Unsupervised spectral classification of astronomical x-ray sources based on independent component analysis

By virtue of the sensitivity of the XMM-Newton and Chandra X-ray telescopes, astronomers are capable of probing increasingly faint X-ray sources in the universe. On the other hand, we have to face a tremendous amount of X-ray imaging data collected by these observatories. We developed an efficient framework to classify astronomical X-ray sources through natural grouping of their reduced dimensionality profiles, which can faithfully represent the high dimensional spectral information. X-ray imaging spectral extraction techniques, which use standard astronomical software (e.g., SAS, FTOOLS and CIAO), provide an efficient means to investigate multiple X-ray sources in one or more observations at the same time. After applying independent component analysis (ICA), the high-dimensional spectra can be expressed by reduced dimensionality profiles in an independent space. An infrared spectral data set obtained for the stars in the Large Magellanic Cloud,observed by the Spitzer Space Telescope Infrared Spectrograph, has been used to test the unsupervised classification algorithms. The least classification error is achieved by the hierarchical clustering algorithm with the average linkage of the data, in which each spectrum is scaled by its maximum amplitude. Then we applied a similar hierarchical clustering algorithm based on ICA to a deep XMM-Newton X-ray observation of the field of the eruptive young star V1647 Ori. Our classification method establishes that V1647 Ori is a spectrally distinct X-ray source in this field. Finally, we classified the Xray sources in the central field of a large survey, the Subaru/XMM-Newton deep survey, which contains a large population of high-redshift extragalactic sources. A small group of sources with maximum spectral peak above 1 keV are easily picked out from the spectral data set, and these sources appear to be associated with active galaxies. In general, these experiments confirm that our classification framework is an efficient X-ray imaging spectral analysis tool that gives astronomers insight into the fundamental physicalmechanisms responsible for X-ray emission and, furthermore, can be applied to a wide range of the electromagnetic spectrum

Gap Structure of the Overdoped Iron-Pnictide Superconductor Ba(Fe0.942_{0.942}Ni0.058_{0.058})2_{2}As2_{2}: A Low-Temperature Specific-Heat Study

Low-temperature specific heat (SH) is measured on the postannealed Ba(Fe_{1-x}Ni_x)_2As_2 single crystal with x = 0.058 under different magnetic fields. The sample locates on the overdoped sides and the critical transition temperature is determined to be 14.8 K by both the magnetization and SH measurements. A simple and reliable analysis shows that, besides the phonon and normal electronic contributions, a clear T2 termemerges in the low temperature SH data.Our observation is similar to that observed in the Co-doped system in our previous work and is consistent with the theoretical prediction for a superconductor with line nodes in the energy gap.Comment: 5 pages, 4 figure

The expression and antigenicity of a truncated spike-nucleocapsid fusion protein of severe acute respiratory syndrome-associated coronavirus

<p>Abstract</p> <p>Background</p> <p>In the absence of effective drugs, controlling SARS relies on the rapid identification of cases and appropriate management of the close contacts, or effective vaccines for SARS. Therefore, developing specific and sensitive laboratory tests for SARS as well as effective vaccines are necessary for national authorities.</p> <p>Results</p> <p>Genes encoding truncated nucleocapsid (N) and spike (S) proteins of <it>SARSCoV </it>were cloned into the expression vector <it>pQE30 </it>and fusionally expressed in <it>Escherichia coli </it>M15. The fusion protein was analyzed for reactivity with SARS patients' sera and with anti-sera against the two human coronaviruses <it>HCoV </it>229E and <it>HCoV </it>OC43 by ELISA, IFA and immunoblot assays. Furthermore, to evaluate the antigen-specific humoral antibody and T-cell responses in mice, the fusion protein was injected into 6-week-old BALB/c mice and a neutralization test as well as a T-cell analysis was performed. To evaluate the antiviral efficacy of immunization, BALB/c mice were challenged intranasally with <it>SARSCoV </it>at day 33 post injection and viral loads were determined by fluorescent quantitative RT-PCR. Serological results showed that the diagnostic sensitivity and specificity of the truncated S-N fusion protein derived the SARS virus were > 99% (457/460) and 100.00% (650/650), respectively. Furthermore there was no cross-reactivity with other two human coronaviruses. High titers of antibodies to <it>SRASCoV </it>appeared in the immunized mice and the neutralization test showed that antibodies to the fusion protein could inhibit <it>SARSCoV</it>. The T cell proliferation showed that the fusion protein could induce an antigen-specific T-cell response. Fluorescent quantitative RT-PCR showed that BALB/c mice challenged intranasally with <it>SARSCoV </it>at day 33 post injection were completely protected from virus replication.</p> <p>Conclusion</p> <p>The truncated S-N fusion protein is a suitable immunodiagnostic antigen and vaccine candidate.</p

[(E)-10-(2,6-Dimethyl­phenyl­imino)-9-methyl-9,10-dihydro­phenanthren-9-olato]penta­methyl­dialuminum(III)

The two Al atoms in the title compound, [Al2(CH3)5(C23H20NO)], are four-coordinated in a distorted tetra­hedral environment. The coordination of one Al atom includes three methyl-C atoms and the O atom from the ligand, whereas the second Al atom is surrounded by the O atom and one N atom from the ligand as well as by two methyl-C atoms. In the ligand, the dihedral angle between the two phenyl rings in the 9,10-dihydro­phenanthren unit is 20.64 (12)°