7 research outputs found
Human leukocyte antigens as genetic markers in Greek patients with sporadic pancreatic cancer
No full textPurpose: In this study we investigated the relationship between specific
HLA antigens and sporadic pancreatic cancer in Greek population.
Methods: The allele frequencies of serologically and molecular defined
class I and II HLA antigens were studied in 60 unrelated patients with
pancreatic cancer histologically confirmed. The results obtained for HLA
frequencies were compared with those of 105 healthy control subjects
(control group).
Results: Increased frequencies of HLA-A30 (16.7 vs. 3.8%; P < 0.01; OR
= 5.05), A31 (9.5 vs. 1.9%; P < 0.05; OR = 5.72), B18 (31.7 vs.
14.3%,- P < 0.05; OR = 2.78) and Cw7 (53.3 vs. 21.9%; P < 0.01; OR =
4.07) were observed in patients with pancreatic cancer in comparison to
the control subjects.
Conclusions: This study demonstrates the association between specific
HLA antigens and pancreatic cancer development in whites and suggests a
genetic susceptibility factor for the disease
Potential Probiotic Lactic Acid Bacteria of Human Origin Induce Antiproliferation of Colon Cancer Cells via Synergic Actions in Adhesion to Cancer Cells and Short-Chain Fatty Acid Bioproduction
No full text
Effect of Dietary Fibers on Cecal Microbiota and Intestinal Tumorigenesis in Azoxymethane Treated A/J Min/+ Mice
No full text
