Rimas infantiles: Producci?n textual a partir de la lectura del contexto escolar

95 p. Recurso Electr?nicoLa investigaci?n Rimas Infantiles, se enmarca dentro del macro-proyecto Redescubrir la Escuela del grupo de investigaci?n Argonautas y hace parte de la versi?n ?Cartografiar el territorio para comprender la escuela? del semillero de investigaci?n Lenguaje y Territorio Escolar. Rimas Infantiles parte de los siguientes conceptos: El territorio espacio f?sico, social y cultural que encierra a toda una poblaci?n y la hace diferente a otras; la cartograf?a social asumida como la representaci?n de la realidad a partir de mapas; el lenguaje se refiere al medio para expresar experiencias mediante s?mbolos, se?ales o sonidos; pr?cticas pedag?gicas para evidenciar los saberes y proyectar el conocimiento. El trabajo Rimas infantiles, parte de la siguiente pregunta: ?C?mo fomentar h?bitos de lectura y escritura para la creaci?n de rimas infantiles a partir del contexto escolar, con los estudiantes del grado segundo de b?sica primaria? La investigaci?n facilita vincular la cartograf?a con la formaci?n del Licenciado en Lengua Castellana para la comprensi?n de la realidad para fortalecer procesos pedag?gicos pertinentes. El territorio de observaci?n es la escuela Puerto Montero de la Instituci?n educativa Nuevo Horizonte del municipio de Girardot con los estudiantes del grado segundo. Colombia, A?o 2015-2016.The nursery rhymes Project is based into macro project ?Rediscovering the School by the Research Group Argonauts and it is part of the versi?n ?To map the territory for understanding the school? by the Research seed language and school territory?. Nursery rhymesbegins from the following concepts: the territory as a physical, social and cultural space which encloses a population and it makes different from others; The social mapping assumed like the representation of the reality from maps; the language refers the mean for expressing by mean of symbols, signs or sounds; pedagogycal practices for evidencing and to Project the knowledge. The nursery rhymes Project, begins from the next question: How to promote Reading and Writing habitsfor the creation of nursery rhymes base don the school context, with students from the second grade in primary school? The Research facilitate to link the mapping with teaching and learning process in Castillian Language for understanding the reality to improve the pedagogical processes. The place which the Project is based is the educative institution named NUEVO HORIZONTE in the city of Girardot with the students from second grade. Colombia, year 2015-2016. Keywords: social mapping school territory, pedagogical practices, rhymes

Non-Gaussian geostatistical modeling using (skew) t processes

We propose a new model for regression and dependence analysis when addressing spatial data with possibly heavy tails and an asymmetric marginal distribution. We first propose a stationary process with t marginals obtained through scale mixing of a Gaussian process with an inverse square root process with Gamma marginals. We then generalize this construction by considering a skew-Gaussian process, thus obtaining a process with skew-t marginal distributions. For the proposed (skew) t process, we study the second-order and geometrical properties and in the t case, we provide analytic expressions for the bivariate distribution. In an extensive simulation study, we investigate the use of the weighted pairwise likelihood as a method of estimation for the t process. Moreover we compare the performance of the optimal linear predictor of the t process versus the optimal Gaussian predictor. Finally, the effectiveness of our methodology is illustrated by analyzing a georeferenced dataset on maximum temperatures in Australia

Detection and dynamics of circulating tumor cells in patients with high-risk prostate cancer treated with radiotherapy and hormones: a prospective phase II study

BACKGROUND: Circulating tumor cells (CTCs) are an established prognostic marker in castration-resistant prostate cancer but have received little attention in localized high-risk disease. We studied the detection rate of CTCs in patients with high-risk prostate cancer before and after androgen deprivation therapy and radiotherapy to assess its value as a prognostic and monitoring marker. PATIENTS AND METHODS: We performed a prospective analysis of CTCs in the peripheral blood of 65 treatment-naive patients with high-risk prostate cancer. EpCAM-positive CTCs were enumerated using the CELLSEARCH system at 4 timepoints. A cut off of 0 vs >/= 1 CTC/7.5 ml blood was defined as a threshold for negative versus positive CTCs status. RESULTS: CTCs were detected in 5/65 patients (7.5%) at diagnosis, 8/62 (12.9%) following neoadjuvant androgen deprivation and 11/59 (18.6%) at the end of radiotherapy, with a median CTC count/7.5 ml of 1 (range, 1-136). Only 1 patient presented a positive CTC result 9 months after radiotherapy. Positive CTC status (at any timepoint) was not significantly associated with any clinical or pathologic factors. However, when we analyzed variations in CTC patterns following treatment, we observed a significant association between conversion of CTCs and stages T3 (P = 0.044) and N1 (P = 0.002). Detection of CTCs was not significantly associated with overall survival (P > 0.40). CONCLUSIONS: Our study showed a low detection rate for CTCs in patients with locally advanced high-risk prostate cancer. The finding of a de novo positive CTC count after androgen deprivation therapy is probably due to a passive mechanism associated with the destruction of the tumor. Further studies with larger samples and based on more accurate detection of CTCs are needed to determine the potential prognostic and therapeutic value of this approach in non-metastatic prostate cancer. TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT01800058

Galician multidisciplinary consensus about the use of lipid-lowering drugs

Se desarrolla un consenso multidisciplinar sobre el uso de hipolipemiantes, pues las cifras de consumo de hipolipemiantes han aumentado considerablemente en los ultimos años, Las últimas guías publicadas han levantado bastante polémica y se considera necesario la realización de este consenso e identificar los niveles de riesgo de los pacientes, para tratar las dislipemias y normalizar el uso de hipolipemientes. Se realiza una mención especial al tratamiento de la dislipemia en la enfermedad renal crónica

Do Land Use Policies Follow Road Construction?

We study whether local land use policies are modified in response to enhanced demand for building generated by a new highway, and examine the extent to which this effect of land use regulations affects building activity. We focus on the case of Spain during the last housing boom (1995-2007). We assembled a new database with information about new highway segments and the modification of the land zoning status in nearby municipalities. The empirical strategy compares the variation in the amount of developable land before-after the construction of the highway in treated municipalities and in control municipalities with similar pre-treatment traits. Our results show that, following the construction of a highway, municipalities converted a huge amount of land from rural to urban uses. We also show that new highways have an impact on building activity

The velocity reversal hypothesis and the implications to the sustainability of pool-riffle bed morphology /by Diego Caama{tilde}no.

Pool-riffle sequences are known to be critical habitat for several species of fish and benthic organisms. The morphological complexity of pool-riffle channels provides conditions for spawning, refugia and feeding.;Pool riffle sequences normally occur in low gradient gravel-bed rivers, and it has been observed that these features are sometimes very resilient despite significant disturbance in the stream or major changes in sediment delivery from the watershed, but in other cases a relatively minor disturbance results in significant loss of pool habitat.;Mechanisms responsible for pool-riffle maintenance are unclear and despite contributions from many researchers, no universal explanation has been developed. The most popular hypothesis for pool-riffle sustainability is the occurrence of velocity reversal, i.e. at low flows the maximum velocities in the channel occur across the riffle, but at higher less frequent flows the area of maximum velocity migrates to the pool. Reversal of velocity may cause corresponding reversal of shear stress and transport capacity that scours sediment previously deposited in the pool, with the larger clasts being deposited on the downstream riffle due to relatively lower competence, thereby providing a mechanism for maintenance of the pool-riffle morphology.;The velocity reversal hypothesis for pool-riffle channels was first proposed by Keller (1971) based on observations made by Gilbert (1914) and raised considerable interest and debate among scientists in the intervening years. A diverse range of opinions about whether this process exists and, if it does, the conditions under which it can be expected to occur had been discussed in the literature (Chapter 1: Pool-Riffle Sustainability and Velocity Reversal).;In this study, conditions potentially responsible for velocity reversal are critically assessed using published data from field studies and supplemented by additional field data collected by the author. An analytical solution for the physical conditions required for velocity reversal is developed. Although this approach uses a one-dimensional approximation to analyze the flow field through pool-riffle sequences, the simple analytical equation correctly predicts whether velocity reversal occurs in all cases cited in the literature, and quantifies the physical characteristics of the channel morphology necessary for reversal to occur. Results show that reversal depends critically on the ratio of riffle-to-pool width, residual pool depth (difference between pool and riffle elevations) and on the depth of flow over the riffle (Chapter 2: A Unifying Criterion for the Velocity Reversal Hypothesis in Gravel-Bed Rivers).;In addition, three-dimensional numerical modeling was performed to study the effects of different discharge and pool aggradation scenarios on channel hydraulics and the implications for velocity reversal. Two consecutive pool-riffle sequences at the Red River Wildlife Management Area in northern Idaho were chosen as a study site for this investigation. The model allows characterization of the flow structure, and identification of jet formation and dissipation zones, as well as the development of local turbulence features (i.e. vertical and horizontal eddies). The analysis demonstrated a significant influence of the residual pool depth on the flow structure. With pool aggradation and reduced residual depth causing a shift in the orientation of the jet and reduction in the influence of vertical eddies and the size and intensity of horizontal eddies. Based on these detailed observations and simulations of the flow structure through pools, a conceptual model is proposed to explain the sustainability of self-formed pool-riffle sequences in gravel-bed rivers due to jet formation and dissipation zones (Chapter 3: The Flow Structure in Pool-Riffle Sequences).;Further insight to the velocity reversal process and the associated bed shear stress and transport capacity variations were investigated at the site using the three-dimensional model results. Local depth-average, surface and near-bed velocities were evaluated and reversal assessed for all modeled scenarios. Results show that cross-section average velocities, near- bed velocities, shear stress and flux reversal do not all occur at the same discharge. Furthermore, the results corroborate the conclusion of the simple one-dimensional analysis (Chapter 2) and also show the importance of the location of the concentrated jet flow (Chapter 4: A Mechanism for Sustainability of Self-formed Pool-riffle Sequences).;Finally, recommendations for further work investigating the mechanisms of jet dissipation are suggested. The author believes that clarification on this matter will help to explain the spacing between pools and riffles (Chapter 5: Recommendations for Further Work).Thesis (Ph. D., Civil Engineering)--University of Idaho, December 2008