Single fibre action potentials in skeletal muscle related to recording distances

Single muscle fibre action potentials (SFAPs) are considered to be functions of a bioelectrical source and electrical conductivity parameters of the medium. In most model studies SFAPs are computed as a convolution of the bioelectrical source with a transfer function. Calculated peak-to-peak amplitudes of SFAPs decrease with increasing recording distances. In this paper an experimental validation of model results is presented. Experiments were carried out on the m. extensor digitorum longus (EDL) of the rat. Using a method including fluorescent labelling of the active fibre, the distance between the active fibre and the recording electrode was derived. With another method, the decline of the peak-to-peak amplitude of SFAPs detected along a multi-electrode was obtained. With both experimental methods, in general peak-to-peak amplitudes of SFAPs decreased with increasing recording distances, as was found in model results with present volume conduction theory. However, this behaviour was not found in all experiments. The rate of decline of the peak-to-peak amplitudes with recording distance was always less than in models

Case management for child protection services:A multi-level evaluation study

This article presents an evaluation study of a case management method for child protection services, the Delta Method for Family Supervision, in terms of supervision order duration and occurrence and duration of out-of-home placements. Additionally, case and case manager characteristics were examined. Data was collected about 224 cases, 58 case managers and 30 team managers of all 15 offices of the Child and Youth Protection Services in the Netherlands. In all cases the Delta Method was applied. Data were obtained by interviews, questionnaires and case files. Multi-level analysis was performed to study the influence of independent variables on supervision order duration, and the occurrence and duration of out-of-home placements. Case characteristics related to 87% of the differences in the duration of supervision order, case manager characteristics to 13% of the differences. Some case manager characteristics about applying the Delta Method were significantly related to shorter duration of the supervision order and the occurrence and duration of out-of-home placement. Case characteristics also showed strong relations. Together with the more general aspects of case management supported by this study, such as a one family and one worker approach, this contributes to a more effective practice of case management for child protection services

Measuring program fidelity in case management for high risk families. Validation of the Functional Family Parole-Global Rating Measure

Abstract Summary: Program fidelity instruments are a key ingredient for clinical supervision and implementation as well as effectiveness studies. This study examines the factor structure of the Functional Family Parole services Global Rating Measure (FFP-GRM); the program fidelity instrument of Functional Family Parole services for case management in youth parole, child protection and child welfare services. Between October 2012 and February 2015, program fidelity was measured with the FFP-GRM by Functional Family Parole supervisors. Confirmatory factor analysis was performed on 380 cases and internal consistency reliability coefficients were calculated. Findings: Confirmatory factor analyses showed that the 33-item and four-factor model of the FFP-GRM achieved a good fit to the data. Internal validity testing results showed that subscale Cronbach’s a ranged between .82 and .90. Applications: Findings affirm a good fit to the data and a good-to-excellent internal consistency of the FFP-GRM, which is considered sufficient to justify its use. The results are discussed with regard to the use of fidelity instruments for both clinical and research purposes

Закон України «Про позашкільну освіту» (витяг)

All around the world, paleovalley systems have trapped great amounts of deposits and hold a quite complete Late Quaternary record. Uniquely, these records directly interlink the shelf marine with the hinterland fluvial realms. In the vicinity of ice sheets, in similar ways, paleovalleys interlink the glacial record with the non-glacial domain. Considerable advances have been made in their study over the past decades, and many case well-dated and well-mapped case studies are now available. The means for comparison of records from older glacials and interglacials with that of the youngest ones have also improved. To further improve our understanding of the paleovalley systems, it is timely to start to intercompare the many cases at the new obtained resolutions. This is a correlation exercise in which we can make use of our established chronologies, sea-level histories, sedimentary evolution, human impact history and what is more. This is not just needed for the paleovalley system research itself, but also to unlock the records from the lower reaches of rivers and of deltas, estuaries and shelf areas for global research questions (climate responses and feedbacks, sediment fluxes, chronostratigraphy). This session introduction will give a quick tour around a series of events holding large correlation potential, via downstream and via upstream controls. E.g. the recording of transgression and high stand in the Last Interglacial and the Holocene, of regressions and low stands in the Last Glacial and earlier, of sustained climatic amelioration and deterioration at Milanković-scales, of shorter-lived events. Some of these correlation targets will work better than others, and case-to-case differences in performance are expected, as the presentations and discussions in the further session hopefully will sho

Corrigendum: Pleistocene Rhine–Thames landscapes: geological background for hominin occupation of the southern North Sea region

This paper links research questions in Quaternary geology with those in Palaeolithic archaeology. A detailed geological reconstruction of The Netherlands' south-west offshore area provides a stratigraphical context for archaeological and palaeontological finds. Progressive environmental developments have left a strong imprint on the area’s Palaeolithic record. We highlight aspects of landscape evolution and related taphonomical changes, visualized in maps for critical periods of the Pleistocene in the wider southern North Sea region. The Middle Pleistocene record is divided into two palaeogeographical stages: the pre-Anglian/Elsterian stage, during which a wide land bridge existed between England and Belgium even during marine highstands; and the Anglian/Elsterian to Saalian interglacial, with a narrower land bridge, lowered by proglacial erosion but not yet fully eroded. The Late Pleistocene landscape was very different, with the land bridge fully dissected by an axial Rhine–Thames valley, eroded deep enough to fully connect the English Channel and the North Sea during periods of highstand. This tripartite staging implies great differences in (i) possible migration routes of herds of herbivores as well as hominins preying upon them, (ii) the erosion base of axial and tributary rivers causing an increase in the availability of flint raw materials and (iii) conditions for loess accumulation in northern France and Belgium and the resulting preservation of Middle Palaeolithic sites