Audit of Oral Histopathology Service at a Nigerian Tertiary Institution over a 24-Year Period

No AbstractKEYWORDS: Oral, Biopsy, Histopathology Service, Nigeria

Clinico-pathological profile of head and neck malignancies at University College Hospital, Ibadan, Nigeria

<p>Abstract</p> <p>Introduction</p> <p>This retrospective study analysed head and neck malignancies seen over a 19-year period at the University College Hospital, Ibadan.</p> <p>Methodology</p> <p>One thousand, one hundred and ninety two patients with head and neck malignancies were analysed according to age, gender, topography and histology.</p> <p>Results</p> <p>There was an annual hospital frequency of 62 cases per year. The overall mean age for these malignancies was 43.9 (SD ± 19.3) years. The lesions from the respiratory tract were the most frequent (43.2%) of all cases. The palate was the most frequent intra-oral site (13.8%). Epithelial malignancies constituted 73.4% of all cases with a male: female ratio of 2:1, a mean age of 48.1 (SD ± 17.5) years and were mostly located in the larynx (19.7%). Lymphomas constituted 17.5% of all head and neck cancers with a male: female ratio of 1.6:1, a mean age of 35.1 (SD ± 20.6) years and nodal involvement (39.7%) was most common. Sarcomas constituted 8.9% of all malignancies with a male: female ratio of 1.5:1, mean age of 27.1 (SD ± 16.7) years and the maxillofacial bones (42.5%) were most commonly involved. Neuroendocrine malignancies accounted for 0.2% of head and neck malignancies with a male: female ratio of 1:1, a mean age of 28.5 (SD ± 6.4) years and both cases involved the nose.</p> <p>Conclusion</p> <p>This study has further confirmed that carcinomas remain the most frequent cancers of the head and neck region in south-western Nigeria.</p