The `bare' strange stars might not be bare

It is proposed that the `bare' strange matter stars might not be bare, and radio pulsars might be in fact `bare' strange stars. As strange matter stars being intensely magnetized rotate, the induced unipolar electric fields would be large enough to construct magnetospheres. This situation is very similar to that discussed by many authors for rotating neutron stars. Also, the strange stars with accretion crusts in binaries could act as X-ray pulsars or X-ray bursters. There are some advantages if radio pulsars are `bare' strange stars.Comment: 11 pages, 1 Postscript figures, LaTeX, Chin. Phys. Lett. 1998, Vol.15, Nov.12, p.93

Towards reduction of type II theories on SU(3) structure manifolds

We revisit the reduction of type II supergravity on SU(3) structure manifolds, conjectured to lead to gauged N=2 supergravity in 4 dimensions. The reduction proceeds by expanding the invariant 2- and 3-forms of the SU(3) structure as well as the gauge potentials of the type II theory in the same set of forms, the analogues of harmonic forms in the case of Calabi-Yau reductions. By focussing on the metric sector, we arrive at a list of constraints these expansion forms should satisfy to yield a base point independent reduction. Identifying these constraints is a first step towards a first-principles reduction of type II on SU(3) structure manifolds.Comment: 20 pages; v2: condition (2.13old) on expansion forms weakened, replaced by (2.13new), (2.14new

A Climatology of Northwest Missouri Snowfall Events: Long Term Trends and Interannual Variability.

The goal of this study was to develop a 50-year statistical climatology of snowfall occurrences using data from a dense network of cooperative station observations covering northwest and central Missouri, and these records were provided by the Missouri Climate Center. This included a study of the long term trends and interannual variability in snowfall occurrence as related to sea surface temperature variations in the Pacific Ocean basin associated with the El Nino and Southern Oscillation (ENSO) and the North Pacific Oscillation (NPO). These trends and variations were then related to four synoptic-scale flow regimes that produce these snowfalls in the Midwest. The results demonstrate that during the snowfall season (Oct - April) the northwest Missouri region can expect about eight snowfall events which produce three or more inches of accumulation. While no significant long-term trend in overall snowfall occurrence was found, a decrease in the number of extreme events (10 or more inches) was noted. Also, fewer snowfall events were found during El Nino years, while more heavy snowfall events occurred during "neutral" years, and these results could be related to synoptic- scale variability. A closer examination of the results demonstrated that El Nino/La Nina related variability in snowfall occurrence was superimposed on longer-term NPO-related variability.This research was supported by the University Corporation for Atmospheric Research (UCAR) Cooperative program for Operational Meteorological Education and Training (COMET) Outreach Programunder award # 98115921

A forward genetic screen identifies host factors that influence the lysis-lysogeny decision in phage lambda

The lysis‐lysogeny decision made by bacteriophage lambda is one of the classic problems of molecular biology. Shortly after infecting a cell, the virus can either go down the lytic pathway and make more viruses, or go down the lysogenic pathway and integrate itself into the host genome. While much is known about how this decision takes place, the extent to which host physiology influences this decision and the mechanisms by which this influence takes place has remained mysterious. To answer this question, we performed a forward genetic screen to systematically identify all of the genes in E. coli that influence the lysis‐lysogeny decision. Our results demonstrate previously unknown links between host physiology and viral decision making and shed new light on this classic system

The ancestry of eastern paraguay: A typical south american profile with a unique pattern of admixture

Immigrants from diverse origins have arrived in Paraguay and produced important demographic changes in a territory initially inhabited by indigenous Guarani. Few studies have been performed to estimate the proportion of Native ancestry that is still preserved in Paraguay and the role of females and males in admixture processes. Therefore, 548 individuals from eastern Paraguay were genotyped for three marker sets: mtDNA, Y-SNPs and autosomal AIM-InDels. A genetic homogeneity was found between departments for each set of markers, supported by the demographic data collected, which showed that only 43% of the individuals have the same birthplace as their parents. The results show a sex-biased intermarriage, with higher maternal than paternal Native American ancestry. Within the native mtDNA lineages in Paraguay (87.2% of the total), most haplogroups have a broad distribution across the subcontinent, and only few are concentrated around the Paraná River basin. The frequency distribution of the European paternal lineages in Paraguay (92.2% of the total) showed a major contribution from the Iberian region. In addition to the remaining legacy of the colonial period, the joint analysis of the different types of markers included in this study revealed the impact of post-war migrations on the current genetic background of Paraguay.Funding: F.S. and L.G. were supported by Fundação de Amparo à Pesquisa do Rio de Janeiro–FAPERJ, Brazil (process E-26/202.275/2019 and CNE-2018). L.G. was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico–CNPq, Brazil (ref. 306342/2019-7). V.G. is supported by FCT under the program contract provided in Decree-Law no.57/2016 of August 29

Heterotic-type IIA duality with fluxes

In this paper we study a possible non-perturbative dual of the heterotic string compactified on K3 x T^2 in the presence of background fluxes. We show that type IIA string theory compactified on manifolds with SU(3) structure can account for a subset of the possible heterotic fluxes. This extends our previous analysis to a case of a non-perturbative duality with fluxes.Comment: 26 pages, minor corrections; version to appear in JHE

Mortality Rates Among Trichlorophenol Workers With Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

The authors examined 1,615 workers exposed to dioxins in trichlorophenol production in Midland, Michigan, to determine if there were increased mortality rates from exposure. Historical dioxin levels were estimated by a serum survey of workers. Vital status was followed from 1942 to 2003, and cause-specific death rates and trends with exposure were evaluated. All cancers combined (standardized mortality ratio (SMR) = 1.0, 95% confidence interval (CI): 0.8, 1.1), lung cancers (SMR = 0.7, 95% CI: 0.5, 0.9), and nonmalignant respiratory disease (SMR = 0.8, 95% CI: 0.6, 1.0) were at or below expected levels. Observed deaths for leukemia (SMR = 1.9, 95% CI: 1.0, 3.2), non-Hodgkin lymphoma (SMR = 1.3, 95% CI: 0.6, 2.5), diabetes (SMR = 1.1, 95% CI: 0.6, 1.8), and ischemic heart disease (SMR = 1.1, 95% CI: 0.9, 1.2) were slightly greater than expected. No trend was observed with exposure for these causes of death. However, for 4 deaths of soft tissue sarcoma (SMR = 4.1, 95% CI: 1.1, 10.5), the mortality rates increased with exposure. The small number of deaths and the uncertainty in both diagnosis and nosology coding make interpretation of this finding tenuous. With the exception of soft tissue sarcoma, the authors found little evidence of increased disease risk from exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

The Temporal and Spatial Connectivity of the Gambles Mill Corridor, Richmond, VA

The City of Richmond and the Virginia Department of Transportation proposed to rehabilitate the Gambles Mill Trail connecting the University of Richmond (UR) to the intersection of Huguenot and River Road. Planners envision this trail as a sustainable model for the reduction of nutrient and sediment flow and as a vital path in a city-wide network of bike and pedestrian trails. Meanwhile, UR also proposes to rehabilitate the corridor in their new Master Plan. Nevertheless, until now, no substantive studies exist on the trail or the corridor linking the trail to the south side of the James River through the hazardous River-Huguenot Road intersection and the Huguenot Bridge currently under construction. The University of Richmond’s Geography 221 Course, Mapping Sustainability: Cartography and Geographic Information in an Environmental Context, is working with a variety of stakeholders (public, private, and community-based) to map the past, present, and future of the Gambles Mill Corridor and influence local and regional sustainability of transportation, hydrology, and recreation in a floodplain ecosystem. Students produce maps grouped around four scales: local corridor, UR to the River, a city scale sustainable transport network, and a temporal scale tracing previous transportation routes in the area such as the 1930s street car system and the colonial canal system.https://scholarship.richmond.edu/geography-posters/1001/thumbnail.jp

Patient Perspectives on Chronic Rhinosinusitis in cystic fibrosis: Symptom prioritization in the era of highly effective modulator therapy

Background Chronic rhinosinusitis (CRS) is common in people with cystic fibrosis (PwCF). Rhinologic symptom prioritization and areas that influence CRS treatment choices, including pursuing endoscopic sinus surgery (ESS), remain understudied. Methods Adult PwCF + CRS were enrolled at eight centers into a prospective, observational study (2019–2023). Participants were administered the 22-SinoNasal Outcome Test (SNOT-22) survey and a modified SNOT-22 instrument examining symptom importance. We determined importance rankings for individual symptoms and SNOT-22 symptom importance subdomains in two sets of subgroups—those pursuing ESS versus continuing medical management (CMT), and those on elexacaftor/tezacaftor/ivacaftor (ETI) versus not on ETI. Results Among 69 participants, the highest priorities were nasal congestion (n = 48, 69.6% important), post-nasal discharge (32, 46.4%), facial pain (29, 43.3%), waking up tired (27, 39.1%), and fatigue (26, 37.7%). Those electing surgery (n = 23) prioritized sleep and psychological dysfunction symptoms compared to those pursuing CMT (n = 49) (sleep median score = 19.0 [interquartile range: 12.0, 25.0] vs. 4.5 [0.0, 12.8]; p \u3c 0.0001; psychological = 17.0 [7.0, 26.0] vs. 7.0 [0.0, 15.8]; p = 0.002). ETI users had comparable SNOT-22 total symptom importance scores to non-ETI users (p = 0.14). Non-ETI users (n = 34) showed a trend toward prioritizing sleep symptoms compared to ETI users (n = 35) (13.0 [2.8, 22.3] vs. 6.0 [2.0, 17.0]; p = 0.055). Conclusions Nasal congestion and post-nasal discharge were top priorities reported by PwCF + CRS. Those electing surgery prioritized sleep and psychological symptoms, highlighting their importance in pre-operative discussions. Non-ETI users’ prioritization of sleep improvement may highlight their unique disease impact and therapeutic needs; however, additional investigation is required