A holistic approach to recycling of CRT glass and PCBs in Vietnam: Policy paper

Rapidly growing quantities of e-waste (WEEE) demand the increasing attention of environmental policy all over the world. Developing countries are particularly affected by recycling and disposal activities, which are deemed harmful to health and environment. Holistic or integrated approaches to WEEE policy are required. The paper discusses first recycling technologies for glass from cathode ray tubes (CRT) and printed circuit boards (PCBs) in Vietnam. Thereafter the German approach to WEEE policy is adjusted to allow for an integrated policy. This is then adapted to allow for the recycling of used monitors and computers.Sự gia tăng một cách nhanh chóng số lượng các chất thải từ các thiết bị điện, điện tử (WEEE) đòi hỏi sự tăng cường chú ý tới các chính sách môi trường toàn cầu. Các nước đang phát triển bị tác động đặc biệt bởi các hoạt động tái chế, do nó ảnh hưởng xấu tới sức khỏe và môi trường. Các phương pháp tổ hợp và toàn diện đối với các chính sách quản lý chất thải điện tử (WEEE) là đòi hỏi cấp thiết. Trong bài báo này, trước hết phân tích đánh giá các công nghệ tái chế thủy tinh đèn hình (thủy tinh CRT) và bản mạch in điện tử (PCBs) ở Việt Nam. Tiếp theo là phương pháp tiếp cận các chính sách quản lý chất thải điện tử của Cộng hòa liên bang Đức được sử dụng để điều chỉnh cho thích hợp nhằm đưa ra giải pháp tổ hợp có thể thích ứng cho việc tái chế màn hình Tivi và máy tính hỏng, hết hạn sử dụng và thải bỏ ở Việt Nam

A holistic approach to recycling of CRT glass and PCBs in Vietnam: Policy paper

Rapidly growing quantities of e-waste (WEEE) demand the increasing attention of environmental policy all over the world. Developing countries are particularly affected by recycling and disposal activities, which are deemed harmful to health and environment. Holistic or integrated approaches to WEEE policy are required. The paper discusses first recycling technologies for glass from cathode ray tubes (CRT) and printed circuit boards (PCBs) in Vietnam. Thereafter the German approach to WEEE policy is adjusted to allow for an integrated policy. This is then adapted to allow for the recycling of used monitors and computers.Sự gia tăng một cách nhanh chóng số lượng các chất thải từ các thiết bị điện, điện tử (WEEE) đòi hỏi sự tăng cường chú ý tới các chính sách môi trường toàn cầu. Các nước đang phát triển bị tác động đặc biệt bởi các hoạt động tái chế, do nó ảnh hưởng xấu tới sức khỏe và môi trường. Các phương pháp tổ hợp và toàn diện đối với các chính sách quản lý chất thải điện tử (WEEE) là đòi hỏi cấp thiết. Trong bài báo này, trước hết phân tích đánh giá các công nghệ tái chế thủy tinh đèn hình (thủy tinh CRT) và bản mạch in điện tử (PCBs) ở Việt Nam. Tiếp theo là phương pháp tiếp cận các chính sách quản lý chất thải điện tử của Cộng hòa liên bang Đức được sử dụng để điều chỉnh cho thích hợp nhằm đưa ra giải pháp tổ hợp có thể thích ứng cho việc tái chế màn hình Tivi và máy tính hỏng, hết hạn sử dụng và thải bỏ ở Việt Nam

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke

A holistic approach to recycling of CRT glass and PCBs in Vietnam: Policy paper

Rapidly growing quantities of e-waste (WEEE) demand the increasing attention of environmental policy all over the world. Developing countries are particularly affected by recycling and disposal activities, which are deemed harmful to health and environment. Holistic or integrated approaches to WEEE policy are required. The paper discusses first recycling technologies for glass from cathode ray tubes (CRT) and printed circuit boards (PCBs) in Vietnam. Thereafter the German approach to WEEE policy is adjusted to allow for an integrated policy. This is then adapted to allow for the recycling of used monitors and computers.Sự gia tăng một cách nhanh chóng số lượng các chất thải từ các thiết bị điện, điện tử (WEEE) đòi hỏi sự tăng cường chú ý tới các chính sách môi trường toàn cầu. Các nước đang phát triển bị tác động đặc biệt bởi các hoạt động tái chế, do nó ảnh hưởng xấu tới sức khỏe và môi trường. Các phương pháp tổ hợp và toàn diện đối với các chính sách quản lý chất thải điện tử (WEEE) là đòi hỏi cấp thiết. Trong bài báo này, trước hết phân tích đánh giá các công nghệ tái chế thủy tinh đèn hình (thủy tinh CRT) và bản mạch in điện tử (PCBs) ở Việt Nam. Tiếp theo là phương pháp tiếp cận các chính sách quản lý chất thải điện tử của Cộng hòa liên bang Đức được sử dụng để điều chỉnh cho thích hợp nhằm đưa ra giải pháp tổ hợp có thể thích ứng cho việc tái chế màn hình Tivi và máy tính hỏng, hết hạn sử dụng và thải bỏ ở Việt Nam

Investigation of Heavy Metal Effects on the Anaerobic Co-Digestion Process of Waste Activated Sludge and Septic Tank Sludge

The effect of copper, zinc, chromium, and lead on the anaerobic co-digestion of waste activated sludge and septic tank sludge in Hanoi was studied in the fermentation tests by investigating the substrate degradation, biogas production, and process stability at the mesophilic fermentation. The tested heavy metals were in a range of concentrations between 19 and 80 ppm. After the anaerobic tests, the TS, VS, and COD removal efficiency was 4.12%, 9.01%, and 23.78% for the Cu(II) added sample. Similarly, the efficiencies of the Zn(II) sample were 1.71%, 13.87%, and 16.1% and Cr(VI) efficiencies were 15.28%, 6.6%, and 18.65%, while the TS, VS, and COD removal efficiency of the Pb(II) added sample was recorded at 16.1%, 17.66%, and 16.03% at the concentration of 80 ppm, respectively. Therefore, the biogas yield also decreased by 36.33%, 31.64%, 31.64%, and 30.60% for Cu(II), Zn(II), Cr(VI), and Pb(II) at the concentration of 80 ppm, compared to the raw sample, respectively. These results indicated that Cu(II) had more inhibiting effect on the anaerobic digestion of the sludge mixture than Zn(II), Cr(VI), and Pb(II). The relative toxicity of these heavy metals to the co-digestion process was as follows: Cu (the most toxic) > Zn > Cr > Pb (the least toxic). The anaerobic co-digestion process was inhibited at high heavy metal concentration, which resulted in decreased removal of organic substances and produced biogas

A Fixed-Bed Column Study for Removal of Organic Dyes from Aqueous Solution by Pre-Treated Durian Peel Waste

A number of harmful effects on the ecosystem, the life of humankind, and living species caused by dye-contaminated wastewater have urged the development for an efficient and cost-efficient treatment method for colored effluents. The cellulose-based adsorbents have been considered as a facile and efficient approach to remove hazardous pollutants because of the abundance of inexpensive agricultural wastes in Viet Nam. This study aims to investigate the elimination of methylene blue (MB) and crystal violet (VL) from wastewater using a fixed-bed column of pre-treated durian peel. Examined variables in the process are bed depths (2–6 cm), flow rate (5–20 mL/min), and influent dye concentrations (200–600 mg/L). The highest adsorption amount of pre-treated DP was 235.80 mg/g and 527.64 mg/g, respectively, on a 600 mg/L of methylene blue and crystal violet achieved within a bed height of 4 cm and a flow rate of 10 mL/min. Accordingly, the breakthrough curves were constructed and modeled using the relevant theoretical models under the effects of different experimental conditions. Pre-treated durian peel was found to exhibit high adsorption capacity for cationic dye in an initial concentration of 200–600 mg/L with complete removal being obtained

Adopting construction 4.0 to promote sustainability in the Mekong Delta of Vietnam: a fuzzy delphi study

This study contributes to the understanding of Construction 4.0 (C4.0) adoption in developing countries, with a specific focus on the Mekong Delta region of Vietnam. Due to a lack of innovative methods in construction, developing nations struggle to promote sustainability. To cover this research gap, prior studies have addressed the critical success factors (CSFs) and motivations but neglected the complexity and interconnections of CSFs. This study proposes a Fuzzy Delphi – Analytic Hierarchy Process analysis to discern the most influential factors for successful C4.0 adoption. The results underscore that the motivation to reduce the use of natural resources and establish an effective logistics network supersedes cost-related considerations. Collaboration, information sharing, and strategic management emerge as pivotal CSFs. This study provides valuable insights for policymakers and practitioners aiming to promote sustainable construction practices through C4.0 technology in a developing context.</p

ZIKV Inhibitors Based on Pyrazolo[3,4‑d]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies

The Zika virus (ZIKV) is believed to cause birth defects, and no anti-ZIKV drugs have been approved by medical organizations to date. Starting from antimicrobial lead compounds with a pyrazolo[3,4-d]pyridazine-7-one scaffold, we synthesized 16 derivatives and screened their ability to interfere with ZIKV infection utilizing a cell-based phenotypic assay. Of these, five compounds showed significant inhibition of ZIKV with a selective index value greater than 4.6. In particular, compound 9b showed the best anti-ZIKV activity with a selectivity index of 22.4 (half-maximal effective concentration = 25.6 μM and 50% cytotoxic concentration = 572.4 μM). Through the brine shrimp lethality bioassay, 9b, 10b, 12, 17a, and 19a showed median lethal dose values in a range of 87.2-100.3 μg/mL. Compound 9b was also targeted to the NS2B-NS3 protease of ZIKV using molecular docking protocols, in which it acted as a noncompetitive inhibitor and strongly bound to five key amino acids (His51, Asp75, Ser135, Ala132, Tyr161). Utilizing the pharmacophore model of 9b, the top 20 hits were identified as prospective inhibitors of NS2B-NS3 protease, and six of them were confirmed for their stability with the protease via redocking and molecular dynamics simulations

Multiresidue Pesticides Analysis of Vegetables in Vietnam by Ultrahigh-Performance Liquid Chromatography in Combination with High-Resolution Mass Spectrometry (UPLC-Orbitrap MS)

An ultrahigh-performance liquid chromatography in combination with high-resolution mass spectrometry Thermo Q-Extractive Focus Orbitrap MS has been introduced for analysis of multiclass pesticides in vegetable samples collected in Hanoi, Vietnam. Multiclass pesticides were separated on the Thermo Hypersil Gold PFP column utilizing a gradient of the mobile phase consisting of 5 mM ammonium formate, 0.1% formic acid in deionized water, and methanol. The target analytes were detected in the full-scan mode on Thermo Scientific Q-Exactive Focus Orbitrap MS for quantitation at the optimum operating conditions. These conditions included, but not limit to, the resolution of 70000 at the full width at half maximum in both positive and negative mode, mass range from 80 to 1000 m/z, and optimized parameters for the heated electrospray ionization source. The identification of the analytes in real samples was based on retention times, mass to charge ratios, mass accuracies, and MS/MS spectra at the confirmation mode with the inclusion list of target analytes. The mass accuracies of target analytes were from −4.14 ppm (dinotefuran) to 1.42 ppm (cinosulfuron) in the neat solvent and from −3.91 ppm (spinosad D) to 1.29 ppm (cinosulfuron) in the matrix-matched solution. Target analytes in the vegetable-based matrix were extracted by the QuEChERS method. Some critical parameters of the analytical method such as linearity, repeatability, limit of detection, and limit of quantitation have been evaluated and implemented. Excellent LOD and LOQ of the developed method were achieved at the range of 0.04–0.85 and 0.13–2.9 μg·kg−1, respectively. Intraday and interday repeatability of the analytical signal (peak area, n=6) of the developed method were below 3% and 10%, correspondingly. The matrix effect, extraction recovery, and overall recovery were fully investigated by spiking experiments. Experimental results demonstrated that the ionization suppression or enhancement was the main contribution on the overall recoveries of target analytes. Finally, the in-house validated method was applied to pesticides screening in vegetables samples in local villages in Hanoi, Vietnam. The concentrations of all target analytes were below limit of quantitation and lower than US-FDA or EU maximum residue levels