1,673 research outputs found

    Phenomenology Tools on Cloud Infrastructures using OpenStack

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    We present a new environment for computations in particle physics phenomenology employing recent developments in cloud computing. On this environment users can create and manage "virtual" machines on which the phenomenology codes/tools can be deployed easily in an automated way. We analyze the performance of this environment based on "virtual" machines versus the utilization of "real" physical hardware. In this way we provide a qualitative result for the influence of the host operating system on the performance of a representative set of applications for phenomenology calculations.Comment: 25 pages, 12 figures; information on memory usage included, as well as minor modifications. Version to appear in EPJ

    Phenotypic characterization of oral streptococci by classical methods

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    The phenotypic characteristics of 215 strains of oral streptococci were compared on the basis of the results of sorbitol, raffinose and trehalose fermentation, ammonium from arginine production, aesculin hydrolysis, H2O2 production, susceptibility to 2 U bacitracin, and growth in 4% NaCl solution. Eleven different species were identified. Among the most noteworthy findings were the low number of H2O2-producing strains of Streptococcus sobrinus, the effective discrimination between Streptococcus sanguis and Streptococcus mitis on the basis of raffinose fermentation, and the phenotypic similarity between Streptococcus oralis and the former mutans group. To avoid the creation of new species, the term biotype is proposed to designate phenotypically distinct organisms which do not qualify as different species

    A model allowing for the influence of geometry and stress in the assessment of fatigue data

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    Usually, the Wohler field of a material is obtained from fatigue lifetime data resulting from testing specimens of reduced size in the laboratory. This basic information finds subsequent application in lifetime prediction of larger structural and mechanical components. Thus, an important question arises: how can the S-N field be transformed into an ideal one referred to a characteristic size (length, area or volume) subjected to a constant stress distribution in order to achieve a safe structural integrity design? In this work, the influence of specimen geometry and variable stress state on the fatigue lifetime distribution for constant amplitude fatigue tests is investigated. An experimental program has been carried out with unnotched specimens of nominally the same material but differing in length, diameter, and shape. The experimental data is fitted to a newly developed fatigue model, capable of describing the S-N-field in a probabilistic manner accounting for both the specimen geometry and the variable stress state of the specimens. As the estimated Wohler field is referred to an elemental surface, loaded by a constant stress level Ds, the extrapolation of the fatigue resistance to different specimen geometries is possible. Additionally, problems encountered due to scatter of the material properties are discussed

    The role of impulsivity in dropout from treatment for cigarette smoking

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    AbstractImpulsivity is a variable that has been associated with drug use. This study analyzes impulsivity from two different paradigms, one considering it as a trait and the other based on its behavioral correlates, such as disinhibition and impulsive decision-making in the treatment prognosis (maintain abstinence, relapse and dropout) of smokers after outpatient treatment. The participants in the study were 113 smokers who requested treatment for nicotine addiction. They were assigned to three groups according to whether or not they remained abstinent one month after beginning treatment; thus, group 1 was abstinent, group 2 had relapsed, and group 3 had dropped out of treatment. The participants filled out the Semi-structured Interview for Smokers, the Fargerström Test for Nicotine Dependence, the Temperament and Character Inventory-Revised (TCI-R) and the Delay Discounting Task (DDT). The Delay Discounting variable presents lower scores in the dropout group than in the relapse and abstinent groups, with the highest scores in the relapse group. Differences were also found on the Harm Avoidance (HA) variable, with lower scores in the dropout group compared to the relapse group. The importance of these results lies in the consideration of the smoker’s personality profile in order to prevent both dropout and relapse

    General Information About the Design of Smart Grids in Universities

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    Until recently, the dominant paradigm in the electrification consisted of universal service and its centralization, and for loor modern times think of the power grid of the future where a qualitative and radical leap is required because of the need to manage better energy resources, promote environmental protection and meet the increasingly demanding requirements of quality of service. A power distribution network becomes intelligent acquiring data, communicating, processing information and exercising control through a feedback that allows you to adjust to changes that may arise in actual operation. Ecuador aimed at energy efficiency through smart grids, which allow the dealer to maintain absolute monitoring of energy flow and the elements of the power grid. Thus, it is possible that service companies can efficiently manage their assets and the end user to manage consumption rationally, requiring to enhance the energy efficiency of power grids, one management timely and efficient energy

    Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis

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    Indexación: Scopus.Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring. Previous studies have shown that maternal hypothyroidism increases the severity of experimental autoimmune encephalomyelitis (EAE), an autoimmune disease model for multiple sclerosis (MS). Here, we analyzed the immune response after EAE induction in the adult offspring gestated in Hpx. Mice gestated in Hpx showed an early appearance of EAE symptoms and the increase of all parameters of the disease such as: the pathological score, spinal cord demyelination, and immune cell infiltration in comparison to the adult offspring gestated in euthyroidism. Isolated CD4+CD25+ T cells from spleen of the offspring gestated in Hpx that suffer EAE showed reduced capacity to suppress proliferation of effector T cells (TEff) after being stimulated with anti-CD3 and anti-CD28 antibodies. Moreover, adoptive transfer experiments of CD4+CD25+ T cells from the offspring gestated in Hpx suffering EAE to mice that were induced with EAE showed that the receptor mice suffer more intense EAE pathological score. Even though, no significant differences were detected in the frequency of Treg cells and IL-10 content in the blood, spleen, and brain between mice gestated in Hpx or euthyroidism, T cells CD4+CD25+ from spleen have reduced capacity to differentiate in vitro to Treg and to produce IL-10. Thus, our data support the notion that maternal Hpx can imprint the immune response of the offspring suffering EAE probably due to a reduced capacity to trigger suppression. Such "imprints" on the immune system could contribute to explaining as to why adult offspring gestated in Hpx suffer earlier and more intense EAE. © 2018 Haensgen, Albornoz, Opazo, Bugueño, Jara Fernández, Binzberger, Rivero-Castillo, Venegas Salas, Simon, Cabello-Verrugio, Elorza, Kalergis, Bueno and Riedel.https://www.frontiersin.org/articles/10.3389/fimmu.2018.01257/ful
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