Biochemistry and physiology of gastrointestinal somatostatin

Somatostatin, a tetradecapeptide initially isolated from the ovine hypothalamus, is widely distributed throughout the gastrointestinal tract where it may act as a hormone, local chemical messenger, or neurotransmitter to elicit many physiological actions. Release of somatostatin from D cells in the gut is regulated by mechanisms that are both dependent on and independent of cAMP. In most cases somatostatin acts to inhibit the function of its target cells. It performs this action in part via pertussis-toxin-sensitive inhibitory guanine nucleotide-binding proteins that regulate adenylate cyclase activity. Other mechanisms may involve sites of action distal to intracellular second messenger systems .Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44411/1/10620_2005_Article_BF01536041.pd

The hydrodynamics of high diving

Diving consists of jumping into water from a platform, usually while performing acrobatics. During high diving competitions, the initial height reaches 27 m. From this height, the crossing of the water surface occurs at 85 km/h, and as such it is very technical to avoid injuries. Major risks occur due to the violent impact at the water entry and the formation and collapse of the air cavity around the diver. In this study, we investigate experimentally the dynamics of the jumper underwater and the hydrodynamic causes of injuries in high dives by monitoring dives from different heights with high-speed cameras and accelerometers in order to understand the physics underlying diving