5,748 research outputs found

    Reexamining the Racial Record of Abraham Lincoln

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    Since his death in 1865 Abraham Lincoln has been universally honored in black America. In many black homes and businesses, his photograph often hangs in honor next to the one of Martin Luther King Jr. But a new book by Ebony editor Lerone Bennett Jr. contends that Lincoln was a crude bigot who told demeaning darky jokes, had an unquenchable thirst for minstrel shows, consistently used the word nigger, and supported efforts to ship Negroes back to Africa. As Jack E. White pointed out in a recent Time magazine article, this book largely has been ignored by the mainstream press. The book was not reviewed in The Washington Post, The New Yorker, The Chicago Tribune, or USA Today. JBHE [Journal of Blacks in Higher Education] asked a group of leading Lincoln scholars for their opinions of the Bennett book and the controversy surrounding its publication. Here are the replies

    Golabi-Ito-Hall syndrome results from a missense mutation in the WW domain of the PQBP1 gene

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    Background: Golabi, Ito, and Hall reported a family with X linked mental retardation (XLMR), microcephaly, postnatal growth deficiency, and other anomalies, including atrial septal defect, in 1984.Methods: This family was restudied as part of our ongoing study of XLMR, but significant linkage to X chromosome markers could not be found. Extreme short stature and microcephaly as well as other new clinical findings were observed. Mutations in the polyglutamine tract binding protein 1 gene (PQBP1) have recently been reported in four XLMR disorders (Renpenning, Hamel cerebro-palato-cardiac, Sutherland-Haan, and Porteous syndromes) as well as in several other families. The clinical similarity of our family to these patients with mutations in PQBP1, particularly the presence of microcephaly, short stature, and atrial septal defect, prompted examination of this gene.Results: A missense mutation in PQBP1 was identified which changed the conserved tyrosine residue in the WW domain at position 65 to a cysteine (p.Y65C).Conclusions: This is the first missense mutation identified in PQBP1 and the first mutation in the WW domain of the gene. The WW domain has been shown to play an important role in the regulation of transcription by interacting with the PPxY motif found in transcription factors. The p.Y65C mutation may affect the proper functioning of the PQBP1 protein as a transcriptional co-activator

    Weighing the Need to Establish Regulatory Takings Doctrine to Justify Takings Standards of Review and Principles

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    This article revisits and examines whether the fairness and justice doctrine of Armstrong v. United States can justify and fashion standards of review to protect the right to just compensation of the Takings Clause. The Court has relied on Armstrong to show the purpose of the Takings Clause in many takings decisions. However, can Armstrong serve a greater purpose? In Dolan v. City of Tigard, the United States Supreme Court applied the unconstitutional conditions doctrine to justify the need for a standard of review to protect the right to just compensation. The Court transported questionable constitutional doctrine to validate Justice Holmes’s regulatory takings theory. Yet, in Tahoe-Sierra Preservation Council v. Tahoe Regional Planning Agency, the Court applied Armstrong’s fairness and justice doctrine to justify not applying standards of review to a complete range of factual theories of regulatory takings theory. Therefore, the Court leads one to ask whether the Armstrong fairness and justice doctrine should be considered in justifying the selection of standards of review and principles to protect the right to just compensation
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