71 research outputs found
Seismic Vulnerability Assessment of Priority Cultural Heritage Structures in the Philippines
At the end of 2013 two catastrophic events occurred in the Philippines: the M 7.2 earthquake
in Bohol and the strongest ever recorded Typhoon Haiyan, causing destruction across the islands of Cebu,
Bohol and the Visayas region. These events raised the need to carry out a multi-hazard risk assessment of
heritage buildings, many of which were irretrievably lost in the disasters. Philippines’ Department of
Tourism engaged ARS Progetti S.P.A., Rome, Italy, and the Center for Conservation of Cultural Property
and Environment in the Tropics (CCCPET), University of Sto. Tomas, Manila, to undertake the
“Assessment of the Multi-Hazard Vulnerability of Priority Cultural Heritage Structures in the
Philippines”, with experts from University College London, UK, and De La Salle University.
The main objective of the project was to reduce the vulnerability of cultural heritage structures to multiple
natural hazards, including earthquake, typhoon, flood, by: (i) prioritizing of specific structures based on
hazard maps and historical records; (ii) assessing their vulnerability; and (iii) recommending options to
mitigate the impacts on them. The paper presents the methodology introduced to determine the seismic
risk these heritage buildings are exposed to. All the selected cultural heritage structures are under the
jurisdiction of the National Museum Commission of Philippines and of the National Commission for
Culture and Arts
Tailoring 3D single-walled carbon nanotubes anchored to indium tin oxide for natural cellular uptake and intracellular sensing.
The ability to monitor intracellular events in real time is paramount to advancing fundamental biological and clinical science. We present the first demonstration of a direct interface of vertically aligned single-walled carbon nanotubes (VASWCNTs) with eukaryotic cells, RAW 264.7 mouse macrophage cell line. The cells were cultured on indium tin oxide with VASWCNTs. VASWCNTs entered the cells naturally without application of any external force and were shown to sense the intracellular presence of a redox active moiety, methylene blue. The technology developed provides an alluring platform to enable electrochemical study of an intracellular environment
Choice of boundary condition for lattice-Boltzmann simulation of moderate-Reynolds-number flow in complex domains
Modeling blood flow in larger vessels using lattice-Boltzmann methods comes
with a challenging set of constraints: a complex geometry with walls and
inlet/outlets at arbitrary orientations with respect to the lattice,
intermediate Reynolds number, and unsteady flow. Simple bounce-back is one of
the most commonly used, simplest, and most computationally efficient boundary
conditions, but many others have been proposed. We implement three other
methods applicable to complex geometries (Guo, Zheng and Shi, Phys Fluids
(2002); Bouzdi, Firdaouss and Lallemand, Phys. Fluids (2001); Junk and Yang
Phys. Rev. E (2005)) in our open-source application \HemeLB{}. We use these to
simulate Poiseuille and Womersley flows in a cylindrical pipe with an arbitrary
orientation at physiologically relevant Reynolds (1--300) and Womersley (4--12)
numbers and steady flow in a curved pipe at relevant Dean number (100--200) and
compare the accuracy to analytical solutions. We find that both the
Bouzidi-Firdaouss-Lallemand and Guo-Zheng-Shi methods give second-order
convergence in space while simple bounce-back degrades to first order. The BFL
method appears to perform better than GZS in unsteady flows and is
significantly less computationally expensive. The Junk-Yang method shows poor
stability at larger Reynolds number and so cannot be recommended here. The
choice of collision operator (lattice Bhatnagar-Gross-Krook vs.\ multiple
relaxation time) and velocity set (D3Q15 vs.\ D3Q19 vs.\ D3Q27) does not
significantly affect the accuracy in the problems studied.Comment: Submitted to Phys. Rev. E, 14 pages, 6 figures, 5 table
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