274 research outputs found

    Network-based dissolution

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    We introduce a novel graph-theoretic dissolution model which applies to a number of redistribution scenarios such as gerrymandering or work economization. The central aspect of our model is to delete some vertices and redistribute their "load" to neighboring vertices in a completely balanced way. We investigate how the underlying graph structure, the pre-knowledge about which vertices to delete, and the relation between old and new "vertex load" influence the computational complexity of the underlying easy-to-describe graph problems, thereby identifying both tractable and intractable cases

    Momentum diffusion for coupled atom-cavity oscillators

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    It is shown that the momentum diffusion of free-space laser cooling has a natural correspondence in optical cavities when the internal state of the atom is treated as a harmonic oscillator. We derive a general expression for the momentum diffusion which is valid for most configurations of interest: The atom or the cavity or both can be probed by lasers, with or without the presence of traps inducing local atomic frequency shifts. It is shown that, albeit the (possibly strong) coupling between atom and cavity, it is sufficient for deriving the momentum diffusion to consider that the atom couples to a mean cavity field, which gives a first contribution, and that the cavity mode couples to a mean atomic dipole, giving a second contribution. Both contributions have an intuitive form and present a clear symmetry. The total diffusion is the sum of these two contributions plus the diffusion originating from the fluctuations of the forces due to the coupling to the vacuum modes other than the cavity mode (the so called spontaneous emission term). Examples are given that help to evaluate the heating rates induced by an optical cavity for experiments operating at low atomic saturation. We also point out intriguing situations where the atom is heated although it cannot scatter light.Comment: More information adde

    Equivariant cohomology and analytic descriptions of ring isomorphisms

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    In this paper we consider a class of connected closed GG-manifolds with a non-empty finite fixed point set, each MM of which is totally non-homologous to zero in MGM_G (or GG-equivariantly formal), where G=Z2G={\Bbb Z}_2. With the help of the equivariant index, we give an explicit description of the equivariant cohomology of such a GG-manifold in terms of algebra, so that we can obtain analytic descriptions of ring isomorphisms among equivariant cohomology rings of such GG-manifolds, and a necessary and sufficient condition that the equivariant cohomology rings of such two GG-manifolds are isomorphic. This also leads us to analyze how many there are equivariant cohomology rings up to isomorphism for such GG-manifolds in 2- and 3-dimensional cases.Comment: 20 pages, updated version with two references adde

    Inductive Learning of Simple Diagnostic Scores

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    Nuclear matrix element for two neutrino double beta decay from 136Xe

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    The nuclear matrix element for the two neutrino double beta decay (DBD) of 136Xe was evaluated by FSQP (Fermi Surface Quasi Particle model), where experimental GT strengths measured by the charge exchange reaction and those by the beta decay rates were used. The 2 neutrino DBD matrix element is given by the sum of products of the single beta matrix elements via low-lying (Fermi Surface) quasi-particle states in the intermediate nucleus. 136Xe is the semi-magic nucleus with the closed neutron-shell, and the beta + transitions are almost blocked. Thus the 2 neutrino DBD is much suppressed. The evaluated 2 neutrino DBD matrix element is consistent with the observed value.Comment: 7 pages 6 figure

    Ultracold atoms in optical lattices generated by quantized light fields

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    We study an ultracold gas of neutral atoms subject to the periodic optical potential generated by a high-QQ cavity mode. In the limit of very low temperatures, cavity field and atomic dynamics require a quantum description. Starting from a cavity QED single atom Hamiltonian we use different routes to derive approximative multiparticle Hamiltonians in Bose-Hubbard form with rescaled or even dynamical parameters. In the limit of large enough cavity damping the different models agree. Compared to free space optical lattices, quantum uncertainties of the potential and the possibility of atom-field entanglement lead to modified phase transition characteristics, the appearance of new phases or even quantum superpositions of different phases. Using a corresponding effective master equation, which can be numerically solved for few particles, we can study time evolution including dissipation. As an example we exhibit the microscopic processes behind the transition dynamics from a Mott insulator like state to a self-ordered superradiant state of the atoms, which appears as steady state for transverse atomic pumping.Comment: 17 pages, 10 figures, Published versio

    Cavity cooling of a single atom

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    All conventional methods to laser-cool atoms rely on repeated cycles of optical pumping and spontaneous emission of a photon by the atom. Spontaneous emission in a random direction is the dissipative mechanism required to remove entropy from the atom. However, alternative cooling methods have been proposed for a single atom strongly coupled to a high-finesse cavity; the role of spontaneous emission is replaced by the escape of a photon from the cavity. Application of such cooling schemes would improve the performance of atom cavity systems for quantum information processing. Furthermore, as cavity cooling does not rely on spontaneous emission, it can be applied to systems that cannot be laser-cooled by conventional methods; these include molecules (which do not have a closed transition) and collective excitations of Bose condensates, which are destroyed by randomly directed recoil kicks. Here we demonstrate cavity cooling of single rubidium atoms stored in an intracavity dipole trap. The cooling mechanism results in extended storage times and improved localization of atoms. We estimate that the observed cooling rate is at least five times larger than that produced by free-space cooling methods, for comparable excitation of the atom

    The 3q Oncogene SEC62 Predicts Response to Neoadjuvant Chemotherapy and Regulates Tumor Cell Migration in Triple Negative Breast Cancer

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    In the absence of targeted treatment options, neoadjuvant chemotherapy (NACT) is applied widely for triple-negative breast cancer (TNBC). Response to NACT is an important parameter predictive of oncological outcomes (progression-free and overall survival). An approach to the evaluation of predictive markers enabling therapy individualization is the identification of tumor driver genetic mutations. This study was conducted to investigate the role of SEC62, harbored at 3q26 and identified as a driver of breast cancer pathogenesis, in TNBC. We analyzed SEC62 expression in The Cancer Genome Atlas database, and immunohistologically investigated SEC62 expression in pre- and post-NACT tissue samples from 64 patients with TNBC treated at the Department of Gynecology and Obstetrics/Saarland University Hospital/Homburg between January 2010 and December 2018 and compared the effect of SEC62 on tumor cell migration and proliferation in functional assays. SEC62 expression dynamics correlated positively with the response to NACT (p ≤ 0.01) and oncological outcomes (p ≤ 0.01). SEC62 expression stimulated tumor cell migration (p ≤ 0.01). The study findings indicate that SEC62 is overexpressed in TNBC and serves as a predictive marker for the response to NACT, a prognostic marker for oncological outcomes, and a migration-stimulating oncogene in TNBC

    Retracts and retractile subcomplexes

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/33452/1/0000855.pd
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