Rebel Recycling Program

The health of our planet or environmental protection is something that most people ignore until it becomes a bigger problem.https://digitalscholarship.unlv.edu/educ_fys_103/1000/thumbnail.jp

Mission Impracticable: The Impossibility of Commercial Impracticability

[Excerpt] “Residents of Chicago’s Streeterville neighborhood certainly cannot forget the recent financial crisis thanks to a gaping hole in their midst. That hole is to be the home of the Spire, the tallest building in the Northern Hemisphere, at 2,000 feet high with 1,194 residences ranging in price from $750,000 for a studio to$40 million for the penthouse. The developer, Shelbourne Development Group, Inc., began construction in 2007 using its own funds. It also obtained “starter” funds from Bank of America via a loan agreement that required Shelbourne to demonstrate proof of a construction loan by November 1, 2008. Although Shelbourne sold thirty percent of the building, it could not obtain construction financing due to the worsening global financial and credit crisis. Bank of America declared the loan in default and sued Shelbourne for the outstanding principal, interest, and fees. As part of its defense, Shelbourne argued that the court should excuse it (temporarily) from providing proof of a construction loan, due to the ‘unforeseeable and unprecedented economic downturn and recession, particularly in the real estate market.’

Level Up: Employing the Commerce Clause To Federalize the Sale of Goods

This Article argues that rather than wait until the defects become insurmountable, we should act now to address the defects in the law of sales and enact a federal sales act to supplant Article 2 using congressional power under the Commerce Clause. Part II details the defects of Article 2 that are in need of repair, which include creating inconsistent results across the states, failing to adapt to changing trends in our modern commercial environment, and utilizing a private drafting process that fails to balance the competing interests of businesses and consumers. Part II then demonstrates that the current uniform code model cannot correct those defects due to its biased, cumbersome, and consensus-oriented amendment process. Next, Part III proposes a federal sales act to replace Article 2 and explains why a federal sales act is a practical solution for the sale of goods. Although the concept of a federal sales act is not novel, the dramatic changes in our commercial environment over the past sixty years coupled with the decline of Article 2 make a federal sales act an appropriate route to achieving a uniform, simple, and predictable body of sales law. Finally, Part IV establishes the viability of a federal sales act under the Commerce Clause, demonstrating that such an act is precisely the type of legislation intended by the clause despite recent Supreme Court rulings. Moreover, a federal sales act is consistent with the principles of federalism under which the Framers founded the United States of America

Two Too Many: Third Party Beneficiaries of Warranties Under the Uniform Commercial Code

(Excerpt) This Article surveys and analyzes the current version of section 2-318 and suggests improvements so that section 2-318 produces more uniform and equitable results that better facilitate interstate commerce in today’s complex commercial environment. Part I discusses the historical genesis of section 2- 318, specifically the common law concept of privity and its progression to the current version of section 2-318. Part II expounds upon certain issues with section 2-318 as currently drafted, which include lack of uniformity and lack of remedy for a valid breach of warranty claim. Part III establishes how the courts have begun eroding the concept of privity in spite of the language of section 2-318, thus eliminating the need for alternatives. Part IV proposes improvements to section 2-318 in accordance with current case law and public policy aimed at protecting consumers. Finally, Part V demonstrates that the states would adopt the proposed provision given today’s consumer-centric society

Expression levels and role of the de novo DNA methyltransferases in rhabdomyosarcoma

Aberrant DNA methylation has been frequently observed in human cancers, including rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, representing approximately 5% of malignant solid tumour in the paediatric population. However, the specific mechanisms and targets are still poorly understood. We showed the up-regulation of DNA methyltransferase (DNMT) family members in 14 RMS primary tumour biopsies and 4 RMS cell lines in comparison to normal skeletal muscle (NSM). Our study focused on DNMT3B gene, which exhibited particularly high levels in RMS samples, in order to establish its individual role in this malignancy. RNA interference-mediated DNMT3B knock-down decreased cell proliferation, by arresting cell cycle at G1 phase, as demonstrated by the reduced expression of Cyclin B1, Cyclin D1 and Cyclin E2, and by the concomitant up-regulation of the p21 and p27 checkpoint regulators. DNMT3B depleted cells also showed a decreased migratory capacity and clonogenic potential in comparison to mocked controls. Interestingly, DNMT3B silencing was able to reactivate the skeletal muscle differentiation program in embryonal RMS (ERMS) cells, as confirmed by the acquisition of a myogenic-like phenotype and by the increased expression of the myogenic markers MYOD1, Myogenin and MyHC. Inhibition of MEK/ERK signalling by U0126 resulted in a reduction of DNMT3B protein, leading to cell cycle arrest and myogenic terminal differentiation, this supporting the methyltransferase as a down-stream molecule of the MEK/ERK oncogenic pathway. Moreover, we showed that DNMT3B is a target of specific miR-29 family members in RMS cells and that the restoration of miRNA expression levels, by miRNA mimic transfection, lead to decreased cell proliferation and migration and to G1 cell cycle arrest. Finally, DNMT3B silencing radiosensitizes ERMS cells by altering DNA damage response signalling. Taken together, our data shed further light on RMS development, underlying a pivotal role of DNMT3B gene in myogenic program. Epigenetic therapy, by targeting the DNA methylation machinery, may represent a novel and promising strategy against RMS tumour able to ameliorate traditional therapies in order to improve the survival rate for patients with this soft tissue sarcoma

Resilience en el Valle: Remembering Bazan y Longoria and Reckoning with a Century of State Sponsored Violence

Poster includes list of events and sponsors.https://scholarworks.utrgv.edu/ehh2018/1008/thumbnail.jp

NEW SPECIES OF STAPHYLINIDAE (COL.) FROM NEW GUINEA AND MISOOL

abstract not availabl

Level Up: Employing the Commerce Clause To Federalize the Sale of Goods

This Article argues that rather than wait until the defects become insurmountable, we should act now to address the defects in the law of sales and enact a federal sales act to supplant Article 2 using congressional power under the Commerce Clause. Part II details the defects of Article 2 that are in need of repair, which include creating inconsistent results across the states, failing to adapt to changing trends in our modern commercial environment, and utilizing a private drafting process that fails to balance the competing interests of businesses and consumers. Part II then demonstrates that the current uniform code model cannot correct those defects due to its biased, cumbersome, and consensus-oriented amendment process. Next, Part III proposes a federal sales act to replace Article 2 and explains why a federal sales act is a practical solution for the sale of goods. Although the concept of a federal sales act is not novel, the dramatic changes in our commercial environment over the past sixty years coupled with the decline of Article 2 make a federal sales act an appropriate route to achieving a uniform, simple, and predictable body of sales law. Finally, Part IV establishes the viability of a federal sales act under the Commerce Clause, demonstrating that such an act is precisely the type of legislation intended by the clause despite recent Supreme Court rulings. Moreover, a federal sales act is consistent with the principles of federalism under which the Framers founded the United States of America