Learning to rank from medical imaging data

Medical images can be used to predict a clinical score coding for the severity of a disease, a pain level or the complexity of a cognitive task. In all these cases, the predicted variable has a natural order. While a standard classifier discards this information, we would like to take it into account in order to improve prediction performance. A standard linear regression does model such information, however the linearity assumption is likely not be satisfied when predicting from pixel intensities in an image. In this paper we address these modeling challenges with a supervised learning procedure where the model aims to order or rank images. We use a linear model for its robustness in high dimension and its possible interpretation. We show on simulations and two fMRI datasets that this approach is able to predict the correct ordering on pairs of images, yielding higher prediction accuracy than standard regression and multiclass classification techniques

Oscillatory behavior of closed isotropic models in second order gravity theory

Homogeneous and isotropic models are studied in the Jordan frame of the second order gravity theory. The late time evolution of the models is analysed with the methods of the dynamical systems. The normal form of the dynamical system has periodic solutions for a large set of initial conditions. This implies that an initially expanding closed isotropic universe may exhibit oscillatory behaviour.Comment: 16 pages, 3 figures. With some minor improvements. To appear in General Relativity and Gravitatio

Matrix and Stimulus Sample Sizes in the Weighted MDS Model: Empirical Metric Recovery Functions

The only guidelines for sample size that exist in the multidimensional scaling (MDS) literature are a set of heuristic "rules-of-thumb" that have failed to live up to Young's (1970) goal of finding func tional relationships between sample size and metric recovery. This paper develops answers to two im portant sample-size questions in nonmetric weight ed MDS settings, both of which are extensions of work reported in MacCallum and Cornelius (1977): (1) are the sample size requirements for number of stimuli and number of matrices compensatory? and (2) what type of functional relationships exist between the number of matrices and metric recov ery ? The graphs developed to answer the second question illustrate how such functional relation ships can be defined empirically in a wide range of MDS and other complicated nonlinear models.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Dark Energy and Extending the Geodesic Equations of Motion: Its Construction and Experimental Constraints

With the discovery of Dark Energy, $\Lambda_{DE}$, there is now a universal length scale, $\ell_{DE}=c/(\Lambda_{DE} G)^{1/2}$, associated with the universe that allows for an extension of the geodesic equations of motion. In this paper, we will study a specific class of such extensions, and show that contrary to expectations, they are not automatically ruled out by either theoretical considerations or experimental constraints. In particular, we show that while these extensions affect the motion of massive particles, the motion of massless particles are not changed; such phenomena as gravitational lensing remain unchanged. We also show that these extensions do not violate the equivalence principal, and that because $\ell_{DE}=14010^{800}_{820}$ Mpc, a specific choice of this extension can be made so that effects of this extension are not be measurable either from terrestrial experiments, or through observations of the motion of solar system bodies. A lower bound for the only parameter used in this extension is set.Comment: 19 pages. This is the published version of the first half of arXiv:0711.3124v2 with corrections include

Thermal Decay of the Cosmological Constant into Black Holes

We show that the cosmological constant may be reduced by thermal production of membranes by the cosmological horizon, analogous to a particle ``going over the top of the potential barrier", rather than tunneling through it. The membranes are endowed with charge associated with the gauge invariance of an antisymmetric gauge potential. In this new process, the membrane collapses into a black hole, thus the net effect is to produce black holes out of the vacuum energy associated with the cosmological constant. We study here the corresponding Euclidean configurations ("thermalons"), and calculate the probability for the process in the leading semiclassical approximation.Comment: 14 pages, 6 figures. Minor correction

Bulk viscosity driving the acceleration of the Universe

The possibility that the present acceleration of the universe is driven by a kind of viscous fluid is exploited. At background level this model is similar to the generalized Chaplygin gas model (GCGM). But, at perturbative level, the viscous fluid exhibits interesting properties. In particular the oscillations in the power spectrum that plagues the GCGM are not present. Possible fundamental descriptions for this viscous dark energy are discussed.Comment: Latex file, 8 pages, 3 eps figure

Gravitational Coupling and Dynamical Reduction of The Cosmological Constant

We introduce a dynamical model to reduce a large cosmological constant to a sufficiently small value. The basic ingredient in this model is a distinction which has been made between the two unit systems used in cosmology and particle physics. We have used a conformal invariant gravitational model to define a particular conformal frame in terms of large scale properties of the universe. It is then argued that the contributions of mass scales in particle physics to the vacuum energy density should be considered in a different conformal frame. In this manner, a decaying mechanism is presented in which the conformal factor appears as a dynamical field and plays a key role to relax a large effective cosmological constant. Moreover, we argue that this model also provides a possible explanation for the coincidence problem.Comment: To appear in GR

Quintessence and variation of the fine structure constant in the CMBR

We study dependence of the CMB temperature anisotropy spectrum on the value of the fine structure constant $\alpha$ and the equation of state of the dark energy component of the total density of the universe. We find that bounds imposed on the variation of $\alpha$ from the analysis of currently available CMB data sets can be significantly relaxed if one also allows for a change in the equation of state.Comment: 5 pages, 3 figures. Several references added and a few minor typos corrected in the revised versio

Revised spherically symmetric solutions of R+ε/RR+\varepsilon/R gravity

We study spherically symmetric static empty space solutions in $R+\varepsilon/R$ model of $f(R)$ gravity. We show that the Schwarzschild metric is an exact solution of the resulted field equations and consequently there are general solutions which {are perturbed Schwarzschild metric and viable for solar system. Our results for large scale contains a logarithmic term with a coefficient producing a repulsive gravity force which is in agreement with the positive acceleration of the universe.Comment: 8 page