Fuzzy rule based multiwavelet ECG signal denoising

Since different multiwavelets, pre- and post-filters have different impulse responses and frequency responses, different multiwavelets, pre- and post-filters should be selected and applied at different noise levels for signal denoising if signals are corrupted by additive white Gaussian noises. In this paper, some fuzzy rules are formulated for integrating different multiwavelets, pre- and post-filters together so that expert knowledge on employing different multiwavelets, pre- and post-filters at different noise levels on denoising performances is exploited. When an ECG signal is received, the noise level is first estimated. Then, based on the estimated noise level and our proposed fuzzy rules, different multiwavelets, pre- and post-filters are integrated together. A hard thresholding is applied on the multiwavelet coefficients. According to extensive numerical computer simulations, our proposed fuzzy rule based multiwavelet denoising algorithm outperforms traditional multiwavelet denoising algorithms by 30%

Data mining on existing game selling platforms 現成的電玩遊戲售賣平台內的數據探索

This project involves building a website to let people access game information as consolidated from a range of popular game selling platforms. This information includes not only comparisons among the prices offered on various game selling platforms, but also other information such as the publishers and system requirements... 本項目旨在發展一個單一網站平台，藉此整合及發佈多個廣受歡迎的遊戲銷售資訊，方便玩家進行比較。這些資訊不僅包括同一款遊 戲在不同銷售平台上的格價參考，也會列出發行商、系統要求等訊 息。 Award: Silver 奬項: 銀

A Novel Percutaneous Screw Fixation of Postero-lateral Tibial Plateau Fracture using Posterior Cruciate Ligament Reconstruction Femoral Template: Technical Note 使用後交叉韌帶重建股骨模板重建後外側脛骨平台骨折的一種新的經皮螺釘固定法:技術說明

AbstractPercutaneous fixation method has been applied in Schatzker type III joint depressed-type lateral tibial plateau fracture. We report a 76-year-old man suffering from a small joint depressed-type posterolateral tibial plateau fracture with surgical reduction and fixation with a novel guidance of posterior cruciate ligament (PCL) reconstruction femoral template under X-ray and arthroscopic assistance. The concept of sequential tunnel drilling in ligament reconstruction has been applied in bone impaction tunnel creation beneath the articular step with the PCL jig. Avoidance of multiple bone guide pin drilling and accurate guide pin insertion and hence screw fixation was also achieved by use of the PCL template. As illustrated, we believe that the PCL jig is a good armamentarium and adjunct equipment to achieve a more precise minimally invasive operation in special anatomical positions such as the postero-lateral tibial plateau under careful surgical planning

OMMA enables population-scale analysis of complex genomic features and phylogenomic relationships from nanochannel-based optical maps.

BackgroundOptical mapping is an emerging technology that complements sequencing-based methods in genome analysis. It is widely used in improving genome assemblies and detecting structural variations by providing information over much longer (up to 1 Mb) reads. Current standards in optical mapping analysis involve assembling optical maps into contigs and aligning them to a reference, which is limited to pairwise comparison and becomes bias-prone when analyzing multiple samples.FindingsWe present a new method, OMMA, that extends optical mapping to the study of complex genomic features by simultaneously interrogating optical maps across many samples in a reference-independent manner. OMMA captures and characterizes complex genomic features, e.g., multiple haplotypes, copy number variations, and subtelomeric structures when applied to 154 human samples across the 26 populations sequenced in the 1000 Genomes Project. For small genomes such as pathogenic bacteria, OMMA accurately reconstructs the phylogenomic relationships and identifies functional elements across 21 Acinetobacter baumannii strains.ConclusionsWith the increasing data throughput of optical mapping system, the use of this technology in comparative genome analysis across many samples will become feasible. OMMA is a timely solution that can address such computational need. The OMMA software is available at https://github.com/TF-Chan-Lab/OMTools

Fuzzy multiwavelet denoising on an ECG signal

Since different multiwavelets, pre- and post-filters have different impulse and frequency responses characteristics, different multiwavelets, pre- and post-filters should be selected, integrated and applied at different noise levels if a signal is corrupted by an additive white Gaussian noise (AWGN). In this letter, some fuzzy rules on selecting and integrating different multiwavelets, pre- and post-filters together are proposed. These fuzzy rules are setup based on the training results of the denoising performances of applying different multiwavelets, pre- and post-filters at different noise levels. When a new electrocardiogram (ECG) signal is applied, the appropriate multiwavelets, pre- and post-filters are selected and integrated based on fuzzy rules and the noise level of the signal. A hard thresholding is applied on the multiwavelet coefficients. According to an extensive simulation, we found that our proposed fuzzy rule-based multiwavelet denoising algorithm achieves 30% improvement compared to the traditional multiwavelet denoising algorithms

Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke

Background: Patients with myocardial infarction (MI) are at risk of the development of atrial fibrillation (AF) and ischemic stroke. We sought to evaluate the prognostic performance of the CHADS2 and CHA2DS2-VASc scores in predicting new AF and/or ischemic stroke in post-ST segment elevation MI (STEMI) patients. Six hundred and seven consecutive post-STEMI patients with no previously documented AF were studied.Methods and Results: After a follow-up of 63 months (3,184 patient-years), 83 (13.7%) patients developed new AF (2.8% per year). Patients with a high CHADS2 and/or CHA2DS2-VASc score were more likely to develop new AF. The annual incidence of new AF was 1.18%, 2.10%, 4.52%, and 7.03% in patients with CHADS2 of 0, 1, 2, and ≥ 3; and 0.39%, 1.72%, 1.83%, and 5.83% in patients with a CHA2DS2-VASc score of 1, 2, 3 and ≥ 4. The CHA2DS2-VASc score (C-statistic = 0.676) was superior to the CHADS2 (C-statistic = 0.632) for discriminating new AF. Ischemic stroke occurred in 29 patients (0.9% per year), the incidence increasing in line with the CHADS2 (0.41%, 1.02%, 1.11%, and 1.95% with score of 0, 1, 2, and ≥ 3) and CHA2DS2-VASc scores (0.39%, 0.49%, 1.02%, and 1.48% with score of 1, 2, 3 and ≥ 4). The C-statistic of the CHA2DS2-VASc score as a predictor of ischemic stroke was 0.601, superior to that of CHADS2 score (0.573). CHADS2 and CHA2DS2-VASc scores can identify post-STEMI patients at high risk of AF and stroke.Conclusions: The CHADS2 and CHA2DS2-VASc scores can identify post-STEMI patients at high risk of AF and ischemic stroke. This enables close surveillance and prompt anticoagulation for stroke prevention

Thermal comfort and energy performance of public rental housing under typical and near-extreme weather conditions in Hong Kong

© 2017 Elsevier B.V. Building performance evaluation is crucial for sustainable urban developments. In high-density cities, occupants suffer from poor living conditions due to building overheating, especially during increasingly frequent near-extreme summer conditions caused by climate change. To represent this situation, the summer reference year weather data was employed for building simulations using DesignBuilder. This study aims to evaluate the thermal comfort and energy consumption of four typical public rental housing (PRH) building types in Hong Kong. For free-running flats, results show generally higher air temperatures in the oldest PRH type (Slab) with a compact linear building form and the most sensitive response to outdoor temperature changes for another older PRH type (Trident) with a Y-shaped design, possibly owing to its high wall conductivity. Occupants in all building types experience a ???10% increase in the proportion of discomfort hours when compared to results for typical summer conditions, but overheating is the most severe in Slab type PRH. Following an initial assessment of the cooling energy usage, a simple sensitivity test was conducted to explore the potential energy savings by various passive design strategies, including shading and reducing the exposed cooled space. A cross-shaped building form also appears to be more energy efficient. These findings, complemented by further parametric analyses, may prove useful when designing buildings for climate change

Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions.

We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing community transmission. By fitting a stochastic model to data on 1512 cases, including these clusters, we show that the etiological agent of SARS is moderately transmissible. Excluding SSEs, we estimate that 2.7 secondary infections were generated per case on average at the start of the epidemic, with a substantial contribution from hospital transmission. Transmission rates fell during the epidemic, primarily as a result of reductions in population contact rates and improved hospital infection control, but also because of more rapid hospital attendance by symptomatic individuals. As a result, the epidemic is now in decline, although continued vigilance is necessary for this to be maintained. Restrictions on longer range population movement are shown to be a potentially useful additional control measure in some contexts. We estimate that most currently infected persons are now hospitalized, which highlights the importance of control of nosocomial transmission