194 research outputs found

    Buckling of built-up columns of pultruded fiber-reinforced polymer C-sections

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    This paper presents the test results of an experimental investigation to evaluate the buckling behavior of built-up columns of pultruded profiles, subjected to axial compression. Specimens are assembled by using four (off the shelf) channel shaped profiles of E-glass fiber-reinforced polymer (FRP), having similar detailing to strut members in a large FRP structure that was executed in 2009 to start the restoration of the Santa Maria Paganica church in L’Aquila, Italy. This church had partially collapsed walls and no roof after the April 6, 2009, earthquake of 6.3 magnitude. A total of six columns are characterized with two different configurations for the bolted connections joining the channel sections into a built-up strut. Test results are discussed and a comparison is made with closed-form equation predictions for flexural buckling resistance, with buckling resistance values established from both eigenvalue and geometric nonlinear finite element analyses. Results show that there is a significant role played by the end loading condition, the composite action, and imperfections. Simple closed-form equations overestimate the flexural buckling strength, whereas the resistance provided by the nonlinear analysis provides a reasonably reliable numerical approach to establishing the actual buckling behavior

    The pitfalls of inferring virus-virus interactions from co-detection prevalence data: application to influenza and SARS-CoV-2

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    There is growing experimental evidence that many respiratory viruses—including influenza and SARS-CoV-2—can interact, such that their epidemiological dynamics may not be independent. To assess these interactions, standard statistical tests of independence suggest that the prevalence ratio—defined as the ratio of co-infection prevalence to the product of single-infection prevalences—should equal unity for non-interacting pathogens. As a result, earlier epidemiological studies aimed to estimate the prevalence ratio from co-detection prevalence data, under the assumption that deviations from unity implied interaction. To examine the validity of this assumption, we designed a simulation study that built on a broadly applicable epidemiological model of co-circulation of two emerging or seasonal respiratory viruses. By focusing on the pair influenza–SARS-CoV-2, we first demonstrate that the prevalence ratio systematically underestimates the strength of interaction, and can even misclassify antagonistic or synergistic interactions that persist after clearance of infection. In a global sensitivity analysis, we further identify properties of viral infection—such as a high reproduction number or a short infectious period—that blur the interaction inferred from the prevalence ratio. Altogether, our results suggest that ecological or epidemiological studies based on co-detection prevalence data provide a poor guide to assess interactions among respiratory viruses

    Estimating the impact of influenza on the epidemiological dynamics of SARS-CoV-2

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    As in past pandemics, co-circulating pathogens may play a role in the epidemiology of coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In particular, experimental evidence indicates that influenza infection can up-regulate the expression of ACE2—the receptor of SARS-CoV-2 in human cells—and facilitate SARS-CoV-2 infection. Here we hypothesized that influenza impacted the epidemiology of SARS-CoV-2 during the early 2020 epidemic of COVID-19 in Europe. To test this hypothesis, we developed a population-based model of SARS-CoV-2 transmission and of COVID-19 mortality, which simultaneously incorporated the impact of non-pharmaceutical control measures and of influenza on the epidemiological dynamics of SARS-CoV-2. Using statistical inference methods based on iterated filtering, we confronted this model with mortality incidence data in four European countries (Belgium, Italy, Norway, and Spain) to systematically test a range of assumptions about the impact of influenza. We found consistent evidence for a 1.8–3.4-fold (uncertainty range across countries: 1.1 to 5.0) average population-level increase in SARS-CoV-2 transmission associated with influenza during the period of co-circulation. These estimates remained robust to a variety of alternative assumptions regarding the epidemiological traits of SARS-CoV-2 and the modeled impact of control measures. Although further confirmatory evidence is required, our results suggest that influenza could facilitate the spread and hamper effective control of SARS-CoV-2. More generally, they highlight the possible role of co-circulating pathogens in the epidemiology of COVID-19

    Skewed contributions of individual trees to indirect nature experiences

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    This is the author accepted manuscript. Final version available from Elsevier via the DOI in this record.Exposure to nature is associated with a broad range of benefits to human health. Whilst there has been exploration of how these experiences vary amongst people, the converse – how different individual organisms contribute to human nature experiences – has largely been overlooked. The most common way that people experience nature occurs indirectly, when they are in a room with a natural view. Here, we estimate variation in how individual trees provide indirect nature experiences in an urban human population. As a proxy for its contribution towards indirect nature experiences, within an extended urban area in southern England, UK (n = 612,920) we calculated the number of buildings with line of sight to each tree. We then modelled each tree’s contribution towards these experiences against potential predictors, namely tree height, land ownership, social deprivation, while controlling for human population density. We demonstrate that a small number of trees contribute disproportionately towards indirect nature experiences, with individual trees in socio-economically deprived high density housing falling within the viewscape of significantly more buildings. Further, trees in private gardens were generally more important for providing indirect nature experiences than those in public green spaces. This novel study demonstrates the skewed contribution of different organisms to human population indirect nature experiences. This approach can be applied more broadly to understand how individual organisms provide indirect, incidental and intentional nature experiences. Understanding the ecology behind human nature experiences is an important step towards linking urban design and policy for maximising the health benefits from nature.Natural Environment Research Council (NERC

    Improving models of urban greenspace: from vegetation surface cover to volumetric survey, using waveform laser scanning

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    This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.1 Urban greenspace has a major impact on human health and quality of life, and thus the way in which such green infrastructure is constructed, managed and maintained is of critical importance. A range of studies have demonstrated the relationship between the areal coverage and distribution of vegetation and the provision of multiple urban ecosystem services. It is not known how sensitive findings are to the spatial resolution of the underlying data relative to the grain size of urban land cover heterogeneity. Moreover, little is known about the three-dimensional (3D) structure of urban vegetation and delivery of services, and addressing such questions is limited by the availability of data describing canopy structure from the tree tops to the ground. 2 Waveform airborne laser scanning (lidar) offers a new way of capturing 3D data describing vegetation structure. We generated voxels (volumetric pixels) from waveform lidar (1.5 m resolution), differentiated vegetation layers using height as a determinant, and computed statistics on surface cover, volume and volume density per stratum. We then used a range of widely available remote sensing products with varying spatial resolution (1m to 100m) to map the same greenspace, and compared results to those from the waveform lidar survey. 3 We focused on data from three urban zones in the UK with distinct patterns of vegetation cover. We found -3%, +7.5% and +26.1% differences in green surface cover compared with, respectively, town planning maps (< 10 m resolution), national land cover maps (25 m) and European land cover maps (100 m). There were differences of -59.1%, +12.4% and -2.4% in tree cover compared with global (30 m resolution), European (25 m) and national (1 m) estimates. Waveform lidar captured sub-canopy structure and detected empty spaces in the understorey which contributed a 16% bias in the total green volume derived from non-waveform lidar observations. 4 We conclude that waveform lidar has a key role to play in estimating important quantitative metrics of urban green infrastructure, which is important because urban greenspace is highly fragmented and shows high levels of spatial and volumetric heterogeneity

    BZ Cam during its 1999/2000 optical low state

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    We report optical observations of the VY Scl star BZ Cam during its previous optical low state in 1999/2000. We find drastic variations in the line profiles. Narrow-band imaging observations show that its nebula extends farther than previously known and seems to be composed of two components. We determine the [OIII] line intensity of BZ Cam's nebula to 4.8 * 10^-13 erg/cm^2/s. We discover a proper motion of BZ Cam of 25+-2 mas/yr which together with the systemic radial velocity yields a space velocity of 125 km/s. We re-interpret the nebula as being photo-ionized by hypothesized transient, luminous, supersoft X-ray emission during optical low states, and shaped by the transverse motion of BZ Cam.Comment: 8 pages with aa.sty, 8 figures, to appear in A&

    Electron transport in crystalline PCBM-like fullerene derivatives: a comparative computational study

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    We present an extensive study of electron transport (ET) in several crystal forms of phenyl-C61-butyric acid methyl ester (PCBM) and 1-thienyl-C61-butyric acid methyl ester (ThCBM) fullerene derivatives. Our calculations are based on a localized representation of the electronic states. Orbital couplings, site energies and reorganization energies have been calculated using various density functional and semi-empirical techniques and used within the Landau–Zener, Marcus and Marcus–Levich–Jortner expressions to evaluate electron transfer rates. Electron mobilities have been then estimated by kinetic Monte Carlo (KMC) simulations. The adiabaticity of electron transfer directions within the different crystal structures has also been verified using the Landau–Zener expression. Finally, the role of low energy virtual orbitals of the fullerene molecules has been investigated using charge transport networks of increasing complexities. Our results show that these molecules may form one-, two- or three-dimensional percolation networks and that their higher energy orbitals often participate in ET. The highest mobility values were obtained for the crystal structure of ThCBM and are comparable to experimental values

    The X-ray emission from Nova V382 Velorum: II. The super-soft component observed with BeppoSAX

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    Nova Velorum 1999 (V382 Vel) was observed by BeppoSAX 6 months after optical maximum and was detected as a bright X-ray supersoft source, with a count rate 3.454+-0.002 cts/s in the LECS. It was the softest and most luminous supersoft source observed with this instrument. The flux in the 0.1-0.7 keV range was not constant during the observation. It dropped by a factor of 2 in less than 1.5 hour and then was faint for at least 15 minutes, without significant spectral changes. The observed spectrum is not well fit with atmospheric models of a hot, hydrogen burning white dwarf. This is due mainly to a supersoft excess in the range 0.1-0.2 keV, but the fit can be significantly improved at higher energy if at least one emission feature is superimposed. We suggest that a ``pseudocontinuum'' was detected, consisting of emission lines in the supersoft X-ray range superimposed on the thermal continuum of a white dwarf atmosphere. As a result, an accurate determination of the effective temperature and gravity of the white dwarf at this post-outburst stage is not possible.Comment: To appear in MNRA
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