Evolution of antibody responses to <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i> SGE in military personnel.

<p>The figure presents individual IgG responses (ΔOD) to <i>Ae</i>. <i>aegypti</i> (A) and <i>Ae</i>. <i>polynesiensis</i> (B) SGE of French military personnel (n = 13) assigned in Tahiti island (French Polynesia). Blood from the same individual was sampled two weeks after arrival and one year later (paired data). Each triangle or dot represents an individual serum and the horizontal bar indicates the median value. The dotted lines correspond to the positivity thresholds calculated from the cohort of metropolitan French residents (0.16 and 0.13 for <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i>, respectively). Percentages of responders are shown above each plot. The non-parametric Wilcoxon test was used to compare the paired groups.</p

Antibody responses to <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i> SGE from cohorts from different contexts of exposure.

<p>The figure presents the individual IgG responses (ΔOD) against <i>Ae</i>. <i>aegypti</i> (A) and <i>Ae</i>. <i>polynesiensis</i> (B) SGE of residents from Martinique (n = 46), New-Caledonia (n = 19), Bolivia (n = 30) and Reunion (n = 33). The horizontal bars indicate the median value in each group and the dotted lines correspond to the positivity thresholds calculated from the cohort of metropolitan French residents. The percentage of responders in each cohort is shown above the plot. Residents from Martinique, New Caledonia and Bolivia, are typically exposed to <i>Ae</i>. <i>aegypti</i> bites. In Reunion island, <i>Ae</i>. <i>albopictus</i> is the main <i>Aedes</i> species while <i>Ae</i>. <i>aegypti</i> is cryptic. <i>Ae</i>. <i>polynesiensis</i> is not present in these islands or countries.</p

Antibody responses to <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i> SGE in French Polynesian residents.

<p>The figure presents the individual IgG responses (ΔOD) against <i>Ae</i>. <i>aegypti</i> (A) and <i>Ae</i>. <i>polynesiensis</i> (B) SGE in metropolitan France (n = 66) and in Tahiti and Moorea islands (French Polynesia, n = 47) residents. Each triangle or dot represents an individual sample and the horizontal bar indicates the median value. The dotted lines correspond to the positivity thresholds calculated from the cohort of metropolitan French residents, not exposed to these <i>Aedes</i> species (0.16 for <i>Ae</i>. <i>aegypti</i> and 0.13 for <i>Ae</i>. <i>polynesiensis</i>). The percentage of responders (positive samples) in the Tahiti-Moorea cohort is shown above the plot. The non-parametric Mann-Whitney test was used to compare groups.</p

<i>A. polynesiensis</i> population dynamics.

<p>Collection data is shown for the A) Tiano (ANO), B) Horea (HOR) and C) Toamaro (TOA) study sites, as measured by BG trap collections of adult females. Lines show moving averages across four collection periods. Time is shown as the relative week number, with ‘Week 0’ as the start of releases. The grey shaded box indicates the release period on TOA, with CP releases ending on Week 30.</p

Egg hatch resulting from intra- and inter-specific crosses.

*<p>Interspecific crosses consist of CP males combined with virgin female.</p><p><i>A. polynesiensis</i>, <i>A. aegypti</i> and <i>A. albopictus</i>.</p

Percent females that produced hatching egg broods at a no-release site (HOR) and the site receiving CP male releases (TOA).

<p>The asterisk indicates a significant difference X² (1, N = 887) = 38.18, p<0.0001.</p

Box plots of delta values used in the BACIPS statistical analysis.

<p>Each of the three possible combinations of site pairs is shown. For each pair, delta values are of collections within the thirty-week period immediately prior to the start of CP male release (‘Before’) and the thirty-week period during CP male release (‘During’). Delta values are calculated as the difference between population numbers at the sites, with population number indicated as ln(<i>Female Number</i> +1). Sites are the release site Toamaro (TOA), which received releases of CP males, and the two no-release sites Tiano (ANO) and Horea (HOR), which did not receive CP male releases. Asterisks indicate a significant difference in comparisons of the ‘Before’ and ‘During’ release periods (p<0.0001).</p

Negative-to-negative test concordance in community survey.

<p>Note: Fractions represent the number of negative results for each test (numerator) out of those that were negative by the index test (denominator). The results are of the form: proportion (%). The number of negative index tests (denominator) changes by column because it only includes specimens with valid results by the comparison test (numerator).</p><p>*Based on 10 µl blood specimen.</p

Number of <i>valid</i>^* tests performed on participants specimens.

<p>*Note: This does not include the 7,481 invalid or indeterminate tests.</p

Prevalence of positive results by test and country.

<p>Prevalence of positive results by test and country.</p