309 research outputs found
Theory of Cylindrical Tubules and Helical Ribbons of Chiral Lipid Membranes
We present a general theory for the equilibrium structure of cylindrical
tubules and helical ribbons of chiral lipid membranes. This theory is based on
a continuum elastic free energy that permits variations in the direction of
molecular tilt and in the curvature of the membrane. The theory shows that the
formation of tubules and helical ribbons is driven by the chirality of the
membrane. Tubules have a first-order transition from a uniform state to a
helically modulated state, with periodic stripes in the tilt direction and
ripples in the curvature. Helical ribbons can be stable structures, or they can
be unstable intermediate states in the formation of tubules.Comment: 43 pages, including 12 postscript figures, uses REVTeX 3.0 and
epsf.st
Rigid Chiral Membranes
Statistical ensembles of flexible two-dimensional fluid membranes arise
naturally in the description of many physical systems. Typically one encounters
such systems in a regime of low tension but high stiffness against bending,
which is just the opposite of the regime described by the Polyakov string. We
study a class of couplings between membrane shape and in-plane order which
break 3-space parity invariance. Remarkably there is only {\it one} such
allowed coupling (up to boundary terms); this term will be present for any
lipid bilayer composed of tilted chiral molecules. We calculate the
renormalization-group behavior of this relevant coupling in a simplified model
and show how thermal fluctuations effectively reduce it in the infrared.Comment: 11 pages, UPR-518T (This replaced version has fonts not used
removed.
Search for CP Violation in the decays D+ -> K_S pi+ and D+ -> K_S K+
A high statistics sample of photo-produced charm from the FOCUS(E831)
experiment at Fermilab has been used to search for direct CP violation in the
decays D+->K_S pi+ and D+ -> K_S K+. We have measured the following asymmetry
parameters relative to D+->K-pi+pi+: A_CP(K_S pi+) = (-1.6 +/- 1.5 +/- 0.9)%,
A_CP(K_S K+) = (+6.9 +/- 6.0 +/- 1.5)% and A_CP(K_S K+) = (+7.1 +/- 6.1 +/-
1.2)% relative to D+->K_S pi+. The first errors quoted are statistical and the
second are systematic. We also measure the relative branching ratios:
\Gamma(D+->\bar{K0}pi+)/\Gamma(D+->K-pi+pi+) = (30.60 +/- 0.46 +/- 0.32)%,
\Gamma(D+->\bar{K0}K+)/\Gamma(D+->K-pi+pi+) = (6.04 +/- 0.35 +/- 0.30)% and
\Gamma(D+->\bar{K0}K+)/\Gamma(D+->\bar{K0}pi+) = (19.96 +/- 1.19 +/- 0.96)%.Comment: 4 pages, 3 figure
A High Statistics Measurement of the Lambdac+ Lifetime
A high statistics measurement of the Lambdac+ lifetime from the Fermilab
fixed-target FOCUS photoproduction experiment is presented. We describe the
analysis technique with particular attention to the determination of the
systematic uncertainty. The measured value of 204.6 +/- 3.4 (stat.) +/- 2.5
(syst.) fs from 8034 +/- 122 Lambdac -> pKpi decays represents a significant
improvement over the present world average.Comment: Submitted to Physical Review Letter
A measurement of branching ratios of and hadronic decays to four-body final states containing a
We have studied hadronic four-body decays of and mesons with a
in the final state using data recorded during the 1996-1997 fixed-target
run at Fermilab high energy photoproduction experiment FOCUS. We report a new
branching ratio measurement of . We make the first observation
of three new decay modes with branching ratios ,
\Gamma(D^+\to\K_S K^+ K^-\pi^+)/\Gamma(D^+\to K_S
\pi^+\pi^+\pi^-)=0.0077\pm0.0015\pm0.0009, and , where
in each case the first error is statistical and the second error is systematic.Comment: 4 pages, 1 table, 2 figures, submitted to Physical Review Letter
A Measurement of the Ds+ Lifetime
A high statistics measurement of the Ds+ lifetime from the Fermilab
fixed-target FOCUS photoproduction experiment is presented. We describe the
analysis of the two decay modes, Ds+ -> phi(1020)pi+ and Ds+ ->
\bar{K}*(892)0K+, used for the measurement. The measured lifetime is 507.4 +/-
5.5 (stat.) +/- 5.1 (syst.) fs using 8961 +/- 105 Ds+ -> phi(1020)pi+ and 4680
+/- 90 Ds+ -> \bar{K}*(892)0K+ decays. This is a significant improvement over
the present world average.Comment: 5 pages, 3 figures, 2 tables, submitted to PR
New FOCUS results on charm mixing and CP violation
We present a summary of recent results on CP violation and mixing in the
charm quark sector based on a high statistics sample collected by
photoproduction experiment FOCUS (E831 at Fermilab). We have measured the
difference in lifetimes for the decays: and . This translates into a measurement of the mixing parameter in
the \d0d0 system, under the assumptions that is an equal mixture of
CP odd and CP even eigenstates, and CP violation is negligible in the neutral
charm meson system. We verified the latter assumption by searching for a CP
violating asymmetry in the Cabibbo suppressed decay modes , and . We show preliminary
results on a measurement of the branching ratio .Comment: 9 pages, 6 figures, requires espcrc2.sty. Presented by S.Bianco at
CPConf2000, September 2000, Ferrara (Italy). In this revision, fixed several
stylistic flaws, add two significant references, fixed a typo in Tab.
Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaques.
Immunotherapies that induce durable immune control of chronic HIV infection may eliminate the need for life-long dependence on drugs. We investigated a DNA vaccine formulated with a novel genetic adjuvant that stimulates immune responses in the blood and gut for the ability to improve therapy in rhesus macaques chronically infected with SIV. Using the SIV-macaque model for AIDS, we show that epidermal co-delivery of plasmids expressing SIV Gag, RT, Nef and Env, and the mucosal adjuvant, heat-labile E. coli enterotoxin (LT), during antiretroviral therapy (ART) induced a substantial 2-4-log fold reduction in mean virus burden in both the gut and blood when compared to unvaccinated controls and provided durable protection from viral rebound and disease progression after the drug was discontinued. This effect was associated with significant increases in IFN-γ T cell responses in both the blood and gut and SIV-specific CD8+ T cells with dual TNF-α and cytolytic effector functions in the blood. Importantly, a broader specificity in the T cell response seen in the gut, but not the blood, significantly correlated with a reduction in virus production in mucosal tissues and a lower virus burden in plasma. We conclude that immunizing with vaccines that induce immune responses in mucosal gut tissue could reduce residual viral reservoirs during drug therapy and improve long-term treatment of HIV infection in humans
Measurement of the relative branching ratio BR(\Xi_c^+ \to p^+ K^-\pi^+)\BR(\Xi_c^+ \to \Xi^- \pi^+ \pi^+)
We report the observation of the Cabibbo suppressed decay \Xi_c^+ \to p
K^-\pi^+ using data collected with the FOCUS spectrometer during the 1996--97
Fermilab fixed target run. We find a \Xi_c^+ signal peak of 202\pm35 events. We
have measured the relative branching ratios BR(\Xi^+_c\to p
K^-\pi^+)/BR(\Xi^+_c\to\Xi^-\pi^+\pi^+)= 0.234 \pm 0.047 \pm 0.022 and
BR(\Xi^+_c\to p \bar{K}^*(892)^0)/BR(\Xi^+_c\to p K^-\pi^+)= 0.54 \pm 0.09 \pm
0.05 .Comment: 9 pages, 4 figure
The Target Silicon Detector for the FOCUS Spectrometer
We describe a silicon microstrip detector interleaved with segments of a
beryllium oxide target which was used in the FOCUS photoproduction experiment
at Fermilab. The detector was designed to improve the vertex resolution and to
enhance the reconstruction efficiency of short-lived charm particles.Comment: 18 pages, 14 figure
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