8 research outputs found
Recommended from our members
A Glossary of Selected Telecommunications Terms
The following glossary provides short definitions and descriptions of
selected telecommunications terminology, agencies, and organizations, as well as a listing of key laws and Federal Communications Commission regulations and decisions
Recommended from our members
Internet: An Overview of Six Key Policy Issues Affecting Its Use and Growth
Report to Congress on the internet in the closing years of the twentieth century, including discussions on encryption, security, privacy, computer fraud, and more
Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host
The cellular adaptive immune response plays a key role in resolving influenza
infection. Experiments where individuals are successively infected with
different strains within a short timeframe provide insight into the underlying
viral dynamics and the role of a cross-reactive immune response in resolving an
acute infection. We construct a mathematical model of within-host influenza
viral dynamics including three possible factors which determine the strength of
the cross-reactive cellular adaptive immune response: the initial naive T cell
number, the avidity of the interaction between T cells and the epitopes
presented by infected cells, and the epitope abundance per infected cell. Our
model explains the experimentally observed shortening of a second infection
when cross-reactivity is present, and shows that memory in the cellular
adaptive immune response is necessary to protect against a second infection.Comment: 35 pages, 12 figure
Recommended from our members
Internet: An Overview of Six Key Policy Issues Affecting Its Use and Growth
Report to Congress on the internet in the closing years of the twentieth century, including discussions on encryption, security, privacy, computer fraud, and more