267 research outputs found
Angular, spectral, and time distributions of highest energy protons and associated secondary gamma-rays and neutrinos propagating through extragalactic magnetic and radiation fields
The angular, spectral and temporal features of the highest energy protons and
accompanying them secondary neutrinos and synchrotron gamma-rays propagating
through the intergalactic magnetic and radiation fields are studied using the
analytical solutions of the Boltzmann transport equation obtained in the limit
of the small-angle and continuous-energy-loss approximation.Comment: 21 pages, 13 figure
Spectral Energy Distributions of Gamma Ray Bursts Energized by External Shocks
Sari, Piran, and Narayan have derived analytic formulas to model the spectra
from gamma-ray burst blast waves that are energized by sweeping up material
from the surrounding medium. We extend these expressions to apply to general
radiative regimes and to include the effects of synchrotron self-absorption.
Electron energy losses due to the synchrotron self-Compton process are also
treated in a very approximate way. The calculated spectra are compared with
detailed numerical simulation results. We find that the spectral and temporal
breaks from the detailed numerical simulation are much smoother than the
analytic formulas imply, and that the discrepancies between the analytic and
numerical results are greatest near the breaks and endpoints of the synchrotron
spectra. The expressions are most accurate (within a factor of ~ 3) in the
optical/X-ray regime during the afterglow phase, and are more accurate when
epsilon_e, the fraction of swept-up particle energy that is transferred to the
electrons, is <~ 0.1. The analytic results provide at best order-of-magnitude
accuracy in the self-absorbed radio/infrared regime, and give poor fits to the
self-Compton spectra due to complications from Klein-Nishina effects and
photon-photon opacity.Comment: 16 pages, 7 figures, ApJ, in press, 537, July 1, 2000. Minor changes
in response to referee report, corrected figure
Depth of the vadose zone controls aquifer biogeochemical conditions and extent of anthropogenic nitrogen removal
© The Author(s), 2017. This is the author's version of the work and is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Water Research 123 (2017): 794-801, doi:10.1016/j.watres.2017.06.048.We investigated biogeochemical conditions and watershed features controlling the extent of nitrate removal through microbial dinitrogen (N2) production within the surficial glacial aquifer located on the north and south shores of Long Island, NY, USA. The extent of N2 production differs within portions of the aquifer, with greatest N2 production observed at the south shore of Long Island where the vadose zone is thinnest, while limited N2 production occurred under the thick vadose zones on the north shore. In areas with a shallow water table and thin vadose zone, low oxygen concentrations and sufficient DOC concentrations are conducive to N2 production. Results support the hypothesis that in aquifers without a significant supply of sediment-bound reducing potential, vadose zone thickness exerts an important control of the extent of N2 production. Since quantification of excess N2 relies on knowledge of equilibrium N2 concentration at recharge, calculated based on temperature at recharge, we further identify several features, such as land use and cover, seasonality of recharge, and climate change that should be considered to refine estimation of recharge temperature, its deviation from mean annual air temperature, and resulting deviation from expected equilibrium gas concentrations.Project supported by the Polish-U.S. Fulbright Commission, the USGS Coastal and Marine Geology Program, the National Fish and Wildlife Foundation, and the USGS/National Park Service Water-Quality Assessment and Monitoring program.2019-06-1
Haplotype of prostaglandin synthase 2/cyclooxygenase 2 is involved in the susceptibility to inflammatory bowel disease
AIM: Prostaglandin G/H synthase 2 (PTGS2 or COX2) is one of the key factors in the cellular response to inflammation. PTGS2 is expressed in the affected intestinal segments of patients with inflammatory bowel diseases (IBD). In IBD patients, non-steroidal anti-inflammatory drugs, which have been shown to reduce both the production and activity of PTGS2, may activate IBD and aggravate the symptoms. We aimed at examining genetic variants of PTGS2 that may be risk factors for IBD. METHODS: We genotyped 291 individuals diagnosed with IBD and 367 controls from the Dutch population for the five most frequent polymorphisms of the PTGS2 gene. Clinical data were collected on all patients. DNA was extracted via normal laboratory methods. Genotyping was carried out using multiplex PCR followed by the Invader Assay and the 5 exonuclease assay (TaqMan). New polymorphism screening was performed by pre-screening with denaturing high-performance liquid chromatography, followed by fluorescent sequencing. RESULTS: Allele 5209G was weakly associated with Crohn's disease (odds ratio [OR] 1.63, 95% confidence interval [CI] 1.03-2.57), and allele 8473T with ulcerative colitis (OR 1.50, 95%CI 1.00-2.27). The haplotype including both alleles showed a strong association with IBD (OR 13.15, 95%CI 3.17-116.15). This haplotype, while rare (-0.3%) in the general population, is found more frequently in patients (3.5%). CONCLUSION: Our data suggest that this haplotype of PTGS2 contributes to the susceptibility of IBD
Is pore water oxygen content decoupled from productivity on the California Margin? Trace element results from Ocean Drilling Program Hole 1017E, San Lucia slope, California
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95250/1/palo1223.pd
Radio galaxies and magnetic fields in A514
A514 contains six extended and polarized radio sources located at various
projected distances from the cluster center. Here we present a detailed study
of these six radio sources in total intensity and polarization using the Very
Large Array at 3.6 and 6 cm. Since the radio sources sample different lines of
sight across the cluster, an analysis of the Faraday Rotation Measures (RMs)
provides information on the strength and the structure of the cluster magnetic
field. These sources show a decreasing Faraday Rotation Measure with increasing
distance from the cluster center. We estimate the strength of the magnetic
field to be ~3-7 uG in the cluster center. From the RM structure across the
stronger and more extended sources we estimate the coherence length of the
magnetic field to be about 9 kpc at the cluster center.Comment: 16 pages, 18 ps figures accepted by A&
Multiwavelength observations of Mkn 501 during the 1997 high state
During the observation period 1997, the nearby Blazar Mkn 501 showed
extremely strong emission and high variability. We examine multiwavelength
aspects of this event using radio, optical, soft and hard X-ray and TeV data.
We concentrate on the medium-timescale variability of the broadband spectra,
averaged over weekly intervals.
We confirm the previously found correlation between soft and hard X-ray
emission and the emission at TeV energies, while the source shows only minor
variability at radio and optical wavelengths. The non-linear correlation
between hard X-ray and TeV fluxes is consistent with a simple analytic estimate
based on an SSC model in which Klein-Nishina effects are important for the
highest-energy electrons in the jet, and flux variations are caused by
variations of the electron density and/or the spectral index of the electron
injection spectrum.
The time-averaged spectra are fitted with a Synchrotron Self-Compton (SSC)
dominated leptonic jet model, using the full Klein-Nishina cross section and
following the self-consistent evolution of relativistic particles along the
jet, accounting for gamma-gamma absorption and pair production within the
source as well as due to the intergalactic infrared background radiation. The
contribution from external inverse-Compton scattering is tightly constrained by
the low maximum EGRET flux and found to be negligible at TeV energies. We find
that high levels of the X-ray and TeV fluxes can be explained by a hardening of
the energy spectra of electrons injected at the base of the jet, in remarkable
contrast to the trend found for gamma-ray flares of the flat-spectrum radio
quasar PKS 0528+134.Comment: accepted for publication in ApJ, 31 pages, 11 figure
Submarine groundwater discharge to a small estuary estimated from radon and salinity measurements and a box model
Author Posting. © 2005 Author(s). This work is licensed under a Creative Commons License. The definitive version was published Biogeosciences 2 (2005): 141-157, doi:10.5194/bg-2-141-2005.Submarine groundwater discharge was quantified by a variety of methods for a 4-day period during the early summer of 2004, in Salt Pond, adjacent to Nauset Marsh, on Cape Cod, USA. Discharge estimates based on radon and salinity took advantage of the presence of the narrow channel connecting Salt Pond to Nauset Marsh, which allowed constructing whole-pond mass balances as water flowed in and out due to tidal fluctuations. The data suggest that less than one quarter of the discharge in the vicinity of Salt Pond happened within the pond itself, while three quarters or more of the discharge occurred immediately seaward of the pond, either in the channel or in adjacent regions of Nauset Marsh. Much of this discharge, which maintains high radon activities and low salinity, is carried into the pond during each incoming tide. A box model was used as an aid to understand both the rates and the locations of discharge in the vicinity of Salt Pond. The model achieves a reasonable fit to both the salinity and radon data assuming submarine groundwater discharge is fresh and that most of it occurs either in the channel or in adjacent regions of Nauset Marsh. Salinity and radon data, together with seepage meter results, do not rule out discharge of saline groundwater, but suggest either that the saline discharge is at most comparable in volume to the fresh discharge or that it is depleted in radon. The estimated rate of fresh groundwater discharge in the vicinity of Salt Pond is 3000-7000 m3 d-1. This groundwater flux estimated from the radon and salinity data is comparable to a value of 3200-4500 m3 d-1 predicted by a recent hydrologic model (Masterson, 2004; Colman and Masterson, 2004), although the model predicts this rate of discharge to the pond whereas our data suggest most of the groundwater bypasses the pond prior to discharge. Additional work is needed to determine if the measured rate of discharge is representative of the long-term average, and to better constrain the rate of groundwater discharge seaward of Salt Pond.Financial support was provided by the US Geological Survey
and by National Science Foundation grant #OCE-0346933 to MAC
Combined carriership of TLR9-1237C and CD14-260T alleles enhances the risk of developing chronic relapsing pouchitis
AIM: To investigate the single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition and the susceptibility to pouchitis or pouchitis severity. METHODS: Analyses of CD14 -260C>T, CARD15/NOD2 3020insC, Toll-like receptor (TLR)4 +896A>G, TLR9 -1237T>C, TLR9+2848G>A, and IRAKM + 22148G>A SNPs were performed in 157 ileal-pouch anal anastomosis (IPAA) patients (79 patients who did not develop pouchitis, 43 infrequent pouchitis patients, 35 chronic relapsing pouchitis patients) and 224 Italian Caucasian healthy controls. RESULTS: No significant differences were found in SNP frequencies between controls and IPAA patients. However, a significant difference in carriership frequency of the TLR9-1237C allele was found between the infrequent pouchitis and chronic relapsing pouchitis groups [P = 0.028, oddos ratio (OR) = 3.2, 95%CI = 1.2-8.6]. This allele uniquely represented a 4-locus TLR9 haplotype comprising both studied TLR9 SNPs in Caucasians. Carrier trait analysis revealed an enhanced combined carriership of the alleles TLR9 -1237C and CD14 -260T in the chronic relapsing pouchitis and infrequent pouchitis group (P = 0.018, OR = 4.1, 95%CI = 1.4 -12.3). CONCLUSION: There is no evidence that the SNPs predispose to the need for IPAA surgery. The significant increase of the combined carriership of the CD14 -260T and TLR9 -1237C alleles in the chronic relapsing pouchitis group suggests that these markers identify a subgroup of IPAA patients with a risk of developing chronic or refractory pouchitis
Absorption of 10 Gev--1 Tev Gamma Rays by Radiation from Broad-Line Region in 3C 279
In this paper, we study the photon-photon pair production optical depth for
10 GeV--1 TeV gamma rays from 3C 279 due to the diffuse radiation of broad-line
region (BLR). Assuming a power-law spectrum of for the
photon intensity of very high energy (VHE) gamma rays, and
are inferred by the integrated photon fluxes measured by MAGIC
and HESS. Based on this power-law spectrum, the pre-absorbed spectra are
inferred by correcting the photon-photon absorption on the diffuse photons of
the BLR (internal absorption) and the extragalactic background light (external
absorption). Position of gamma-ray emitting region determines
the relative contributions of this two diffuse radiation to the total
absorption for 10 GeV--1 TeV gamma rays. The internal absorption could make
spectral shape of gamma rays more complex than only corrected for the external
absorption, and could lead to the formation of arbitrary softening and
hardening gamma-ray spectra. It should be necessary for the internal absorption
to be considered in studying 10 GeV--1 TeV gamma rays from powerful blazars.
The energies of annihilated gamma-ray photons due to the internal absorption
are likely to be mainly reradiated around GeV. Our results indicate that
may be between the inner and outer radii of the BLR for 3C
279. This implies for powerful blazars that might be neither
inside the BLR cavity nor outside the BLR, but be within the BLR shell.
Observations of , MAGIC, HESS, and VERITAS in the near future could
give more constraints on the position of the gamma-ray emitting region relative
to the BLR.Comment: 29 pages, 7 figures, Received: 4 June 2008, Accepted in ApJ: 18 Jul
200
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