202 research outputs found

    Parkinson's Disease in Practice (2nd edition)

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    Clinical Hypertension in Practice (2nd edition)

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    Aerobic, resistance, and mind-body exercise are equivalent to mitigate symptoms of depression in older adults: A systematic review and network meta-analysis of randomised controlled trials

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    Background: Exercise has been identified as an allied health strategy that can support the management of depression in older adults, yet the relative effectiveness for different exercise modalities is unknown. To meet this gap in knowledge, we present a systematic review and network meta-analysis of randomised controlled trials (RCTs) to examine the head-to-head effectiveness of aerobic, resistance, and mind-body exercise to mitigate depressive symptoms in adults aged ≄ 65 years. Methods: A PRISMA-NMA compliant review was undertaken on RCTs from inception to September 12 th, 2019. PubMed, Web of Science, CINAHL, Health Source: Nursing/Academic Edition, PsycARTICLES, PsycINFO, and SPORTDiscus were systematically searched for eligible RCTs enrolling adults with a mean age ≄ 65 years, comparing one or more exercise intervention arms, and which used valid measures of depressive symptomology. Comparative effectiveness was evaluated using network meta-analysis to combine direct and indirect evidence, controlling for inherent variation in trial control groups. Results: The systematic review included 81 RCTs, with 69 meeting eligibility for the network meta-analysis ( n = 5,379 participants). Pooled analysis found each exercise type to be effective compared with controls (Hedges' g = -0.27 to -0.51). Relative head-to-head comparisons were statistically comparable between exercise types: resistance versus aerobic (Hedges' g = -0.06, PrI = -0.91, 0.79), mind-body versus aerobic (Hedges' g = -0.12, PrI = -0.95, 0.72), mind-body versus resistance (Hedges' g = -0.06, PrI = -0.90, 0.79). High levels of compliance were demonstrated for each exercise treatment. Conclusions: Aerobic, resistance, and mind-body exercise demonstrate equivalence to mitigate symptoms of depression in older adults aged ≄ 65 years, with comparably encouraging levels of compliance to exercise treatment. These findings coalesce with previous findings in clinically depressed older adults to encourage personal preference when prescribing exercise for depressive symptoms in older adults, irrespective of severity. Registration: PROSPERO CRD42018115866 (23/11/2018). © 2020 Miller KJ et al

    Team performance indicators which differentiate between winning and losing in elite Gaelic football

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    The objective of this study was to identify performance indicators which differentiated between winning and losing elite Gaelic football teams. Eighty three technical and tactical performance variables were measured in 13 teams during 26 league and championship games throughout 2014-15. Univariate analysis of full-games revealed that winners achieved a significantly higher total score, number of scores, shots, points, points from play and goals, resulting in superior shot efficiency, average attack per score, and scores per 10 possessions. Winners gained significantly more turnovers and completed significantly less unsuccessful hand passes. Winners also performed significantly less kick outs, resulting in fewer successful kick outs and successful dead ball kick passes overall. A principal component analysis, conducted on 18 variables produced 4 components, which explained 81.9% of the variance. Both logistic regression (8.00, χ 2 (1) = 16.00, p < 0.001) and discriminant analysis (Ʌ = 0.53, χ 2 (1) = 13.77, p < 0.001) revealed that 1 component; defensive counterattacking, significantly contributed to outcome and differentiated winners from losers with a cross-validation accuracy of 87.5%. Coaches can use this information to organise their defensive system to generate opposition turnovers and also incorporate sufficient flexibility to facilitate effective transitions to exploit their own offensive counterattacking opportunities

    Alterations in Team Physical Performance and Possession in Elite Gaelic Football Competition

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    Differences in performance between winning and losing were examined in 1 elite Gaelic football team in 20 games across 2 complete competitive seasons. Possession was codified using Dartfish TeamPro software and distance covered; walking, jogging, running, and running at high and maximum speeds, was evaluated using Catapult Optimeye S5 player tracking devices. Distance covered in low intensity activity (LIA, ˂4.0 m.s-1 ), high intensity running (HIR, ≄4.0 m·s-1 ) and very high intensity running (VHIR, ≄5.5 m·s-1 ) was also examined along with PlayerLoadℱ, which represented a composite of all accelerations. Data from 53 players (n=405 files) was collated into specific match periods to facilitate a temporal analysis between the first and second halves and from quarter 1 (Q1) to quarter 4 (Q4), with significance accepted at p ≀ 0.05. Total distance and running was higher in games lost, whereas total distance, walking and LIA was higher in halves lost. Only walking was higher in quarters lost. The percentage of possession declined in halves and quarters lost. In games lost, high speed running declined in the second half. From Q1 to Q4; PlayerLoadℱ, total distance, jogging, high speed running, HIR and VHIR, decreased in all games combined and in games lost. Possession frequency declined in Q4 in all games and in games won. Overall, total distance was higher in games lost and physical performance declines were more pronounced when examined by match quarter compared to half and were only apparent in games lost. Similarly, reductions in possession frequency and percentage were more evident when examined by quarter or period lost, respectively. These findings can inform the prescription of conditioning and field-training strategies to mitigate the reductions in performance observed in losing and towards the end of games

    Evaluation Report, Holiday Activities & Food Programme for Northamptonshire Sport, Full Report

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    According to the Department for Education, there are 1.63 million children eligible for Free School Meals (FSM). Within Northamptonshire there are 184,308 children and young people, aged 0-19 years old, of which 14% are eligible for FSM. As FSM eligibility is a proxy for socioeconomic disadvantage, these statistics highlight that a significant proportion of children in Northamptonshire are from disadvantaged backgrounds. Due to increased costs and reduced income, children and young people from disadvantaged backgrounds are more likely to experience a gap in learning and have ‘unhealthy holidays’ during the school holiday period. To bridge this ‘gap’, the Holiday Activities and Food (HAF) Programme was created by central Government. This report evaluates the HAF Programme that was delivered in Northamptonshire during the June to August 2021 Summer Holidays. 2,490 children and young people attended the HAF Programme (15.12% of FSM eligible children), from areas across Northamptonshire, with a catchment area of approximately 2,335 km2 and 215 schools

    Association between community-based self-reported COVID-19 symptoms and social deprivation explored using symptom tracker apps: A repeated cross-sectional study in Northern Ireland

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    Objectives: The aim of the study was to investigate the spatial and temporal relationships between the prevalence of COVID-19 symptoms in the community-level and area-level social deprivation. Design: Spatial mapping, generalised linear models, using time as a factor and spatial-lag models were used to explore the relationship between self-reported COVID-19 symptom prevalence as recorded through two smartphone symptom tracker apps and a range of socioeconomic factors using a repeated cross-sectional study design. Setting: In the community in Northern Ireland, UK. The analysis period included the earliest stages of non-pharmaceutical interventions and societal restrictions or \u27lockdown\u27 in 2020. Participants: Users of two smartphone symptom tracker apps recording self-reported health information who recorded their location as Northern Ireland, UK. Primary outcome measures: Population standardised self-reported COVID-19 symptoms and correlation between population standardised self-reported COVID-19 symptoms and area-level characteristics from measures of multiple deprivation including employment levels and population housing density, derived as the mean number of residents per household for each census super output area. Results: Higher self-reported prevalence of COVID-19 symptoms was associated with the most deprived areas (p \u3c 0.001) and with those areas with the lowest employment levels (p \u3c 0.001). Higher rates of self-reported COVID-19 symptoms within the age groups, 18-24 and 25-34 years were found within the most deprived areas during the earliest stages of non-pharmaceutical interventions and societal restrictions (\u27lockdown\u27). Conclusions: Through spatial regression of self-reporting COVID-19 smartphone data in the community, this research shows how a lens of social deprivation can deepen our understanding of COVID-19 transmission and prevention. Our findings indicate that social inequality, as measured by area-level deprivation, is associated with disparities in potential COVID-19 infection, with higher prevalence of self-reported COVID-19 symptoms in urban areas associated with area-level social deprivation, housing density and age

    Risk of COVID-19 death in adults who received booster COVID-19 vaccinations in England

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    The emergence of the COVID-19 vaccination has been critical in changing the course of the COVID-19 pandemic. To ensure protection remains high in vulnerable groups booster vaccinations in the UK have been targeted based on age and clinical vulnerabilities. We undertook a national retrospective cohort study using data from the 2021 Census linked to electronic health records. We fitted cause-specific Cox models to examine the association between health conditions and the risk of COVID-19 death and all-other-cause death for adults aged 50-100-years in England vaccinated with a booster in autumn 2022. Here we show, having learning disabilities or Down Syndrome (hazard ratio=5.07;95% confidence interval=3.69-6.98), pulmonary hypertension or fibrosis (2.88;2.43-3.40), motor neuron disease, multiple sclerosis, myasthenia or Huntington’s disease (2.94, 1.82-4.74), cancer of blood and bone marrow (3.11;2.72-3.56), Parkinson’s disease (2.74;2.34-3.20), lung or oral cancer (2.57;2.04 to 3.24), dementia (2.64;2.46 to 2.83) or liver cirrhosis (2.65;1.95 to 3.59) was associated with an increased risk of COVID-19 death. Individuals with cancer of the blood or bone marrow, chronic kidney disease, cystic fibrosis, pulmonary hypotension or fibrosis, or rheumatoid arthritis or systemic lupus erythematosus had a significantly higher risk of COVID-19 death relative to other causes of death compared with individuals who did not have diagnoses. Policy makers should continue to priorities vulnerable groups for subsequent COVID-19 booster doses to minimise the risk of COVID-19 death
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