2,065 research outputs found
Business Environment, User Involvement, and Information System Success:A Case Study
User involvement has always been considered an important contributor to the success of information systems, despite inconclusive evidences to support such claims. None of the studies on user involvement have paid attention to environmental context. This paper reports on a system that demonstrates how the external environment actually affects user involvement and system success. It also provide some insights for future research on user involvement
Contractive De-noising Auto-encoder
Auto-encoder is a special kind of neural network based on reconstruction.
De-noising auto-encoder (DAE) is an improved auto-encoder which is robust to
the input by corrupting the original data first and then reconstructing the
original input by minimizing the reconstruction error function. And contractive
auto-encoder (CAE) is another kind of improved auto-encoder to learn robust
feature by introducing the Frobenius norm of the Jacobean matrix of the learned
feature with respect to the original input. In this paper, we combine
de-noising auto-encoder and contractive auto- encoder, and propose another
improved auto-encoder, contractive de-noising auto- encoder (CDAE), which is
robust to both the original input and the learned feature. We stack CDAE to
extract more abstract features and apply SVM for classification. The experiment
result on benchmark dataset MNIST shows that our proposed CDAE performed better
than both DAE and CAE, proving the effective of our method.Comment: Figures edite
Assessment of the applicability of failure frequency models for dense phase carbon dioxide pipelines
In Carbon Capture, Usage and Storage (CCUS) schemes, Carbon Dioxide (CO2) is captured from large scale industrial emitters and transported to geological sites for storage. The most efficient method for the transportation of CO2 is via pipeline in the dense phase. CO2 is a hazardous substance which, in the unlikely event of an accidental release, could cause people harm. To correspond with United Kingdom (UK) safety legislation, the design and construction of proposed CO2 pipelines requires compliance with recognised pipeline codes. The UK code PD-8010-1 defines the separation distance between a hazardous pipeline and a nearby population as the minimum distance to occupied buildings using a substance factor. The value of the substance factor should be supported by the results of a Quantitative Risk Assessment (QRA) approach to ensure the safe design, construction and operation of a dense phase CO2 pipeline. Failure frequency models are a major part of this QRA approach and the focus of this paper is a review of existing oil and gas pipeline third-party external interference failure frequency models to assess whether they could be applied to dense phase CO2 pipelines. It was found that the high design pressure requirement for a dense phase CO2 pipeline typically necessitates the use of high wall thickness linepipe in pipeline construction; and that the wall thickness of typical dense phase CO2 pipelines is beyond the known range of applicability for the pipeline failure equations used within existing failure frequency models. Furthermore, even though third party external interference failure frequency is not sensitive to the product that a pipeline transports, there is however a limitation to the application of existing UK fault databases with to onshore CO2 pipelines as there are currently no dense phase CO2 pipelines operating in the UK. Further work needs to be conducted to confirm the most appropriate approach for calculating failure frequency for dense phase CO2 pipelines, and it is recommended that a new failure frequency model suitable for dense phase CO2 pipelines is developed that can be readily updated to the latest version of the fault database
A Pair of Disjoint 3-GDDs of type g^t u^1
Pairwise disjoint 3-GDDs can be used to construct some optimal
constant-weight codes. We study the existence of a pair of disjoint 3-GDDs of
type and establish that its necessary conditions are also sufficient.Comment: Designs, Codes and Cryptography (to appear
The Virial Equation of State of Low-Density Neutron Matter
We present a model-independent description of low-density neutron matter
based on the virial expansion. The virial equation of state provides a
benchmark for all nuclear equations of state at densities and temperatures
where the interparticle separation is large compared to the thermal wavelength.
We calculate the second virial coefficient directly from the nucleon-nucleon
scattering phase shifts. Our results for the pressure, energy, entropy and the
free energy correctly include the physics of the large neutron-neutron
scattering length. We find that, as in the universal regime, thermodynamic
properties of neutron matter scale over a wide range of temperatures, but with
a significantly reduced interaction coefficient compared to the unitary limit.Comment: 7 pages, 6 figures, minor revisions, to appear in Phys. Lett.
Dynamic transition in driven vortices across the peak effect in superconductors
We study the zero-temperature dynamic transition from the disordered flow to
an ordered flow state in driven vortices in type-II superconductors. The
transition current is marked by a sharp kink in the
characteristic with a concomitant large increase in the defect concentration.
On increasing magnetic field , the follows the behaviour of the
critical current . Specifically, in the peak effect regime
increases rapidly along with . We also discuss the effect of varying
disorder strength on .Comment: 4 pages, 4 figure
Flowability and physical properties of wheat-unripe plantain (Musa paradisiaca) composite flour
This study investigated the flowability and physical properties of composite flour made
from wheat flour mixed with unripe plantain flour at different ratios (70:30, 80:20 and
90:10, respectively and 100% wheat flour as control). Unripe plantain flour was chosen
because it has high iron content which can resolve diet issues encountered by anaemic and
celiac patients due to low iron and high protein (gluten) content in consumption of wheat
bread. Physical properties of the composite flour were determined: bulk density, tapped
density, angle of repose, and flowability. The proximate analysis such as ash, lipid, fibre,
carbohydrate, protein, moisture content of the mixed flour was determined as well as iron
content. The density of the composite flour was increased as the unripe plantain flour in
the mix ratio increased, suggesting that unripe plantain flour was denser than the
substituted wheat flour. The flow indexes of the composite flours show excellent freeflowing behaviour as the Carr Index (CI) and Hausner Ratio (HR) were within the range of
the powder that exhibited free-flowing properties. The use of plantain flour increased the
proximate composition of the composite flour except for protein content which is
advantageous to the celiac patients who do not need much of the bread protein (gluten).
The iron content was increased with the increase of unripe plantain flour in the mix ratio,
favouring anaemic patients who require more iron. Incorporation of higher amount of
unripe plantain flour reduced the swelling power of the dough which affected the bread
making process
Defining the molecular pathology of pancreatic body and tail adenocarcinom
Background:
Pancreatic ductal adenocarcinoma (PDAC) remains a dismal disease, with very little improvement in survival over the past 50 years. Recent large-scale genomic studies have improved understanding of the genomic and transcriptomic landscape of the disease, yet very little is known about molecular heterogeneity according to tumour location in the pancreas; body and tail PDACs especially tend to have a significantly worse prognosis. The aim was to investigate the molecular differences between PDAC of the head and those of the body and tail of the pancreas.
Methods:
Detailed correlative analysis of clinicopathological variables, including tumour location, genomic and transcriptomic data, was performed using the Australian Pancreatic Cancer Genome Initiative (APGI) cohort, part of the International Cancer Genome Consortium study.
Results:
Clinicopathological data were available for 518 patients recruited to the APGI, of whom 421 underwent genomic analyses; 179 of these patients underwent whole-genome and 96 RNA sequencing. Patients with tumours of the body and tail had significantly worse survival than those with pancreatic head tumours (12·1 versus 22·0 months; P = 0·001). Location in the body and tail was associated with the squamous subtype of PDAC. Body and tail PDACs enriched for gene programmes involved in tumour invasion and epithelial-to-mesenchymal transition, as well as features of poor antitumour immune response. Whether this is due to a molecular predisposition from the outset, or reflects a later time point on the tumour molecular clock, requires further investigation using well designed prospective studies in pancreatic cancer.
Conclusion:
PDACs of the body and tail demonstrate aggressive tumour biology that may explain worse clinical outcomes
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