487 research outputs found

    Legal arguments for the inadmissibility of aplllying the nullity statute under public law against judicial acts

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    Indexación: Web of Science; Scielo.RESUMEN: La presente investigación constituye una respuesta desde el ámbito del Derecho Procesal a aquella parte de la doctrina que afirma la aplicación de la nulidad de derecho público a los actos jurisdiccionales. Lo que se pretende es exponer diversas razones que permitan demostrar que el estatuto de la nulidad de derecho público es jurídicamente improcedente aplicarlo contra los actos jurisdiccionales que adolecen de defectos o vicios de naturaleza procesal.ABSTRACT: This work is a response from the field of procedural law to part of the doctrine that supports the application of the public law nullity to judicial acts. The purpose of this research is to present a variety of reasons which show that the status of the invalidity of public law is legally inadmissible against judicial acts tainted by defects or vices of a procedural nature.http://ref.scielo.org/w8n4s

    Influence of methionine supplementation of growing diets enriched with lysine on feedlot performance and characteristics of digestion in Holstein steer calves.

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    ObjectiveTwo trials were conducted in order to examine the effects of level of supplemental methionine on productive performance, dietary energetic, plasma amino acid concentration, and digestive function.MethodsDietary treatments consisted of a steam-flaked corn-based diet containing urea as the only source of supplemental nitrogen supplemented with no supplemental amino acid (control), or control plus 1.01% lysine and 0.032%, 0.064%, 0.096%, or 0.128% methionine. In Trial 1, 150 Holstein steer calves (127±4.9 kg) were utilized to evaluate the influence of treatments on growth-performance, dietary energetic, plasma amino acid concentration during the first 112 days of growing period. During the initial 56-d period calves received the 5 experimental diets. During the subsequent 56-d period all calves were fed the control diet.ResultsDuring the initial 56-d period, methionine supplementation increased (linear effect, p<0.01) plasma methionine. In the presence of supplemental lysine, increases on level of methionine in diet did not affect average daily gain. However, increased gain efficiency (quadratic effect, p = 0.03) and estimated dietary net energy (NE; linear effect, p = 0.05). Estimated metabolizable methionine supply was closely associated (R2 = 0.95) with efficiency NE utilization for maintenance and gain. During the subsequent 56-d period, when all calves received the control diet (no amino acid supplementation), plasma amino acid concentrations and growth performance was not different among groups. However, the effects of methionine supplementation during the initial 56-period carried over, so that following a 56-d withdrawal of supplementation, the overall 112-d effects on gain efficiency (quadratic effect, p = 0.05) dietary NE (linear effect, p≤0.05) remained appreciable. In Trial 2, 5 cannulated Holstein steers were used to evaluate treatment effects on characteristics of digestion and amino acid supply to the small intestine. There were no treatment effects on flow of dietary and microbial N to the small intestine. Postruminal N digestion increased (p = 0.04) with increasing level of supplemental methionine. Methionine supplementation linearly increased (p<0.01) duodenal flow of methionine. Likewise, lysine supplementation increased an average of 4.6% (p = 0.04) duodenal flow of lysine. In steers that received non-supplemented diet, observed intestinal amino acid supply were in good agreement with expected.ConclusionWe conclude that addition of rumen-protected methionine and lysine to diets may enhance gain efficiency and dietary energetics of growing Holstein calves. Observed amino acid supply to the small intestine were in good agreement with expected, supportive of NRC (2000, Level 1)

    Diseño y construcción de prototipo de una máquina cortadora de papaya, melón y sandía para la elaboración de ensalada de frutas

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    El presente proyecto está orientado al diseño y construcción de un prototipo de máquina cortadora de frutas, utilizadas para la elaboración de ensaladas, y su propósito es optimizar el tiempo de corte y brindar seguridad al operador, busca también garantizar el cumplimiento de las necesidades y expectativas para el área de procesamiento y corte de alimentos en pequeños emprendimientos dedicados a brindar este servicio. Se ha recolectado información digital y física en distintos establecimientos alimenticios, utilizando el estudio comparativo se seleccionó la mejor alternativa para encontrar la solución al problema que pretende ayudar dicho proyecto.The present project is oriented to the design and construction of a prototype of a fruit cutting machine, used for the preparation of salads, and its purpose is to optimize the cutting time and provide safety to the operator, it also seeks to guarantee the fulfillment of the needs and expectations for the area of food processing and cutting in small businesses dedicated to providing this service. Digital and physical information has been collected in different food establishments, using the comparative study the best alternative was selected to find the solution to the problem that this project intends to help

    Estudio de CD 61, CD163 e ICAM-1 en la fisiopatología de aterotrombosis y efecto de la piel de manzana en la expresión de ICAM-1, en modelos animales

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    58 p.Las enfermedades cardiovasculares son la principal causa de muerte a nivel mundial, entre ellas las de tipo isquémicas son las más prevalentes, y en las cuales el desarrollo de placas ateroscleróticas es el proceso fisiopatológico central. El estudio de la aterosclerosis es fundamental para comprender como se inicia este proceso y los factores que influyen en su desarrollo. Distintas metodologías de laboratorio, como modelos animales de aterotrombosis e inmunohistoquímica, permiten reconocer células y moléculas que participan en el proceso ateromatoso las que van interactuando según la progresión de la lesión, entre ellas las plaquetas, monocito/macrófagos y moléculas de adhesión tal como ICAM-1. En este trabajo se realizó inmunohistoquímica para CD61, CD163 e ICAM-1 y se estudió su expresión en tres estadios del proceso ateromatoso, una etapa inicial representada por ratones CF-1 alimentados con dieta grasa, etapa avanzada obtenida con ratones ApoE- KO alimentados con dieta grasa y una etapa final de trombosis, realizada con FeCl3 en conejos neozelandeses. También se evaluó el efecto del suplemento de piel de manzana en una dieta rica en grasa sobre la expresión de ICAM-1, en ratones ApoE- KO. En los cortes de la etapa inicial se observó expresión endotelial para CD61, ICAM-1 y CD163, reflejado como una leve positividad para estos marcadores. En la etapa avanzada se observó gran positividad para el inmunomarcaje de las moléculas antes mencionadas a nivel endotelial como en el interior de la lesión ateromatosa. En la etapa de trombosis, los cortes mostraron positividad para los tres marcadores. Al estudiar, el efecto del suplemento de piel de manzana en la dieta grasa administrada a ratones ApoE- KO, se observó leve positividad para el inmunomarcaje de ICAM-1. Estos resultados demuestran la participación de las plaquetas en todo el proceso aterotrombótico, desde la disfunción endotelial hasta la etapa final de trombosis, en estrecha relación con monocito/macrófagos, esta interacción aumenta mientras avanza la enfermedad, principalmente en sitios donde existen núcleos lipídicos. Con respecto al efecto de la piel de manzana enla dieta ésta mostró una detención en la progresión de la enfermedad ateromatosa, observada como una disminución del tamaño de la placa, y una menor expresión de ICAM-1, comparado con los ratones alimentados solo con dieta grasa

    Efficiency of the osteopathic treatment for patients with whisplash injury

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    Este trabajo tiene como objetivo recoger información de las distintas técnicas de osteopatía manejadas en el tratamiento de pacientes con latigazo cervical y exponer la efectividad de las diferentes técnicas empleadas, las cuales tienen como objetivo, restablecer la función articular y liberar adherencias. Tras el análisis observamos que la biomecánica del síndrome del latigazo cervical, se corresponde con lesiones osteopáticas según las leyes de Fríete. El empleo de técnicas de manipulación cervical ha sido empleado en pacientes con síndromes de latigazo cervical; sin embargo, en el aspecto clínico analizado en nuestro estudio, contemplamos importante la movilización y manipulación de otras zonas afectadas.Terapia y Rehabilitació

    Posibilidades de los servicios ferroviarios nocturnos en la futura red europea de alta velocidad

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    La expansión de las líneas de Alta Velocidad que se está llevando a cabo en la práctica totalidad de los paises europeos permitirá disponer hacia 2020 de una verdadera red europea de ferrocarril de Alta Velocidad. Su entrada en servicio puede significar un relanzamiento de los trenes nocturnos internacionales, pues el uso de esta infraestructura por parte del material nocturno más tradicional y/o por un nuevo material de Alta Velocidad más novedoso, permitirá el establecimiento de conexiones nocturnas entre las poblaciones europeas más alejadas. Por tanto, la presente tesina tiene por objeto evaluar las posibilidades que tendrán los servicios nocturnos en este nuevo campo comprobando cómo reaccionará su cuota de mercado frente a los otros modos de transporte, fundamentalmente el avión

    Characterization of the Small RNA Transcriptome of the Marine Coccolithophorid, Emiliania huxleyi

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    Small RNAs (smRNAs) control a variety of cellular processes by silencing target genes at the transcriptional or post-transcription level. While extensively studied in plants, relatively little is known about smRNAs and their targets in marine phytoplankton, such as Emiliania huxleyi (E. huxleyi). Deep sequencing was performed of smRNAs extracted at different time points as E. huxleyi cells transition from logarithmic to stationary phase growth in batch culture. Computational analyses predicted 18 E. huxleyi specific miRNAs. The 18 miRNA candidates and their precursors vary in length (18-24 nt and 71-252 nt, respectively), genome copy number (3-1,459), and the number of genes targeted (2-107). Stem-loop real time reverse transcriptase (RT) PCR was used to validate miRNA expression which varied by nearly three orders of magnitude when growth slows and cells enter stationary phase. Stem-loop RT PCR was also used to examine the expression profiles of miRNA in calcifying and non-calcifying cultures, and a small subset was found to be differentially expressed when nutrients become limiting and calcification is enhanced. In addition to miRNAs, endogenous small RNAs such as ra-siRNAs, ta-siRNAs, nat-siRNAs, and piwiRNAs were predicted along with the machinery for the biogenesis and processing of si-RNAs. This study is the first genome-wide investigation smRNAs pathways in E. huxleyi. Results provide new insights into the importance of smRNAs in regulating aspects of physiological growth and adaptation in marine phytoplankton and further challenge the notion that smRNAs evolved with multicellularity, expanding our perspective of these ancient regulatory pathways

    Reorganización de las prácticas de compiladores para mejorar el aprendizaje de los estudiantes

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    La parte práctica de asignaturas como Compiladores o Procesadores de Lenguajes (las trataremos como la misma en el resto de la comunicación) suele ser bastante costosa, ya que requiere cierto grado de planificación y continuidad en el trabajo de los estudiantes y las herramientas utilizadas no tienen una conexión clara con los fundamentos teóricos. Nuestra propuesta estructura estas sesiones prácticas en tres tipos: las que se encargan de enlazar teoría y práctica, las que introducen a los estudiantes las herramientas de generación de compiladores y la final donde se desarrolla un compilador de cierta complejidad. Con este enfoque hemos mejorado el porcentaje de éxito en la parte práctica hasta un 86%.Peer Reviewe

    Analysis of the effect of COVID-19 on air pollution: Perspective of the Spanish case

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    [EN] The pandemic caused by coronavirus COVID-19 is having a worldwide impact that affects health and the economy and indirectly affects air pollution in cities. In Spain, the effect has evolved from being anecdotal in January 2020 to become the second country in Europe with the highest number of cases (614,000 cases by 17/09/2020), which has affected the health system and caused major mobility restrictions. In contrast, COVID-19 has affected air pollution and energy consumption in the country. This article analyzes the indirect effect produced by this pandemic on air pollution, referenced to various stages that occurred in Spain: first stage, without public awareness of COVID-19 impact (mid-January 2020); second is when Spanish Government alerted (late February 2020); and third, after the decree of alarm and mobility restriction of citizens by the government (March 2020) along with the various phases of the de-escalation. The indirect effect produced by this pandemic on air pollution in Spanish cities has been resulted in a decrement of 70% to 80% of average, taking into account dates after the decree of alarm and mobility restriction by the Spanish government (14/03/2020), compared to days prior to that date. Thus, the results of this analysis indicate a significant alteration in air pollutants; these alteration patterns have followed similar paths over different countries worldwide improving the air quality as discussed by Dutheil et al. (Environ Pollut (Barking, Essex: 1987) 263:114466, 2020).This work was supported by the European Union under the project Green Cities for Climate and Water Resilience, Sustainable Economic Growth, Healthy Citizens and Environments with reference 730283 and the framework of Condereff project (Ref. PGI05560Condereff) Construction & demolition waste management policies for improved resource efficiency.Cárcel-Carrasco, J.; Pascual Guillamón, M.; Langa Sanchis, J. (2021). 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Environ Pollut:115042. https://doi.org/10.1016/j.envpol.2020.115042Rojas NY, Ramírez O, Belalcázar LC, Méndez-Espinosa JF, Vargas JM, Pachón JE (2021) PM2. 5 emissions, concentrations and air quality index during the COVID-19 lockdown. Environ Pollut (Barking, Essex: 1987) 272:115973. https://doi.org/10.1016/j.envpol.2020.115973SEPAR. Sociedad Española de Neumología y Cirugía Torácica. Available online: https://www.separ.es/. Accessed on 06/07/2020Venter ZS, Aunan K, Chowdhury S, Lelieveld J (2020) COVID-19 lockdowns cause global air pollution declines. Proc Natl Acad Sci 117(32):18984–18990. https://doi.org/10.1073/pnas.2006853117Web1. Novel coronavirus spread tracking. Available online: https://graphics.reuters.com/CHINA-HEALTH-MAP/0100B59S39E/index.html. Accessed on 17/09/2020Web2. El comercio. Available online: URL:https://www.elcomercio.com/tendencias/aislamiento-covid19-reduccion-contaminacion-ambiente.html. Accessed on 20/03/2020Web3. 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