Orthodontic and surgical rehabilitation children with Treacher Collins syndrome

Rezumat. Sindromul Treacher Collins (TCS) este o tulburare autozomal dominantă rară a dezvoltării cranio-faciale. Este o malformaţie congenitală a primului şi celui de-al doilea arc branial care poate afecta dimensiunea şi forma urechilor, pleoapelor, oaselor pomeţilor şi maxilarelor. Tratamentul cu success planificarea operate cu Dolphin Soft efectuind LeFort I si BSSO si Genioplastie. Examinind 2 parametri cefalometrici importanti ca SNB, Co-Go-Me.Summary. Treacher Collins syndrome (TCS) is a rare autosomal dominant disorder of craniofacial development. It is a congenital malformation of first and second branchial arch which may affect the size and shape of the ears, eyelids, cheek bones, and jaws. Exam firs and after surgery with Dolphin Soft with LeFort I and BSSO and Genioplasty. In this article was described TCS with exam SNB, Co-Go-Me

Rolul resurselor informaționale electronice în asigurarea procesului de instruire. Cazul BȘM

Introduction. In contemporary society, the primary function of university libraries remains to provide information and documentation of training processes and research. In order to fulfill its mission, the Scientific Medical Library is obliged to respond to the challenges of the electronic environment by integrating in the new informational and communication context. Objective of the study. To identify the role of electronic information resources in ensuring the training process. Material and Methods. In the research process were applied quantitative and qualitative methods: the questionnaire, the analysis and synthesis of the obtained results, the analysis of the modalities and sources of acquisition of electronic resources, the study of advanced experiences. Results. The results of the study showed that electronic information resources are an important segment of the collection of the Scientific Medical Library of the Nicolae Testemitanu University and are considered effective tools for information and documentation. Their use in the process of informing the beneficiaries contributes to the satisfaction of the various information requirements for study and research. Conclusions. The information resources development policy of the Scientific Medical Library should focus mainly on electronic documents, due to the many facilities they offer. The library should intensify the development of the electronic segment of medical and pharmaceutical information resources and further create the necessary conditions for using of these types of documents.Introducere. În societatea contemporană, funcția primordială a bibliotecilor universitare rămâne a fi asigurarea infodocumentară a proceselor de instruire și cercetare. Pentru a-și îndeplini misiunea, BȘM este obligată să răspundă provocărilor mediului electronic integrându-se în noul context informațional și de comunicare. Scopul lucrării: Identificarea rolului resurselor informaționale electronice în asigurarea procesului de instruire. Material și Metode. În procesul de cercetare au fost aplicate metode cantitative, dar și calitative: chestionarul, analiza și sinteza rezultatelor obținute, analiza modalităților și surselor de achiziție a resurselor electronice, studierea experiențelor avansate. Rezultate. Rezultatele studiului au demonstrat că resursele informaționale electronice constituie un segment important al fondului Bibliotecii Științifice Medicale USMF „Nicolae Testemițanu” și sunt considerate instrumente eficiente de informare și documentare. Utilizarea lor în procesul de servire informațională contribuie la satisfacerea diverselor cerințe de informare pentru studiu și cercetare. Concluzii. Politica de dezvoltare a resurselor informaționale a Bibliotecii Științifice Medicale trebuie să pună accent preponderent pe documentele electronice, datorită numeroaselor facilități pe care le oferă acestea. Biblioteca trebuie să intensifice dezvoltarea segmentului electronic al resurselor informaționale de profil medical și farmaceutic și să creeze în continuare condiții necesare pentru utilizarea acestor genuri de documente

THE ROLE OF ELECTRONIC INFORMATION RESOURCES IN ENSURING THE TRAINING PROCESS. SCIENTIFIC MEDICAL LIBRARY CASE

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroducere. În societatea contemporană, funcția primordială a bibliotecilor universitare rămâne a fi asigurarea infodocumentară a proceselor de instruire și cercetare. Pentru a-și îndeplini misiunea, BȘM este obligată să răspundă provocărilor mediului electronic integrându-se în noul context informațional și de comunicare. Scopul lucrării: Identificarea rolului resurselor informaționale electronice în asigurarea procesului de instruire. Material și Metode. În procesul de cercetare au fost aplicate metode cantitative, dar și calitative: chestionarul, analiza și sinteza rezultatelor obținute, analiza modalităților și surselor de achiziție a resurselor electronice, studierea experiențelor avansate. Rezultate. Rezultatele studiului au demonstrat că resursele informaționale electronice constituie un segment important al fondului Bibliotecii Științifice Medicale USMF „Nicolae Testemițanu” și sunt considerate instrumente eficiente de informare și documentare. Utilizarea lor în procesul de servire informațională contribuie la satisfacerea diverselor cerințe de informare pentru studiu și cercetare. Concluzii. Politica de dezvoltare a resurselor informaționale a Bibliotecii Științifice Medicale trebuie să pună accent preponderent pe documentele electronice, datorită numeroaselor facilități pe care le oferă acestea. Biblioteca trebuie să intensifice dezvoltarea segmentului electronic al resurselor informaționale de profil medical și farmaceutic și să creeze în continuare condiții necesare pentru utilizarea acestor genuri de documente.Introduction. In contemporary society, the primary function of university libraries remains to provide information and documentation of training processes and research. In order to fulfill its mission, the Scientific Medical Library is obliged to respond to the challenges of the electronic environment by integrating in the new informational and communication context. Objective of the study. To identify the role of electronic information resources in ensuring the training process. Material and Methods. In the research process were applied quantitative and qualitative methods: the questionnaire, the analysis and synthesis of the obtained results, the analysis of the modalities and sources of acquisition of electronic resources, the study of advanced experiences. Results. The results of the study showed that electronic information resources are an important segment of the collection of the Scientific Medical Library of the Nicolae Testemitanu University and are considered effective tools for information and documentation. Their use in the process of informing the beneficiaries contributes to the satisfaction of the various information requirements for study and research. Conclusions. The information resources development policy of the Scientific Medical Library should focus mainly on electronic documents, due to the many facilities they offer. The library should intensify the development of the electronic segment of medical and pharmaceutical information resources and further create the necessary conditions for using of these types of documents

Sodium, potassium and iodine intake, in a national adult population sample of the Republic of Moldova

In the Republic of Moldova, more than half of all deaths due to noncommunicable diseases (NCDs) are caused by cardiovascular disease (CVD). Excess salt (sodium) and inadequate potassium intakes are associated with high CVD. Moreover, salt iodisation is the preferred policy to prevent iodine deficiency and associated disorders. However, there is no survey that has directly measured sodium, potassium and iodine consumption in adults in the Republic of Moldova. A national random sample of adults attended a screening including demographic, anthropometric and physical measurements. Sodium, potassium and iodine intakes were assessed by 24 h urinary sodium (UNa), potassium (UK) and iodine (UI) excretions. Knowledge, attidues and behaviours were collected by questionnaire. Eight-hundred and fifty-eight participants (326 men and 532 women, 18–69 years) were included in the analysis (response rate 66%). Mean age was 48.5 years (SD 13.8). Mean UNa was 172.7 (79.3) mmoL/day, equivalent to 10.8 g of salt/day and potassium excretion 72.7 (31.5) mmoL/day, equivalent to 3.26 g/day. Only 11.3% met the World Health Organization (WHO) recommended salt targets of 5 g/day and 39% met potassium targets (>90 mmoL/day). Whilst 81.7% declared limiting their consumption of processed food and over 70% not adding salt at the table, only 8.8% looked at sodium content of food, 31% still added salt when cooking and less than 1% took other measures to control salt consumption. Measures of awareness were significantly more common in urban compared to rural areas. Mean urinary iodine was 225 (SD: 152; median 196) mcg/24 h, with no difference between sexes. According to WHO criteria, 41.0% had adequate iodine intake. Iodine content of salt table was 21.0 (SD: 18.6) mg/kg, lower in rural than urban areas (16.7, SD = 18.6 vs. 28.1, SD = 16.5 mg/kg, p < 0.001). In most cases participants were not using iodised salt as their main source of salt, more so in rural areas. In the Republic of Moldova, salt consumption is unequivocally high, potassium consumption is lower than recommended, both in men and in women, whilst iodine intake is still inadequate in one in three people, although severe iodine deficiency is rare. Salt consumed is often not iodised. View Full-Tex

Histological and immunohistochemical evaluation of mandibular bone tissue regeneration

The purpose of the study was to perform an immunohistochemical and histological evaluation of samples taken from different bone regeneration procedures in atrophic human mandible. 30 patients (15 men and 15 women, age range of 35-60 years), non-smokers, with good general and oral health were recruited in this study and divided into three groups. The first group included patients who were treated with blood Concentration Growth Factors (bCGF), the second group included patients who were treated with a mixture of bCGF and autologous bone, while the third group of patients was treated with bCGF and tricalcium phosphate/hydroxyapatite (TCP-HA). Six months after the regenerative procedures, all patients undergone implant surgery, and a bone biopsy was carried out in the site of implant insertion. Each sample was histologically and immunohistochemically examined. Histological evaluation showed a complete bone formation for group II, partial ossification for group I, and moderate ossification for group III. Immunohistochemical analysis demonstrated a statistically significant difference between the three groups, and the best clinical result was obtained with a mixture of bCGF and autologous bone

Intoleranţa ortostatică. Conceptul modern, clasificarea, manifestările clinice şi algoritmul de tratament

Intoleranţa ortostatică este o cauză semnifi cativă de invalidizare a persoanelor de vârstă reproductivă. Tahicardia ortostatică este deseori cea mai evidentă dereglare hemodinamică la subiecţii cu intoleranţă ortostatică. Prezentarea clinică poate culmina cu incapacitatea de a menţine normotensiunea, cu presincopa sau sincopa succesivă. Acest articol prezintă sumarul ultimilor informaţii privind înţelegerea acestei patologii, mecanismele fi ziopatologice şi abordările terapeutice existente la moment

Aspecte ale patternului vegetativ la nou-născuţi

Studiul realizat de noi se referă la cercetarea specifi cului patternului vegetativ (PV) la nou-născuţi, în perioada primelor 30 de zile, în evoluţia dezvoltării organismului. PV a fost evaluat prin parametrii ciclului de respiraţie și cei ai ritmicităţii respiratorii și cardiace. Studiul a relevat patternuri specifi ce anumitor etape de dezvoltare, între care în perioada neonatală se remarcă: (a) ziua a 4-a de viaţă ca importantă în constituirea funcţiilor ventilatorii – ciclului și ritmului respirator; (b) perioada neonatală tardivă impune un specifi c propriu al PV; (c) pare importantă poziţionarea nou-născutului în cadrul specifi cului PV și (d) sunt semnifi cative corelaţiile dintre parametrii ritmicităţii respiratorii și celei cardiace

Clinical-epidemiological characteristics of adults hospitalized with Covid–19 in the Republic of Moldova

Introduction: The COVID-19 pandemic has a major negative impact on health and socio-economic well-being. Understanding the characteristics of COVID-19 disease and identifying the wide range of factors affecting health and quality of life can be the key to providing viable solutions to improve the management of patients and their physical and psycho-emotional rehabilitation. The purpose of the present study was to evaluate the influence of SARS CoV-2 infection on the health status of adults hospitalized with the diagnosis of COVID-19 in the Republic of Moldova. Material and methods: The presented study is a retrospective, cohort, consisting of a sample of 7441 patients randomly selected, aged 18 y.o. and older, hospitalized in 10 public medical institutions in Chisinau, Moldova. Diagnosis of COVID-19 was confirmed by detection of CoV-2 SARS RNA. The data in the patients’ medical records were processed and stored according to the unified, pre-established form, prepared in accordance with the requirements of the software „Electronic Patient Record COVID-19”. The severity of COVID-19 disease was assessed using two principles: (1) according to the criteria of the National Clinical Protocol PCN-371; (2) according to the 7-point graduated scale developed by the WHO Special Committee (V.3.0, 3 March 2020) in randomized multicenter clinical trials. Result: Only 30.07% patients mentioned the presence of a close contact with a COVID-19 positive person. The average age of the patients in the study was 52.83 years. Mild form was diagnosed in 5.00% of patients, medium - 66.15%, severe –20.67%, critical-8.18%. The main complaints of patients were fever, fatigue or physical asthenia, cough, and headache. More than 1/4 of those hospitalized have severe or critical forms of COVID-19; more than 1/3 - require oxygen therapy, and every 6-th patient needs non-invasive high-flow oxygen ventilation or mechanical ventilation. Old age, male sex, chronic comorbidities increase statistically significantly the probability of patients having an unfavorable prognosis in COVID-19. 7.93% of patients died, according to the age group: every 2-nd patient over 90 years, every 3-rd over 80 years, every 5-th over 70 years, and every 9-th over 60 years died. Conclusions: (1) The uncertainty of the source of infection lead to delay specific prophylactic public health measures; (2) In COVID-19, in a hospital-type medical management, the emphasis should be placed mainly on patients over the age of 50; (3) There is no specific clinical manifestation in COVID-19, that would allow to distinguish the disease from other pathologies; (4) Age over 60 y.o., male sex, and chronic cardiovascular diseases, diabetes mellitus, chronic kidneys diseases and malignant tumors unfavorable influence the evolution of COVID-19; (5) Antibiotic administration remains at a high level in hospitalized patients and is often unjustified and unnecessary

Anemia aplastică la copil: protocol clinic naţional PCN-110

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, IMșiCAcest protocol a fost elaborat de grupul de lucru al Ministerului Sănătăţii al Republicii Moldova (MS RM), constituit din specialiştii Cursului de Pediatrie a Universităţii de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” în colaborare cu specialiştii din secţia hematologie a IMSP Institutul Mamei şi Copilului. Protocolul naţional este elaborat în conformitate cu Ghidurile internaţionale actuale privind AA la copii şi va servi drept bază pentru elaborarea Protocoalelor clinice instituţionale. La recomandarea MS pentru monitorizarea Protocoalelor clinice instituţionale pot fi folosite formulare suplimentare, care nu sunt incluse în Protocolul clinic naţiona

Anemiile hemolitice la copil: protocol clinic naţional PCN-109

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, IMșiCAcest protocol a fost elaborat de grupul de lucru al Ministerului Sănătăţii al Republicii Moldova (MS RM), constituit din specialiştii Cursului de pediatrie a Universităţii de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” în colaborare cu specialiştii din secţia hematologie a IMSP Institutul Mamei şi Copilului. Protocolul naţional este elaborat în conformitate cu Ghidurile internaţionale actuale privind AH la copiişi va servi drept bază pentru elaborarea Protocoalelor clinice instituţionale. La recomandarea MS pentru monitorizarea Protocoalelor clinice instituţionale pot fi folosite formulare suplimentare, care nu sunt incluse în Protocolul clinic naţional