Cordyla pinnata améliore les propriétés du sol et la productivité des cultures

Dans les systèmes agroforestiers, les cultures sous le couvert des arbres (SC) bénéficient de plus de nutriments, après décomposition et minéralisation des litières, que celles hors de leur couvert (HC). La fertilité des sols et la productivité du mil et de l’arachide ont été évaluées sur des sols prélevés à différentes distances de Cordyla pinnata, une légumineuse arborée qui forme un parc agroforestier au Sénégal. Les analyses de sols ont montré des valeurs plus élevées pour N total, Ca échangeable et CEC sous le couvert de l’espèce. Pour le mil, la hauteur, les biomasses aérienne et racinaire ont également été plus élevées sur les sols SC. Par conséquent, la biomasse totale du mil a fortement augmenté (+ 90%) sur les sols SC. Pour l’arachide, la longueur totale, les biomasses (tiges, feuilles, gousses, racines) ont été supérieures sur les sols SC. Comme pour le mil, la biomasse totale de l’arachide a augmenté (+ 94%) sur les sols SC par rapport au découvert. La plupart des variables des cultures ont été plus élevées sur les sols SC, probablement à cause de leur meilleur statut nutritif. L’introduction des arbres dans les systèmes de production au Sahel pourrait ainsi constituer une bonne stratégie pour améliorer la fertilité des sols et contribuer au développement d’une agriculture durable.Mots clés: Arachide, Fertilité des sols, Mil, Parc agroforestier, Sénéga

Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models

Processing by the proprotein convertase furin is believed to be critical for the biological activity of multiple proteins involved in hemostasis, including coagulation factor VIII (FVIII). This belief prompted the retention of the furin recognition motif (amino acids 1645-1648) in the design of B-domain-deleted FVIII (FVIII-BDD) products in current clinical use and in the drug development pipeline, as well as in experimental FVIII gene therapy strategies. Here, we report that processing by furin is in fact deleterious to FVIII-BDD secretion and procoagulant activity. Inhibition of furin increases the secretion and decreases the intracellular retention of FVIII-BDD protein in mammalian cells. Our new variant (FVIII-ΔF), in which this recognition motif is removed, efficiently circumvents furin. FVIII-ΔF demonstrates increased recombinant protein yields, enhanced clotting activity, and higher circulating FVIII levels after adeno-associated viral vector-based liver gene therapy in a murine model of severe hemophilia A (HA) compared with FVIII-BDD. Moreover, we observed an amelioration of the bleeding phenotype in severe HA dogs with sustained therapeutic FVIII levels after FVIII-ΔF gene therapy at a lower vector dose than previously employed in this model. The immunogenicity of FVIII-ΔF did not differ from that of FVIII-BDD as a protein or a gene therapeutic. Thus, contrary to previous suppositions, FVIII variants that can avoid furin processing are likely to have enhanced translational potential for HA therapy

2003 Wild Blueberry Project Reports

The 2003 edition of the Wild Blueberry Project Reports was prepared for the Wild Blueberry Commission of Maine and the Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: 1. Factors Affecting the Microbial and Pesticide Residues Levels on Lowbush Blueberries 2. Effect of Blueberry Products on Oxidation in Ground Beef Patties 3. Infestation Detection using Near-Infrared Spectroscopy 4. Whole Wild Blueberries and Arterial Functional Properties 5. Irrigation Water use in Wild Blueberry Production 7. Control Tactics for Blueberry Pest Insects 8. IPM Strategies 9. Biology and Ecology of Blueberry Pest Insects, 2003 10. Wild Blueberry Pollination Research 11. Stem Blight/Dieback and Leaf Spot Diseases in Wild Blueberry Fields 12. Effect of Foliar N spray on Leaf N Concentration, Growth and Yield of Wild Blueberries 13. Effect of Foliar Spray (4-13-15) on Leaf Nutrient Concentration, Growth and Yield of Wild Blueberries 14. Effect of Foliar Copper Application on Growth and Yield of Wild Blueberries 15. Effect of Foliar Copper and/or Iron Application on Growth and Yield of Wild Blueberries 16. Effect of Soil pH on Nutrient Uptake. 17. Effect of Gibberellic Acid (GA3) and CPPU on Fruit Set and Yield of Wild Blueberry after low temperature flower stress 18. Effect of Fertilizer Timing (prune year vs. crop year) on Wild Blueberry Growth and Productivity. 19. Assessment of Hexazinone Alternatives for Weed Control in Wild Blueberries and Weed Control and Field Cover Program Base 20. Evaluation of Fall Applications of Sulfonylurea Herbicides for Bunchberry Control in Wild Blueberries 21. Assessment of clean-cut adapter on hand clippers for weed control in wild blueberries 22. Evaluation and Demonstration of Techniques for Filling in Bare Spots in Wild Blueberry Fields 23. Blueberry Extension Education Program in 2003 24. 2003 Pesticide Groundwater Survey 25. Cultural Weed Management using Sulfur to lower the p

2001 Wild Blueberry CSREES Project Reports

The 2001 edition of the Wild Blueberry CSREES Progress Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: 1. Effect of Wild Blueberry Products on Oxidation in Meat Based Food Systems 2. Factors Affecting the Microbial and Pesticide Residues Levels on Wild Blueberries 3. Determination of Pesticide Residue Levels in Fresh and Processed Wild Blueberries 4. Separation of Maggot-Infested Wild Blueberries in the IQF Processing Line 5. Water Use of Wild Blueberries and the Impact of Plant Water Stress on Yields 6. Survey of Stem Blight and Leaf Spot Diseases in Wild Blueberry Fields 7. IPM Strategies 8. Control Tactics for Wild Blueberry Pest Insects, 2001 9. Biology and Ecology of Blueberry Pest Insects 10. Diurnal Bee Activity and Measurement of Honeybee Field Strength 11. Effect of Foliar-applied Iron (Fe) Chelate Concentration on Leaf Iron Concentration, Wild Blueberry Growth and Yield 12. Effect of Boron Application Methods on Boron Uptake in Wild Blueberries 13. Effect of Foliar Iron and Copper Application on Growth and Yield of Wild Blueberries 14. Effect of Fertilizer Timing on Wild Blueberry Growth and Productivity 15. Effect of Foliar Copper Application on Growth and Yield of Wild Blueberries 16. Effect of Prune-year Applications of Nutri-Phitetm P or Nutri-Phitetm P+K on Growth and Yield of Wild Blueberry (Vaccinium angustifolium Ait.) 17. Effect of Soil pH on Nutrient Uptake 18. Assessment of Azafenidin for Weed Control in Wild Blueberries 19. Assessment of Rimsulfuron for Weed Control in Wild Blueberries 20. Assessment of Pendimethalin for Weed Control in Wild Blueberries 21. Evaluation and Demonstration of Techniques for Filling in Bare Spots in Wild Blueberry Fields 22. Assessment of Sprout-less Weeder for Hardwood Control in Wild Blueberries 23. Wild Blueberry Extension Education Program in 2001 24. Evaluation of Fungicide Efficacy in Wild Blueberry Fields 25. 2001 Pesticide Groundwater Survey 26. Cultural Weed Management Using Sulfur to Lower the pH 27. Wild Blueberry Web Sit

1994 CSRS Research Reports/1994 Blueberry Tax Reports

The 1994 edition of the CSRS Research Reports/Blueberry Tax Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: CSRS Research Reports 1. Potential Uses for Green and Red Cull Blueberries 2. Preventing the Bleeding of Blueberry Fruit in Bakery Products 3. The Effect of Fertilization and Irrigation on Blueberry Fruit Quality 4. Determination of Pesticide Residue Levels in Freshly Harvested and Processed Lowbush Blueberries 5. The Effect of Mechanical Harvesting on Blueberry Fruit Quality 6. Removing Water from Blueberries Before Freezing 7. Application of Heat as a Method of Controlling Secondary Pest Insects in Lowbush Blueberries 8. Evaluation of Effectiveness of Eumenid Wasps for Biocontrol of Blueberry Pests 9. Pollination Ecology of Lowbush Blueberry in Maine 10. Fungicide Treatment for Control of Monilinia Blight 11. Field Sanitation for Control of Monilinia Blight 12. Cold-hardiness of Native Lowbush Blueberry 13. Phosphorus Dose/Response Curve 14. Multiple Cropping of Wild Blueberry Stands 15. Effect of Soil pH on Nutrient Uptake 16. Effect of Boron and Calcium on Lowbush Blueberry Fruit Set and Yield 17. Effect of Time of Fall Pruning on Growth and Productivity of Lowbush Blueberries 18. A Reinvestigation of the Economics of Mechanical Harvesting 19. Thresholds of Mechanical and Chemical Weed Controls in Wild Blueberries 20. Evaluation of Pressurized Rope Wick Master Wiper for Treating Weeds Growing Above Lowbush Blueberries 21. Evaluation of Infrared Burner for Selective Weed Control Blueberry Tax Reports 22. Control of Blueberry Pest Insects 23. Biology and Action Thresholds of Secondary Blueberry Pest Insects 24. Pollination Ecology of Low bush Blueberry in Maine 25. Nitrogen-Phosphorus Study 26. Evaluation of Pronone 10G for Control of Weeds in Lowbush Blueberries 27. Evaluation of Tribenuron Methyl for Bunchberry Control 28. Evaluation of Pendimethalin for Control of Annual Grasses in Lowbush Blueberries 29. Evaluation of Time of Application of Clopyralid for Control of Vetch, and Effect on Flowering of Lowbush Blueberries 30. Hexazinone Ground Water survey 31. Blueberry Extension Program Base 32. Blueberry ICM Program for Hancock Count

1993 Progress Reports

The 1993 Progress Reports which contain Blueberry Tax Supported Weed Management and Pruning Project Reports, and CSRS Supported Weed Management and Pruning Project Reports, pertain to and report on research conducted in 1992. They were prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: Progress Reports 1. Effects of Irrigation on Low bush Blueberry Yield and Quality 2. Economics of Investing in Irrigation for Lowbush Blueberries 3. Diammonium Phosphate Study 4. Phosphorus Dose/Response Curve 5. Winter Injury Protection by Potassium 6. Multiple Cropping of Wild Stands 7. Effect of Boron on Lowbush Blueberry Fruit Set and Yield 8.Determination of Pesticide Residue Levels in Freshly Harvested and Processed Lowbush Blueberries 9. Effects of Calcium Salts and Citric Acids on the Quality of Canned Lowbush Blueberries- missing 10. Investigation of PreProcess Changes- missing 11. The Effect of Fertilization and Irrigation on Blueberry Fruit Control - missing 12. Pollination Ecology of Lowbush Blueberry in Maine 13. Control of Secondary Blueberry Pests 14. Control of Blueberry Maggot 15. Biology and Action Thresholds of Secondary Blueberry Pests 16. Cold-Hardiness of Native Lowbush Blueberries 17. Design, Fabrication, and Testing of an Experimental Sterilizer for Blueberry Fields 18. Canned Product Quality - Heat Resistant Molds 19. Sanitation for Disease Control Blueberry Tax Supported Weed Management and Pruning Project Reports 20. Evaluation of Postemergence Applications of Tribenuron Methyl for Bunchberry Control 21. Comparison of Poast and Select for Suppression of Bunchgrass 22. Effect of Time of Fall Pruning on Growth and Productivity of Blueberries. and Evaluation of Infrared Burner to Prune Blueberries 23. Evaluation of Velpar impregnated DAP for weed control 24. Thresholds of Dogbane and Bracken Fern for Mechanical and Chemical Control in Lowbush Blueberry Fields 25. Effect of Time and Rate of Application of Clopyralid for Control of Vetch in Lowbush Blueberries 26. Hexazinone Ground Water Survey 27. Composting Blueberry Processing Waste 28. Hexazinone Movement in a Blueberry Soil in Maine CSRS Supported Weed Management and Pruning Project Reports 29. Evaluation of the Suitability of Remote Sensing to Evaluate Plant Cover in Lowbush Blueberry Fields 30. Obstruction Removal in Lowbush Blueberry Fields 31. Evaluation of Pressurized Rope Wick Wick Master Wiper for Treating Weeds Growing Above Lowbush Blueberries 32. Evaluation of Infrared Burner for Weed Control 33. Blueberry Extension Education Program Base Miscellaneous 34. Comparison of N, NP, and NPK Fertilizers to Correct Nitrogen and Phosphorus Deficienc

Maine Blueberry Advisory Committee Research Report

The 1990 edition of the Maine Blueberry Advisory Committee Research Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers with the Maine Agricultural Experiment Station and Maine Cooperative Extension Service at the University of Maine, Orono. Projects in this report include: 1. Biology and action thresholds of secondary blueberry pests 2. Control of blueberry maggot 3. Control of secondary blueberry pests 4. Application of steam as a method of controlling secondary pest insects on lowbush blueberry: a feasibility study 5. Pollination of the lowbush blueberry by native bees 6. Nitrogen-phosphorus study 7. Potassium study 8. Multiple cropping of wild stands 9. Phosphorus dose/response curve 10. Improvement in the color and texture of the canned blueberry 11. The effect of fertilization and irrigation on blueberry fruit quality 12. Investigation of preprocess changes (chemical, microbiological, and/or physical) that could lead to the development of a simple and inexpensive method to measure preprocess berry spoilage 13. The effect of postharvest handling on the dietary fiber and ellagic acid content of lowbush blueberries 14. Determination of pesticide residue levels in freshly harvested and processed lowbush blueberries 15. Evaluation of Defoliating Diseases 16. Vacuum Sanitation for Disease Control 17. Evaluation and modification of commercial herbicide applications 18. Evaluation of the suitability of remote sensing to evaluate plant cover in lowbush blueberry fields 19. Evaluation of Sethoxydin (POAST) in lowbush blueberry fields 20. Seedling pruning study 21. Evaluation of norflurazon (SOLICAM) with or without hexazinone (VELPAR) for bunchberry control 22. Selective wiper and mechanical control of dogbane and bracken fern 23. Evaluation of norflurazon (SOLICAM) in fall vs spring for oatgrass control 24. Evaluation of sulfonyl urea herbicides for bunchberry control 25. Evaluation of postemergence applications of DPX-L5300 for bunchberry control 26. Effect of time of application and formulation of hexazinone (VELPAR) on blueberry and bunchberry 27. Investigations of lowbush blueberry fruit-bud cold hardiness 28. The economics of investing in irrigation for lowbush blueberries 29. Effects of irrigation on lowbush blueberry yield and quality 30. Groundwater and surface water development for blueberry irrigation 31. Design, fabrication and testing of an experimental sterilizer for blueberry field

1992 Blueberry Research Progress Reports

The 1992 Blueberry Research Progress Reports pertain to and report on research conducted in 1991, and were prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: 1992 CSRS Progress Reports: 1. Investigation of Groundwater Resources 2. Sprinkler Irrigation 3. Investigation of Preprocess Changes Leading to Berry Spoilage 4. Effect of Fertilization and Irrigation on Blueberry Quality 5. Effects of Calcium Salts and Citric Acid on Quality of Canned Lowbush Blueberries 6. Pollination of Lowbush Blueberry by Native Bees 7. Application of Heat for Controlling Insects 8. Investigations of Lowbush Blueberry Fruit Bud Cold-Hardiness 9. Steam Sterilization in Lowbush Blueberry Fields 10. Heat-Tolerant Molds 11. Vacuum Sanitation for Disease Control 12. Evaluation of Infrared Burner for Weed Control 13. Evaluation and Modification of Commercial Herbicide Wipers 14. Evaluation of Remote Sensing to Estimate Plant Cover in Lowbush Blueberry Fields 15. Comparison of Three Mechanical Blueberry Harvesters vs. Hand Raking Advisory Committee Research Reports: 16. Biology and action thresholds of secondary blueberry insects 17. Control of secondary blueberry pests 18. Control of blueberry maggot 19. Effects of calcium salts and citric acid on the quality of canned lowbush blueberries 20. The effects of postharvest handling on the dietary fiber and ellagic acid content of lowbush blueberries 21. Investigation of preprocessing changes that could lead to development of simple and inexpensive method to measure preprocessing berry spoilage 22. Determination of pesticide residue levels in fresh and processed lowbush blueberries 23. Vacuum sanitation for disease control 24. Heat-tolerant molds 25. Seedling pruning study 26. Effect of time and rate of application of Clopyralid for control of Vetch in lowbush blueberries 27. Evaluation and modification of commercial herbicide wipers 28. Effect of time of application and formulation of Hexazinone (Velpar) on Blueberry and Bunchberry 29. Evaluation of postemergence applications of Tribenuron Methyl for Bunchberry control 30. Thresholds of Dogbane and Bracken Fern by mechanical and chemical control in lowbush blueberry fields 31. Evaluation of the suitability of remote sensing to evaluate plant cover in lowbush blueberry fields 32. Evalution of infrared burner for weed control 33. Effect of time of fall pruning on growth and productivity of blueberry and evaluation of infrared burner to prune blueberries 34. Effect of Boron on lowbush blueberry fruit set and yield 35. Winter injury protection by potassium 36. Multiple cropping of wild stands 37. Nitrogen-Phosphorus study 38. Phosphorus dose/response curve 39. Investigations of lowbush blueberry fruit bud cold-hardines

1993-94 Progress Report

The 1993 edition of the Progress Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include: 1. Effects of irrigation on lowbush blueberry yield and quality 2. The Economics of investigating irrigation for lowbush blueberries 3. Phosphorus dose/response curve 4. Winter injury protection by potassium 5. Multiple cropping of wild stands 6. Effect of Boron and Calcium on lowbush blueberry fruit set and yield 7. Comparison of N, NP, and NPK fertilizers to correct nitrogen and phosphorus deficiency 8. Determination of pesticide residue levels in freshly harvested and processed lowbush blueberries 9. Effects of calcium salts and citric acid on the quality of canned lowbush blueberries 10. Investigation of preprocess changes (chemical, microbiological, and/or physical) that can lead to the development of a simple and inexpensive method to measure preprocess berry spoilage 11. The effect of fertilization and irrigation in blueberry fruit quality 12. Pollination Ecology of lowbush blueberry in Maine 13. Current importance of insects in lowbush blueberry fields 14. Application of heat as a method of controlling secondary pest insects on lowbush blueberry: a feasibility study 15. Control of blueberry maggot 16. Control of secondary blueberry pest insects 17. Biology and action thresholds of secondary blueberry pest insects 18. Cold-hardiness of native lowbush blueberry 19. Design, fabrication, and testing of an experimental sterilizer for blueberry fields 20. Canned Product Quality--Heat-resistant molds 21. Sanitation for disease control 22. Evaluation of Velpar® impregnated DAP and Pronone® for weed control 23. Evaluation of postemergence applications of tribenuron methyl for bunchberry control 24. Evaluation of postemergence applications of a tank mix of tribenuron methyl and hexazinone for bunchberry control 25. Thresholds of dogbane and bracken fem by mechanical and chemical control in lowbush blueberry fields 26. Effect of time of application of clopyralid for control of vetch and effect on flowering in lowbush blueberries 27. Effect of time of fall pruning on growth and productivity of blueberries and evaluation of infrared burner to prune blueberries 28. Evaluation of infrared burner for selective seedling weed control 29. Evaluation of pressurized rope wick Wick Master wiper for treating weeds growing above lowbush blueberries 30. Blueberry Extension Education Program Base 31. Blueberry ICM program for Hancock County 32. Composting blueberry processing waste 33. Hexazinone ground water survey 34. Investigations of Lowbush Blueberry Fruit bud Cold-hardiness 35. Design, Fabrication, and Testing of an Experimental Sterilizer for Blueberry Field