17 research outputs found
Phase diagram and critical properties in the Polyakov--Nambu--Jona-Lasinio model
We investigate the phase diagram of the so-called
Polyakov--Nambu--Jona-Lasinio model at finite temperature and nonzero chemical
potential with three quark flavours. Chiral and deconfinement phase transitions
are discussed, and the relevant order-like parameters are analyzed. The results
are compared with simple thermodynamic expectations and lattice data. A special
attention is payed to the critical end point: as the strength of the
flavour-mixing interaction becomes weaker, the critical end point moves to low
temperatures and can even disappear.Comment: Talk given at the 9th International Conference on Quark Confinement
and the Hadron Spectrum - QCHS IX, Madrid, Spain, 30 August - September 201
Magnetic resonance lung function – a breakthrough for lung imaging and functional assessment? A phantom study and clinical trial
BACKGROUND: Chronic lung diseases are a major issue in public health. A serial pulmonary assessment using imaging techniques free of ionizing radiation and which provides early information on local function impairment would therefore be a considerably important development. Magnetic resonance imaging (MRI) is a powerful tool for the static and dynamic imaging of many organs. Its application in lung imaging however, has been limited due to the low water content of the lung and the artefacts evident at air-tissue interfaces. Many attempts have been made to visualize local ventilation using the inhalation of hyperpolarized gases or gadolinium aerosol responding to MRI. None of these methods are applicable for broad clinical use as they require specific equipment. METHODS: We have shown previously that low-field MRI can be used for static imaging of the lung. Here we show that mathematical processing of data derived from serial MRI scans during the respiratory cycle produces good quality images of local ventilation without any contrast agent. A phantom study and investigations in 85 patients were performed. RESULTS: The phantom study proved our theoretical considerations. In 99 patient investigations good correlation (r = 0.8; p ≤ 0.001) was seen for pulmonary function tests and MR ventilation measurements. Small ventilation defects were visualized. CONCLUSION: With this method, ventilation defects can be diagnosed long before any imaging or pulmonary function test will indicate disease. This surprisingly simple approach could easily be incorporated in clinical routine and may be a breakthrough for lung imaging and functional assessment