477 research outputs found
Understanding and protecting vulnerable financial consumers
This article considers how consumer protection law and policy should address the interests of particularly vulnerable financial consumers. Specifically, the article proposes a taxonomy of vulnerability which helps to identify (a) what makes consumers particularly vulnerable, and (b) how consumer protection law and consumer policy (broadly understood) can respond to these causes in a way that provides such consumers with appropriate protection. Changes to economic conditions, legal requirements on traders and our understanding of consumer behaviour make discussion of these issues particularly topical. There is little doubt that finding solutions is extremely difficult. Trade-offs are necessary and some enduring factors that contribute to vulnerability, in particular poverty, sometimes appear intractable. Nevertheless, it is submitted that by identifying clearly both why consumers are vulnerable and how the factors that lead to such vulnerability can be addressed, it is possible to construct an environment which respects consumer choice while ensuring that the most vulnerable are protected appropriately
A certain class of Laplace transforms with applications to reaction and reaction-diffusion equations
A class of Laplace transforms is examined to show that particular cases of
this class are associated with production-destruction and reaction-diffusion
problems in physics, study of differences of independently distributed random
variables and the concept of Laplacianness in statistics, alpha-Laplace and
Mittag-Leffler stochastic processes, the concepts of infinite divisibility and
geometric infinite divisibility problems in probability theory and certain
fractional integrals and fractional derivatives. A number of applications are
pointed out with special reference to solutions of fractional reaction and
reaction-diffusion equations and their generalizations.Comment: LaTeX, 12 pages, corrected typo
Carbon release by selective alloying of transition metal carbides
We have performed first principles density functional theory calculations on
TiC alloyed on the Ti sublattice with 3d transition metals ranging from Sc to
Zn. The theory is accompanied with experimental investigations, both as regards
materials synthesis as well as characterization. Our results show that by
dissolving a metal with a weak ability to form carbides, the stability of the
alloy is lowered and a driving force for the release of carbon from the carbide
is created. During thin film growth of a metal carbide this effect will favor
the formation of a nanocomposite with carbide grains in a carbon matrix. The
choice of alloying elements as well as their concentrations will affect the
relative amount of carbon in the carbide and in the carbon matrix. This can be
used to design the structure of nanocomposites and their physical and chemical
properties. One example of applications is as low-friction coatings. Of the
materials studied, we suggest the late 3d transition metals as the most
promising elements for this phenomenon, at least when alloying with TiC.Comment: 9 pages, 6 figure
Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule sensitivity
Fluorescent nucleobase analogues (FBAs) have many desirable features in comparison to extrinsic fluorescent labels, but they are yet to find application in ultrasensitive detection. Many of the disadvantages of FBAs arise from their short excitation wavelengths (often in the ultraviolet), making two-photon excitation a potentially attractive approach. Pentacyclic adenine (pA) is a recently developed FBA that has an exceptionally high two-photon brightness. We have studied the two-photon-excited fluorescence properties of pA and how they are affected by incorporation in DNA. We find that pA is more photostable under two-photon excitation than via resonant absorption. When incorporated in an oligonucleotide, pA has a high two-photon cross section and emission quantum yield, varying with sequence context, resulting in the highest reported brightness for such a probe. The use of a two-photon microscope with ultrafast excitation and pulse shaping has allowed the detection of pA-containing oligonucleotides in solution with a limit of detection of ∼5 molecules, demonstrating that practical single-molecule detection of FBAs is now within reach
HAG1 and SWI3A/B control of male germ line development in P. patens suggests conservation of epigenetic reproductive control across land plants
Bryophytes as models to study the male germ line: loss-of-function mutants of epigenetic regulators HAG1 and SWI3a/b demonstrate conserved function in sexual reproduction
Multi-user video streaming using unequal error protection network coding in wireless networks
In this paper, we investigate a multi-user video streaming system applying unequal error protection (UEP) network coding (NC) for simultaneous real-time exchange of scalable video streams among multiple users. We focus on a simple wireless scenario where users exchange encoded data packets over a common central network node (e.g., a base station or an access point) that aims to capture the fundamental system behaviour. Our goal is to present analytical tools that provide both the decoding probability analysis and the expected delay guarantees for different importance layers of scalable video streams. Using the proposed tools, we offer a simple framework for design and analysis of UEP NC based multi-user video streaming systems and provide examples of system design for video conferencing scenario in broadband wireless cellular networks
A Boost for the Emerging Field of RNA Nanotechnology: Report on the First International Conference on RNA Nanotechnology
This Nano Focus article highlights recent advances in RNA nanotechnology as presented at the First International Conference of RNA Nanotechnology and Therapeutics, which took place in Cleveland, OH, USA (October 23-25, 2010) (http;//www.eng.uc.edu/nanomedidne/RNA2010/), chaired by Peixuan Guo and co-chaired by David Rueda and Scott Tenenbaum. The conference was the first of its kind to bring together more than 30 invited speakers in the frontier of RNA nanotechnology from France, Sweden, South Korea, China, and throughout the United States to discuss RNA nanotechnology and Its applications. It provided a platform for researchers from academia, government, and the pharmaceutical industry to share existing knowledge, vision, technology, and challenges in the field and promoted collaborations among researchers interested in advancing this emerging scientific discipline. The meeting covered a range of topics, including biophysical and single-molecule approaches for characterization of RNA nanostructures; structure studies on RNA nanoparticles by chemical or biochemical approaches, computation, prediction, and modeling of RNA nanoparticle structures; methods for the assembly of RNA nanoparticles; chemistry for RNA synthesis, conjugation, and labeling; and application of RNA nanoparticles in therapeutics. A special invited talk on the well-established principles of DNA nanotechnology was arranged to provide models for RNA nanotechnology. An Administrator from National Institutes of Health (NIH) National Cancer Institute (NCI) Alliance for Nanotechnology in Cancer discussed the current nanocancer research directions and future funding opportunities at NCl. As indicated by the feedback received from the invited speakers and the meeting participants, this meeting was extremely successful, exciting, and informative, covering many groundbreaking findings, pioneering ideas, and novel discoveries
Consumer Law and Policy Relating to Change of Circumstances Due to the COVID-19 Pandemic
An unprecedented number of consumer problems has been caused by the COVID-19 pandemic, not least with regard to refunds of prepayments and the ability of consumers to keep up their monthly payments under loan and rental agreements. Based on a notion of societal force majeure sketched in this paper, we propose guiding principles in respect of the introduction of moratoria on recurring payments, the use of refunds or vouchers in respect of prepayments, and associated enforcement challenges. This analysis draws on experiences around the globe.Non peer reviewe
Fractional reaction-diffusion equations
In a series of papers, Saxena, Mathai, and Haubold (2002, 2004a, 2004b)
derived solutions of a number of fractional kinetic equations in terms of
generalized Mittag-Leffler functions which provide the extension of the work of
Haubold and Mathai (1995, 2000). The subject of the present paper is to
investigate the solution of a fractional reaction-diffusion equation. The
results derived are of general nature and include the results reported earlier
by many authors, notably by Jespersen, Metzler, and Fogedby (1999) for
anomalous diffusion and del-Castillo-Negrete, Carreras, and Lynch (2003) for
reaction-diffusion systems with L\'evy flights. The solution has been developed
in terms of the H-function in a compact form with the help of Laplace and
Fourier transforms. Most of the results obtained are in a form suitable for
numerical computation.Comment: LaTeX, 17 pages, corrected typo
Global compactness for a class of quasi-linear elliptic problems
We prove a global compactness result for Palais-Smale sequences associated
with a class of quasi-linear elliptic equations on exterior domains.Comment: 19 page
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