Analisis Daya Anestesi Bahan Alami Ekstrak Buah Keben (Barringtonia Asiatica) pada Ikan Bawal Bintang (Trachinotus Blochii)

The experiment was conducted at Marine Aquaculture Unit of UPTD Sub-District of Moro Fishery and Marine Office of Karimun Regency, Province ofKepulauan Riau on February to March 2017. Extraction stage was conducted atMarine Chemical Laboratory Department of Marine Science Faculty of Fisheriesand Marine University of Riau. This Study aims to obtain the optimalconcentration of extract Keben (Barringtonia asiatica) for the process ofimotilization of Silver Pompanoo Fish. The test animal used is Silver Pompanoo(Trachinotus blochii) with size 150-200 gr. On the basis of preliminary results, theexperiment were carried out with 4 treatment concentrations of 13,79 mg/l, 19,00mg/l, 26,00 mg/l, 35,50 mg/l, and 0 mg/l as controls. Anova test showed thatconcentration had significant effect (P<0,05) on induction time, recoveredconscious and survival rate of Silver Pompanoo. The results showed thatconcentration 13,79 mg/l was the optimal concentration for Silver Pompanooimotilization process with induction time ranged from 15-17 minutes andconscious recovering time around 4-5 minutes and long fainting for 4,5 hours andresulted in rate of life equal to 86,6%

Perancangan Interior Akademi Sepak Bola Di Malang Dengan Konsep “Beginning Team”

Football is one of the most popular sports in Indonesia. In reverse, Indonesian football is slumped by lack of achievement both domestically and Internationally. Indonesia has many talented young players. But not many soccer academies in Indonesia are able to develop these young players. Therefore, adequate facilities are needed that can support the development of young players talent.This design uses the method of collecting quantitative and qualitative data. The design method used is 3 stages, inspiration, ideation, and implementation. Academy soccer in Malang will be more emphasis on facilities that support the activities of students while in the academy. The main facilities are academic learning facilities, and soccer practice facilities. Other supporting facilities are public facilities and administrators. The design of this football academy will provide soccer practice and learning facilities for young Indonesian players

Controlled versus free breathing for multiple-breath nitrogen washout in asthma.

The lack of comparability in indices of ventilation heterogeneity between free- and controlled-breathing MBNW protocols is confirmed in asthma https://bit.ly/3lmri4A

Normal limits for oscillometric bronchodilator responses and relationships with clinical factors.

Introduction: We aimed to determine normal thresholds for positive bronchodilator responses for oscillometry in an Australian general population sample aged ≥40 years, to guide clinical interpretation. We also examined relationships between bronchodilator responses and respiratory symptoms, asthma diagnosis, smoking and baseline lung function. Methods: Subjects recruited from Sydney, Melbourne and Busselton, Australia, underwent measurements of spirometry, resistance (R rs6 ) and reactance (X rs6 ) at 6 Hz, before and after inhalation of salbutamol 200 μg. Respiratory symptoms and/or medication use, asthma diagnosis, and smoking were recorded. Threshold bronchodilator responses were defined as the fifth percentile of decrease in R rs6 and 95th percentile increase in X rs6 in a healthy subgroup. Results: Of 1318 participants, 1145 (570 female) were analysed. The lower threshold for ΔR rs6 was -1.38 cmH2O·s·L-1 (-30.0% or -1.42 Z-scores) and upper threshold for ΔX rs6 was 0.57 cmH2O·s·L-1 (1.36 Z-scores). Respiratory symptoms and/or medication use, asthma diagnosis, and smoking all predicted bronchodilator response, as did baseline oscillometry and spirometry. When categorised into clinically relevant groups according to those predictors, ΔX rs6 was more sensitive than spirometry in smokers without current asthma or chronic obstructive pulmonary disease (COPD), ∼20% having a positive response. Using absolute or Z-score change provided similar prevalences of responsiveness, except in COPD, in which responsiveness measured by absolute change was twice that for Z-score. Discussion: This study describes normative thresholds for bronchodilator responses in oscillometry parameters, including intra-breath parameters, as determined by absolute, relative and Z-score changes. Positive bronchodilator response by oscillometry correlated with clinical factors and baseline function, which may inform the clinical interpretation of oscillometry

Fluctuation analysis of lung function as a predictor of long-term response to beta2-agonists

The response to beta(2)-agonists differs between asthmatics and has been linked to subsequent adverse events, even death. Possible determinants include beta(2)-adrenoceptor genotype at position 16, lung function and airway hyperresponsiveness. Fluctuation analysis provides a simple parameter alpha measuring the complex correlation properties of day-to-day peak expiratory flow. The present study investigated whether alpha predicts clinical response to beta(2)-agonist treatment, taking into account other conventional predictors. Analysis was performed on previously published twice-daily peak expiratory flow measurements in 66 asthmatic adults over three 6-month randomised order treatment periods: placebo, salbutamol and salmeterol. Multiple linear regression was used to determine the association between alpha during the placebo period and response to treatment (change in the number of days with symptoms), taking into account other predictors namely beta(2)-adrenoceptor genotype, lung function and its variability, and airway hyperresponsiveness. The current authors found that alpha measured during the placebo period considerably improved the prediction of response to salmeterol treatment, taking into account genotype, lung function or its variability, or airway hyperresponsiveness. The present study provides further evidence that response to beta(2)-agonists is related to the time correlation properties of lung function in asthma. The current authors conclude that fluctuation analysis of lung function offers a novel predictor to identify patients who may respond well or poorly to treatment