Analysis of the SEA-OWC-Clam wave energy device part B:structural integrity analysis

In this paper the dynamic loads determined for the SEA-OWC-Clam wave energy device, treated as a floating offshore structure with six degrees-of-freedom with partial internal sealed-off channels, are applied to assess its structural integrity. This task necessitates the matching of the boundary element determined dynamic pressures to the corresponding Finite Element Analysis (FEA) to determine the effective von Mises stress levels. A decomposition of the total load to permit attribution to different aspects of radiation and diffraction loading is presented. Possible modification of structural details is identified by undertaking a more local stiffened plate analysis to improve structural detail

VALUTAZIONE DELLA RISPOSTA SISMICA DI EDIFICI ESISTENTI ALTI IN C.A. A PARETI SISMO-RESISTENTI. UN ESEMPIO: LA SEDE DELLA REGIONE EMILIA-ROMAGNA

In this work it was generally discussed the issue of the seismic behavior of buildings with resistant walls in reinforced concrete, in addition to the issue of the safety assessment of existing buildings , more and more major current topic in recent years. Specifically, are then shown the results obtained from the evaluation of seismic safety carried out on the headquarters of the Emilia-Romagna region, which is made with a seismic-resistant cylindrical walls in circular and semi-circular section. To perform this assessment of safety has also discussed the problem of the calculation of the shear strength in the walls with circular and semi-circular section making the point about the state of the art scientific research and proposing a simplified method of calculation of said shear resistance. Finally, we applied the method of "Direct Displacement Based Design" (D.D.B.D.) in the structure analyzed by checking if the application of this design method could provide more quickly a value for estimate the safety factor of the building

Fatigue assessment of a FSAE car rear upright by a closed form solution of the critical plane method

Material fatigue is extensively discussed and researched within scientific and industrial communities. Fatigue damage poses a significant challenge for both metallic and non-metallic components, often resulting in unexpected failures of in-service parts. Within multiaxial fatigue assessment, critical plane methods have gained importance due to their ability to characterize a component's critical location and detect early crack propagation. However, the conventional approach to calculate critical plane factors is time-consuming, making it primarily suitable for research purposes or when critical regions are already known. In many real-world scenarios, identifying the critical area of a component is difficult due to complex geometries, varying loads, or time limitations. This challenge becomes particularly crucial after topological optimization of components and in the context of lightweight design. Recently, the authors proposed an efficient method for evaluating critical plane factors in closed form, applicable to all cases that necessitate the maximization of specific parameters based on stress and strain components or their combination. This paper presents and validates the proposed methodology, with reference to a rear upright of a FSAE car, which is characterized by a complex geometry and is subjected to non-proportional loading conditions. The efficient algorithm demonstrated a substantial reduction in computation time compared to the standard plane scanning method, while maintaining solution accuracy

Comparative finite element modelling of aneurysm formation and physiologic inflation in the descending aorta

Despite the general interest in aneurysm rupture prediction, the aneurysm formation has received limited attention. The goal of this study is to assess whether an aneurysm may be instigated in a healthy model of an aorta inflated by a supra-physiological pressure. The effect of two main aspects on numerical predictions has been explored: i) the geometric design and ii) the constitutive law adopted to represent the material properties. Firstly, higher values of wall stress and displacement magnitude were generated in the physiologic model compared to the cylindrical one when assigning the same material properties. Secondly, greater deformations are observed in the anisotropic model compared to the isotropic one

A transverse isotropic viscoelastic constitutive model for aortic valve tissue

A new anisotropic viscoelastic model is developed for application to the aortic valve (AV). The directional dependency in the mechanical properties of the valve, arising from the predominantly circumferential alignment of collagen fibres, is accounted for in the form of transverse isotropy. The rate dependency of the valve's mechanical behaviour is considered to stem from the viscous (η) dissipative effects of the AV matrix, and is incorporated as an explicit function of the deformation rate (λ˙). Model (material) parameters were determined from uniaxial tensile deformation tests of porcine AV specimens at various deformation rates, by fitting the model to each experimental dataset. It is shown that the model provides an excellent fit to the experimental data across all different rates and satisfies the condition of strict local convexity. Based on the fitting results, a nonlinear relationship between η and λ˙ is established, highlighting a ‘shear-thinning’ behaviour for the AV with increase in the deformation rate. Using the model and these outcomes, the stress–deformation curves of the AV tissue under physiological deformation rates in both the circumferential and radial directions are predicted and presented. To verify the predictive capabilities of the model, the stress–deformation curves of AV specimens at an intermediate deformation rate were estimated and validated against the experimental data at that rate, showing an excellent agreement. While the model is primarily developed for application to the AV, it may be applied without the loss of generality to other collagenous soft tissues possessing a similar structure, with a single preferred direction of embedded collagen fibres

SARS-CoV-2 and Companion Animals: Sources of Information and Communication Campaign during the COVID-19 Pandemic in Italy

This study analyzed data on the sources and the level of Italians' awareness on the risk of infection by SARS-CoV-2 at the human-animal interface. Data were collected through a survey-type investigation on a representative sample of the Italian population. Forty-five percent of the interviewees were aware that companion animals could be infected by SARS-CoV-2. However, 29.8% were familiar with preventive measures to adopt to avoid viral transmission between infected humans and companion animals, and only 20.7% knew which companion animals could be at risk of infection. Higher awareness regarding the risk of SARS-CoV-2 transmission between animals and humans (51.7%) and the measures to prevent it (33.3%) was detected among companion animals' owners. Notably, 40.4% of interviewees were not informed at all. Television broadcasts (26.4%) represented the main source of information, while only 3.5% of the interviewees relied on veterinarians, of which 31.9% considered this source of information as the most trustworthy. Overall, 72.4% of Italians recognized that the communication campaign on COVID-19 and companion animals was inadequate. This survey highlights the need for increasing the public awareness of the risk of companion animals being infected with SARS-CoV-2 and the involvement of professionals in the public communication on zoonoses

Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy

AbstractThe possibility that some combinations of mtDNA polymorphisms, previously associated with Leber's hereditary optic neuropathy (LHON), may affect mitochondrial respiratory function was tested in osteosarcoma-derived transmitochondrial cytoplasmic hybrids (cybrids). In this cellular system, in the presence of the same nuclear background, different exogenous mtDNAs are used to repopulate a parental cell line previously devoid of its original mtDNA. No detectable differences in multiple parameters exploring respiratory function were observed when mtDNAs belonging to European haplogroups X, H, T and J were used. Different possible explanations for the previously established association between haplogroup J and LHON 11778/ND4 and 14484/ND6 pathogenic mutations are discussed, including the unconventional proposal that mtDNA haplogroup J may exert a protective rather than detrimental effect