Nonadditive entropy and nonextensive statistical mechanics - Some central concepts and recent applications

We briefly review central concepts concerning nonextensive statistical mechanics, based on the nonadditive entropy $S_q=k\frac{1-\sum_{i}p_i^q}{q-1} (q \in {\cal R}; S_1=-k\sum_{i}p_i \ln p_i)$. Among others, we focus on possible realizations of the $q$-generalized Central Limit Theorem, including at the edge of chaos of the logistic map, and for quasi-stationary states of many-body long-range-interacting Hamiltonian systems.Comment: 15 pages, 9 figs., to appear in Journal of Physics: Conf.Series (IOP, 2010

Comparison of three control drive systems for interior permanent magnet synchronous motors

In a previous paper, we proposed a control strategy for interior permanent synchronous motors, which takes into account also the reduction of the motor power losses. The novelty of the suggested approach is that it takes into consideration the variations of all the motor parameters that have an influence on its efficiency. In order to verifyon the field the effectiveness of this new method, we implemented the proposed loss model algorithm in a control drive system and compared its performances, in terms of energy losses with respect to other conventional techniques

On the classical capacity of quantum Gaussian channels

The set of quantum Gaussian channels acting on one bosonic mode can be classified according to the action of the group of Gaussian unitaries. We look for bounds on the classical capacity for channels belonging to such a classification. Lower bounds can be efficiently calculated by restricting to Gaussian encodings, for which we provide analytical expressions.Comment: 10 pages, IOP style. v2: minor corrections, close to the published versio

Thermostatistics in the neighborhood of the π\pi-mode solution for the Fermi-Pasta-Ulam β\beta system: from weak to strong chaos

We consider a $\pi$-mode solution of the Fermi-Pasta-Ulam $\beta$ system. By perturbing it, we study the system as a function of the energy density from a regime where the solution is stable to a regime, where is unstable, first weakly and then strongly chaotic. We introduce, as indicator of stochasticity, the ratio $\rho$ (when is defined) between the second and the first moment of a given probability distribution. We will show numerically that the transition between weak and strong chaos can be interpreted as the symmetry breaking of a set of suitable dynamical variables. Moreover, we show that in the region of weak chaos there is numerical evidence that the thermostatistic is governed by the Tsallis distribution.Comment: 15 pages, 5 figure

Comparative Detailed Analysis of a 7-Level Cascaded H-Bridge Inverter in Symmetric and Asymmetric Configurations

This paper discusses the advantages of asymmetric multilevel inverters over traditional inverters and presents a comparative analysis between symmetric and asymmetric cascaded H-bridge multilevel topologies. The use of multilevel inverters is gaining importance in sectors such as electric transportation and renewable energy integration due to their ability to generate high-quality waveforms with lower harmonic content. However, the cost associated with multilevel inverters is a challenge due to the large number of required components. The paper focuses on a single-phase 7-level binary asymmetrical Cascaded H-Bridge Multilevel Inverter (CHBMIs) and compares its performance with the symmetrical counterpart in terms of both harmonic content and total harmonic distortion. In addition, the percentage of power absorbed by both bridges of the asymmetric converter is also analyzed. The results presented in this work show demonstrate the effectiveness of the proposed asymmetrical converter

Different gene expression modulation is the major effect fue to shear stress and stent application in huvecs model: preliminary results

Although it is known that disturbed shear stress may cause endothelial damage, the mechanism by which a stent procedure may affect the endothelium is not yet fully clarify. We present the preliminary data on gene expression analysis of human endothelial cells in a laminar flow bioreactor (LFB) system submitted to different physical (flow changes) and/or mechanical (stent application) stimuli. Our preliminary results show that low shear stress together with stent procedure are the experimental conditions that mainly modulate the highest number of genes in human endothelial model. Those genes belong to pathways specifically involved in the endothelial dysfunctio

High density of tryptase-positive mast cells in human colorectal cancer: a poor prognostic factor related to protease-activated receptor 2 expression

Tryptase(+) mast cells (MCs), abundant in the invasive front of tumours, contribute to tissue remodelling. Indeed, protease-activated receptor- 2 (PAR-2) activation by MC-tryptase is considered an oncogenic event in colorectal cancer (CRC). Recently, we have suggested NHERF1 as a potential new marker in CRC. In this study, we aimed to determine the distribution of tryptase(+) MCs and PAR-2 and to examine the relationship between PAR-2 and NHERF1, investigating their reputed usefulness as tumour markers. We studied a cohort of 115 CRC specimens including primary cancer (C) and adjacent normal mucosa (NM) by immunohistochemical double staining, analyzing the protein expression of MC-tryptase, PAR-2 and cytoplasmic NHERF1. MC density was higher in NM than in C. Tumours with high TNM stage and poor grade showed the highest MC density. A higher PAR-2 immunoreactivity characterized tumours most infiltrated by MCs compared with samples with low MC density. Furthermore, PAR-2 overexpression was associated with advanced TNM stage, poor grade and lymphovascular invasion (LVI). A positive correlation existed between tryptase(+) MC density and PAR-2 expression. Cytoplasmic NHERF1 was higher in C than in NM and overexpressing tumours resulted associated with nodal and distant metastases, poor grade and LVI. PAR-2 correlated with cytoplasmic NHERF1 and the PAR-2(+)/cytoplasmic NHERF1(+) expression immunophenotype identified tumours associated with unfavourable prognosis and aggressive clinical parameters. Our data indicate that the high density of tryptase(+) MCs at invasive margins of tumours was associated with advanced stages of CRC and was strongly correlated with PAR-2 expression

Severity of oxidative stress and inflammatory activation in end-stage heart failure patients are unaltered after 1 month of left ventricular mechanical assistance

This study investigates the impact of early left ventricular (LV)-mechanical unloading on systemic oxidative stress and inflammation in terminal heart failure patients and their impact both on multi organ failure and on intensive care unit (ICU) stay. Circulating levels of urinary 15-isoprostane-F2t (8-epi-PGF2a) and pro-inflammatory markers [plasma interleukin (IL)-6, IL-8, and urinary neopterin, a monocyte activation index] were analyzed in 20 healthy subjects, 22 stable end-stage heart failure (ESHF) patients and in 23 LV assist device (LVAD) recipients at pre-implant and during first post-LVAD (PL) month. Multiorgan function was evaluated by total Sequential Organ Failure Assessment (tSOFA) score. In LVAD recipients the levels of oxidative-inflammatory markers and tSOFA score were higher compared to other groups. After device implantation 8-epi-PGF2a levels were unchanged, while IL-6, and IL-8 levels increased during first week, and at 1 month returned to pre-implant values, while neopterin levels increased progressively during LVAD support. The tSOFA score worsened at 1 PL-week with respect to pre-implant value, but improved at 1 PL-month. The tSOFA score related with IL-6 and IL-8 levels, while length of ICU stay related with pre-implant IL-6 levels. These data suggest that hemodynamic instability in terminal HF is associated to worsening of systemic inflammatory and oxidative milieu that do not improve in the early phase of hemodynamic recovery and LV-unloading by LVAD, affecting multi-organ function and length of ICU stay. This data stimulate to evaluate the impact of inflammatory signals on long-term outcome of mechanical circulatory support