112 research outputs found

    C9orf72 expansions disrupt ATM-mediated DNA repair

    Get PDF

    Safety Monitoring for Large Language Models: A Case Study of Offshore Wind Maintenance

    Get PDF
    It has been forecasted that a quarter of the world's energy usage will be supplied from Offshore Wind (OSW) by 2050 (Smith 2023). Given that up to one third of Levelised Cost of Energy (LCOE) arises from Operations and Maintenance (O&M), the motive for cost reduction is enormous. In typical OSW farms hundreds of alarms occur within a single day, making manual O&M planning without automated systems costly and difficult. Increased pressure to ensure safety and high reliability in progressively harsher environments motivates the exploration of Artificial Intelligence (AI) and Machine Learning (ML) systems as aids to the task. We recently introduced a specialised conversational agent trained to interpret alarm sequences from Supervisory Control and Data Acquisition (SCADA) and recommend comprehensible repair actions (Walker et al. 2023). Building on recent advancements on Large Language Models (LLMs), we expand on this earlier work, fine tuning LLAMA (Touvron 2018), using available maintenance records from EDF Energy. An issue presented by LLMs is the risk of responses containing unsafe actions, or irrelevant hallucinated procedures. This paper proposes a novel framework for safety monitoring of OSW, combining previous work with additional safety layers. Generated responses of this agent are being filtered to prevent raw responses endangering personnel and the environment. The algorithm represents such responses in embedding space to quantify dissimilarity to pre-defined unsafe concepts using the Empirical Cumulative Distribution Function (ECDF). A second layer identifies hallucination in responses by exploiting probability distributions to analyse against stochastically generated sentences. Combining these layers, the approach finetunes individual safety thresholds based on categorised concepts, providing a unique safety filter. The proposed framework has potential to utilise the O&M planning for OSW farms using state-of-the-art LLMs as well as equipping them with safety monitoring that can increase technology acceptance within the industry

    A Deep Learning Framework for Wind Turbine Repair Action Prediction Using Alarm Sequences and Long Short Term Memory Algorithms

    Get PDF
    With an increasing emphasis on driving down the costs of Operations and Maintenance (O&\&M) in the Offshore Wind (OSW) sector, comes the requirement to explore new methodology and applications of Deep Learning (DL) to the domain. Condition-based monitoring (CBM) has been at the forefront of recent research developing alarm-based systems and data-driven decision making. This paper provides a brief insight into the research being conducted in this area, with a specific focus on alarm sequence modelling and the associated challenges faced in its implementation. The paper proposes a novel idea to predict a set of relevant repair actions from an input sequence of alarm sequences, comparing Long Short-term Memory (LSTM) and Bidirectional LSTM (biLSTM) models. Achieving training accuracy results of up to 80.23%\%, and test accuracy results of up to 76.01%\% with biLSTM gives a strong indication to the potential benefits of the proposed approach that can be furthered in future research. The paper introduces a framework that integrates the proposed approach into O&\&M procedures and discusses the potential benefits which include the reduction of a confusing plethora of alarms, as well as unnecessary vessel transfers to the turbines for fault diagnosis and correction

    A massive quiescent galaxy at redshift 4.658

    Get PDF
    A. C. Carnall thanks the Leverhulme Trust for their support via a Leverhulme Early Career Fellowship. R. J. McLure, J. S. Dunlop, D. J. McLeod, V. Wild, R. Begley, C. T. Donnan and M. L. Hamadouche acknowledge the support of the Science and Technology Facilities Council. F. Cullen acknowledges support from a UKRI Frontier Research Guarantee Grant (grant reference EP/X021025/1). A. Cimatti acknowledges support from the grant PRIN MIUR 2017 - 20173ML3WW 001.The extremely rapid assembly of the earliest galaxies during the first billion years of cosmic history is a major challenge for our understanding of galaxy formation physics (1; 2; 3; 4; 5). The advent of JWST has exacerbated this issue by confirming the existence of galaxies in significant numbers as early as the first few hundred million years (6; 7; 8). Perhaps even more surprisingly, in some galaxies, this initial highly efficient star formation rapidly shuts down, or quenches, giving rise to massive quiescent galaxies as little as 1.5 billion years after the Big Bang (9; 10), however, due to their faintness and red colour, it has proven extremely challenging to learn about these extreme quiescent galaxies, or to confirm whether any exist at earlier times. Here we report the spectroscopic confirmation of a massive quiescent galaxy, GS-9209, at redshift, z = 4.658, just 1.25 billion years after the Big Bang, using JWST NIRSpec. From these data we infer a stellar mass of M∗ = 3.8 ± 0.2 × 1010 M⊙, which formed over a ≃ 200 Myr period before this galaxy quenched its star formation activity at z=6.5+0.2−0.5, when the Universe was ≃ 800 million years old. This galaxy is both a likely descendent of the highest-redshift submillimetre galaxies and quasars, and a likely progenitor for the dense, ancient cores of the most massive local galaxies.PostprintPeer reviewe

    A cognitive perspective on equivalent effect: using eye tracking to measure equivalence in source text and target text cognitive effects on readers

    Get PDF
    Eye-tracking methods have long been used to explore cognitive processing in reading, but the recent burgeoning of such methods in the field of translation studies has focused almost entirely on the translation process or audiovisual translation, neglecting the effects of the translation product itself. This paper presents a proof-of-concept study using eye tracking to compare fixation data between native readers of a French literary source text and native readers of its English translation at specific, corresponding points in the texts. The preliminary data are consistent with previous findings on the relationship between the features of the fixated word and fixation durations. These findings are also consistent with stylistic analyses and indicate that this method can be used to compare the levels of cognitive effort between two readership groups in order to investigate whether their experience is similar – whether an ‘equivalent effect’ has been achieved – thus contributing to the ongoing discourse surrounding equivalence in translation studies

    Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

    Get PDF
    A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

    Evidence gaps and biodiversity threats facing the marine environment of the United Kingdom’s Overseas Territories

    Get PDF
    Understanding the evidence base and identifying threats to the marine environment is critical to ensure cost-effective management and to identify priorities for future research. The United Kingdom (UK) government is responsible for approximately 2% of the world’s oceans, most of which belongs to its 14 Overseas Territories (UKOTs). Containing biodiversity of global significance, and far in excess of the UK mainland’s domestic species, there has recently been a strong desire from many of the UKOTs, the UK Government, and NGOs to improve marine management in these places. Implementing evidence-based marine policy is, however, challenged by the disparate nature of scientific research in the UKOTs and knowledge gaps about the threats they face. Here, we address these issues by systematically searching for scientific literature which has examined UKOT marine biodiversity and by exploring publicly available spatial threat data. We find that UKOT marine biodiversity has received consistent, but largely low, levels of scientific interest, and there is considerable geographical and subject bias in research effort. Of particular concern is the lack of research focus on management or threats to biodiversity. The extent and intensity of threats vary amongst and within the UKOTs but unsurprisingly, climate change associated threats affect them all and direct human stressors are more prevalent in those with higher human populations. To meet global goals for effective conservation and management, there is an urgent need for additional and continued investment in research and management in the Overseas Territories, particularly those that have been of lesser focus
    corecore