either the uplink (UL) set or the downlink (DL) set, simultaneously communicate with the FD BS. In the second scenario, we study the case when FD users simultaneously communicate UL and DL data with the FD BS. Unlike conventional HD only systems, inter-user interference (within the cell) may severely limit the DoF, and must be carefully taken into account. With the goal of providing theoretical guidelines for designing such FD systems, we completely characterize the sum DoF of each of the two different FD cellular networks by developing an achievable scheme and obtaining a matching upper bound. The key idea of the proposed scheme is to carefully allocate UL and DL information streams using interference alignment and beamforming techniques. By comparing the DoFs of the considered FD systems with those of the conventional HD systems, we establish the DoF gain by enabling FD operation in various configurations. As a consequence of the result, we show that the DoF can approach the two-fold gain over the HD systems when the number of users becomes large enough as compared to the number of antennas at the BS.Comment: 21 pages, 16 figures, a shorter version of this paper has been submitted to the IEEE International Symposium on Information Theory (ISIT) 201

    2D material platform for overcoming the amplitude-phase tradeoff in ring modulators

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    Compact, high-speed electro-optic phase modulators play a vital role in various large-scale applications including phased arrays, quantum and neural networks, and optical communication links. Conventional phase modulators suffer from a fundamental tradeoff between device length and optical loss that limits their scaling capabilities. High-finesse ring resonators have been traditionally used as compact intensity modulators, but their use for phase modulation have been limited due to the high insertion loss associated with the phase change. Here, we show that high-finesse resonators can achieve a strong phase change with low insertion loss by simultaneous modulation of the real and imaginary parts of the refractive index, to the same extent i.e. ΔnΔk1\frac{\Delta n}{\Delta k} \sim 1. To implement this strategy, we utilize a hybrid platform that combines a low-loss SiN ring resonator with electro-absorptive graphene (Gr) and electro-refractive WSe2_2. We achieve a phase modulation efficiency (Vπ2Lπ2V_{\frac{\pi}{2}} \cdot L_{\frac{\pi}{2}}) of 0.045 V \cdot cm with an insertion loss (ILπ2_{\frac{\pi}{2}}) of 4.7 dB for a phase change of π2\frac{\pi}{2} radians, in a 25 μ\mum long Gr-Al2_2O3_3-WSe2_2 capacitor embedded on a SiN ring of 50 μ\mum radius. We find that our Gr-Al2_2O3_3-WSe2_2 capacitor can support an electro-optic bandwidth of 14.9 ±\pm 0.1 GHz. We further show that the Vπ2Lπ2V_{\frac{\pi}{2}} \cdot L_{\frac{\pi}{2}} of our SiN-2D platform is at least an order of magnitude lower than that of electro-optic phase modulators based on silicon, III-V on silicon, graphene on silicon and lithium niobate. This SiN-2D hybrid platform provides the impetus to design compact and high-speed reconfigurable circuits with graphene and transition metal dichalcogenide (TMD) monolayers that can enable large-scale photonic systems

    Ethylene Inhibitors Enhance Shoot Organogenesis of Gloxinia ( Sinningia speciosa

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    Shoot organogenesis and plant regeneration in Sinningia speciosa were improved using ethylene inhibitors. The leaf explants were cultured on initial shoot regeneration media (MS media with BAP at 2 mg/L + NAA at 0.1 mg/L) supplemented with different concentrations of aminoethoxyvinylglycine (AVG), cobalt chloride (CoCl2), and silver thiosulphate (STS). The addition of AVG, CoCl2, and STS significantly improved the regeneration frequency giving higher shoots per explant and longer shoot length. The highest shoot growth was found when STS at 5 mg/L was incorporated with generation medium, performing highest regeneration frequency with highest number of shoots. This treatment (STS at 5 mg/L) produced 40% more shoots per explant compared to control followed by STS at 10 mg/L with increasing 37% more shoots compared to control. In the cases of AVG and CoCl2 the highest shoot number per explant was found at 1 mg/L. Treated with AVG and CoCl2 at 1 mg/L increased shoot number by 16 and 12%, respectively, compared to control. Ethylene inhibitors could be used as a possible micropropagation and plant transformation protocol in S. speciosa for plant regenerations

    Incidental thyroid lesions detected by FDG-PET/CT: prevalence and risk of thyroid cancer

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    <p>Abstract</p> <p>Background</p> <p>Incidentally found thyroid lesions are frequently detected in patients undergoing FDG-PET/CT. The aim of this study was to investigate the prevalence of incidentally found thyroid lesions in patients undergoing FDG-PET/CT and determine the risk for thyroid cancer.</p> <p>Methods</p> <p>FDG-PET/CT was performed on 3,379 patients for evaluation of suspected or known cancer or cancer screening without any history of thyroid cancer between November 2003 and December 2005. Medical records related to the FDG-PET/CT findings including maximum SUV(SUV<sub>max</sub>) and pattern of FDG uptake, US findings, FNA, histopathology received by operation were reviewed retrospectively.</p> <p>Results</p> <p>Two hundred eighty five patients (8.4%) were identified to have FDG uptake on FDG-PET/CT. 99 patients with focal or diffuse FDG uptake underwent further evaluation. The cancer risk of incidentally found thyroid lesions on FDG-PET/CT was 23.2% (22/99) and the cancer risks associated with focal and diffuse FDG uptake were 30.9% and 6.4%. There was a significant difference in the SUV<sub>max </sub>between the benign and malignant nodules (3.35 ± 1.69 vs. 6.64 ± 4.12; P < 0.001). There was a significant correlation between the SUV<sub>max </sub>and the size of the cancer.</p> <p>Conclusion</p> <p>The results of this study suggest that incidentally found thyroid lesions by FDG-PET/CT, especially a focal FDG uptake and a high SUV, have a high risk of thyroid malignancy. Further diagnostic work-up is needed in these cases.</p

    Enhanced interlayer neutral excitons and trions in trilayer van der Waals heterostructures

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    Vertically stacked van der Waals heterostructures constitute a promising platform for providing tailored band alignment with enhanced excitonic systems. Here we report observations of neutral and charged interlayer excitons in trilayer WSe2-MoSe2-WSe2 van der Waals heterostructures and their dynamics. The addition of a WSe2 layer in the trilayer leads to significantly higher photoluminescence quantum yields and tunable spectral resonance compared to its bilayer heterostructures at cryogenic temperatures. The observed enhancement in the photoluminescence quantum yield is due to significantly larger electron-hole overlap and higher light absorbance in the trilayer heterostructure, supported via first-principle pseudopotential calculations based on spin-polarized density functional theory. We further uncover the temperature- and power-dependence, as well as time-resolved photoluminescence of the trilayer heterostructure interlayer neutral excitons and trions. Our study elucidates the prospects of manipulating light emission from interlayer excitons and designing atomic heterostructures from first-principles for optoelectronics.Comment: 25 pages, 5 figures(Maintext). 9 pages, 7 figures(Supplementary Information). - Accepted for publication in npg: 2D materials and applications and reformatted to its standard. - Updated co-authors and references. - Title and abstract are modified for clarity. - Errors have been corrected, npg: 2D materials and applications (2018

    Phospholipase C-γ as a Potential Therapeutic Target for Graves’ Orbitopathy

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    Background Phospholipase C-γ (PLC-γ) plays a crucial role in immune responses and is related to the pathogenesis of various inflammatory disorders. In this study, we investigated the role of PLC-γ and the therapeutic effect of the PLC-specific inhibitor U73122 using orbital fibroblasts from patients with Graves’ orbitopathy (GO). Methods The expression of phospholipase C gamma 1 (PLCG1) and phospholipase C gamma 2 (PLCG2) was evaluated using polymerase chain reaction in GO and normal orbital tissues/fibroblasts. The primary cultures of orbital fibroblasts were treated with non-toxic concentrations of U73122 with or without interleukin (IL)-1β to determine its therapeutic efficacy. The proinflammatory cytokine levels and activation of downstream signaling molecules were determined using Western blotting. Results PLCG1 and PLCG2 mRNA expression was significantly higher in GO orbital tissues than in controls (P<0.05). PLCG1 and PLCG2 mRNA expression was significantly increased (P<0.05) in IL-1β, tumor necrosis factor-α, and a cluster of differentiation 40 ligand-stimulated GO fibroblasts. U73122 significantly inhibited the IL-1β-induced expression of proinflammatory molecules, including IL-6, IL-8, monocyte chemoattractant protein-1, cyclooxygenase-2, and intercellular adhesion molecule-1 (ICAM-1), and phosphorylated protein kinase B (p-Akt) and p38 (p-p38) kinase in GO fibroblasts, whereas it inhibited IL-6, IL-8, and ICAM-1, and p-Akt and c-Jun N-terminal kinase (p-JNK) in normal fibroblasts (P<0.05). Conclusion PLC-γ-inhibiting U73122 suppressed the production of proinflammatory cytokines and the phosphorylation of Akt and p38 kinase in GO fibroblasts. This study indicates the implications of PLC-γ in GO pathogenesis and its potential as a therapeutic target for GO
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