4,117 research outputs found

    Exact solution of the Zeeman effect in single-electron systems

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    Contrary to popular belief, the Zeeman effect can be treated exactly in single-electron systems, for arbitrary magnetic field strengths, as long as the term quadratic in the magnetic field can be ignored. These formulas were actually derived already around 1927 by Darwin, using the classical picture of angular momentum, and presented in their proper quantum-mechanical form in 1933 by Bethe, although without any proof. The expressions have since been more or less lost from the literature; instead, the conventional treatment nowadays is to present only the approximations for weak and strong fields, respectively. However, in fusion research and other plasma physics applications, the magnetic fields applied to control the shape and position of the plasma span the entire region from weak to strong fields, and there is a need for a unified treatment. In this paper we present the detailed quantum-mechanical derivation of the exact eigenenergies and eigenstates of hydrogen-like atoms and ions in a static magnetic field. Notably, these formulas are not much more complicated than the better-known approximations. Moreover, the derivation allows the value of the electron spin gyromagnetic ratio gsg_s to be different from 2. For completeness, we then review the details of dipole transitions between two hydrogenic levels, and calculate the corresponding Zeeman spectrum. The various approximations made in the derivation are also discussed in details.Comment: 18 pages, 4 figures. Submitted to Physica Script

    Severe Hypertriglyceridaemia as a result of Familial Chylomicronaemia:

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    Lipoprotein lipase deficiency causes severe hypertriglyceridaemia due to chylomicronaemia, and leads to recurrent and potentially life-threatening pancreatitis. This disorder can only be managed by dietary fat restriction as drugs are ineffective. We review the experience with familial chylomicronaemia in patients who attended the lipid clinics at Groote Schuur Hospital and Red Cross Children's War Memorial Hospital in Cape Town. Criteria for inclusion were an initial plasma triglyceride concentration of >15 mmol/l and a typical type I Fredrickson hyperlipidaemia pattern on plasma lipoprotein electrophoresis. A total of 29 patients were seen over 25 years. The mean age of presentation was 10 years, but ranged from 0 to 43 years. The modes of presentation differed: pancreatitis (N=16), eruptive xanthomata (N=2), coincidental detection of hypertriglyceridaemia (N=2), screening relatives (N=7), and after death from pancreatitis (N=1). Plasma triglycerides responded rapidly and dramatically to dietary fat restriction, and some patients sustained good control of the hyperlipidaemia. The onset of pancreatitis was earlier in patients of Indian ancestry, suggesting a genotype/phenotype interaction within this disorder. Genetic work-up indicated founder effects in the Afrikaner and Indian patients. Lipaemic plasma should be taken seriously at all ages, and necessitates work-up at specialised clinics where the diagnosis of chylomicronaemia or type I hyperlipidaemia facilitates appropriate dietary management that can prevent pancreatitis. South African Medical Journal Vol. 98 (2) 2008: pp. 105-10

    On the Nature of MeV-blazars

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    Broad-band spectra of the FSRQ (flat-spectrum-radio quasars) detected in the high energy gamma-ray band imply that there may be two types of such objects: those with steep gamma-ray spectra, hereafter called MeV-blazars, and those with flat gamma-ray spectra, GeV-blazars. We demonstrate that this difference can be explained in the context of the ERC (external-radiation-Compton) model using the same electron injection function. A satisfactory unification is reachable, provided that: (a) spectra of GeV-blazars are produced by internal shocks formed at the distances where cooling of relativistic electrons in a jet is dominated by Comptonization of broad emission lines, whereas spectra of MeV-blazars are produced at the distances where cooling of relativistic electrons is dominated by Comptonization of near-IR radiation from hot dust; (b) electrons are accelerated via a two step process and their injection function takes the form of a double power-law, with the break corresponding to the threshold energy for the diffusive shock acceleration. Direct predictions of our model are that, on average, variability time scales of the MeV-blazars should be longer than variability time scales of the GeV-blazars, and that both types of the blazar phenomenon can appear in the same object.Comment: Accepted for publication in the Astrophysical Journa

    Severe hypertriglyceridaemia as a result of familial chylomicronaemia:The Cape Town experience

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    Lipoprotein lipase deficiency causes severe hypertriglyceridaemia due to chylomicronaemia, and leads to recurrent and potentially life-threatening pancreatitis. This disorder can only be managed by dietary fat restriction as drugs are ineffective. We review the experience with familial chylomicronaemia in patients who attended the lipid clinics at Groote Schuur Hospital and Red Cross Children's War Memorial Hospital in Cape Town. Criteria for inclusion were an initial plasma triglyceride concentration of >15 mmol/l and a typical type I Fredrickson hyperlipidaemia pattern on plasma lipoprotein electrophoresis. A total of 29 patients were seen over 25 years. The mean age of presentation was 10 years, but ranged from 0 to 43 years. The modes of presentation differed: pancreatitis (N=16), eruptive xanthomata (N=2), coincidental detection of hypertriglyceridaemia (N=2), screening relatives (N=7), and after death from pancreatitis (N=1). Plasma triglycerides responded rapidly and dramatically to dietary fat restriction, and some patients sustained good control of the hyperlipidaemia. The onset of pancreatitis was earlier in patients of Indian ancestry, suggesting a genotype/phenotype interaction within this disorder. Genetic work-up indicated founder effects in the Afrikaner and Indian patients. Lipaemic plasma should be taken seriously at all ages, and necessitates work-up at specialised clinics where the diagnosis of chylomicronaemia or type I hyperlipidaemia facilitates appropriate dietary management that can prevent pancreatitis

    On Perception and Consciousness in HPPD:A Systematic Review

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    Hallucinogen-persisting perception disorder (HPPD) features as a diagnostic category in the DSM-5, ICD-11, and other major classifications, but our knowledge of the phenomenology of the perceptual symptoms involved and the changes in consciousness during the characteristic “flashbacks” is limited. We systematically evaluated original case reports and case series on HPPD to define its phenomenology, associated (psycho)pathology, and course. Our search of PubMed and Embase yielded 66 relevant publications that described 97 people who, together, experienced 64 unique symptoms of HPPD. Of these, 76% concerned symptoms characteristic of Alice in Wonderland syndrome, over 50% non-visual symptoms, and 38% perceptual symptoms not clearly linked to prior intoxication states. This is in contrast with the DSM-5 diagnostic criteria for HPPD. Even though less than half of the patients showed a protracted disease course of over a year, a third achieved remission. However, in patients with co-occurring depression (with or without anxiety) HPPD symptoms persisted longer and treatment outcomes were more often negative. Thus, unlike the acute stages of psychedelic drug intoxication, which may be accompanied by altered states of consciousness, HPPD is rather characterized by changes in the content of consciousness and an attentional shift from exogenous to endogenous phenomena. Since HPPD is a more encompassing nosological entity than suggested in the DSM-5, we recommend expanding its diagnostic criteria. In addition, we make recommendations for clinical practice and future research

    Emotional, Behavioral, and Physical Health Consequences in Caregivers of Children with Cancer: A Network Analysis Differentiation in Mothers’ and Fathers’ Reactivity

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    Background: Pediatric cancer presents mental and physical challenges for patients and their caregivers. However, parental distress has been understudied despite its negative impact on quality of life, disability, and somatic disorders. Parents of oncopediatric patients experience high levels of suffering with their resilience tested throughout their children’s illness. Identifying at-risk parents and offering specific treatments is crucial and urgent to prevent or alleviate negative outcomes. Methods: This study used statistical and network analyses to examine symptom patterns assessed by the Kellner Symptom Questionnaire in 16 fathers and 23 mothers at different time points: diagnosis, treatment, and discharge. Results: The results indicated significantly higher distress levels in parents of oncopediatric children compared to the control reference population. Gender-specific differences in symptom profiles were observed at each time point, and symptoms showed a gradual but non-significant decrease over time. Conclusions: The network analysis yielded valuable insights that, when applied in clinical practice, can guide the implementation of timely treatments to prevent and manage parental distress, thus addressing long-term, stress-related issues in primary caregivers of children diagnosed and treated for cancer

    The Diffuse Gamma-Ray Background from Supernovae

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    The Cosmic Gamma-ray Background (CGB) in the MeV region is believed to be due to photons from radioactivity produced in SNe throughout the history of galaxies in the universe. In particular, gamma-ray line emission from the decay chain 56Ni-> 56Co->56Fe provides the dominant photon source. Although iron synthesis occurs in all types of SNe, the contribution to the CGB is dominated by SNIa events due to their higher photon escape probabilities. Estimates of the star formation history in the universe suggest a rapid increase by a factor \~ 10 from the present to a redshift z_p ~ 1.5, beyond which it either remains constant or decreases slowly. We integrate the observed star formation history to determine the CGB from the corresponding SN rate history. In addition to gamma-rays from short-lived radioactivity in SNIa and SNII/Ibc we also calculate the minor contributions from long-lived radioactivities (26Al, 44Ti, 60Co, and electron-positron pair annihilation). Although progenitor evolution for SNIa is not yet fully understood, various arguments suggest delays of order 1-2 Gy between star formation and the production of SNIa's. The effect of this delay on the CGB is discussed. We emphasize the value of gamma-ray observations of the CGB in the MeV range as an independent tool for studies of the cosmic star formation history. If the delay between star formation and SNIa activity exceeds 1 Gy substantially, and/or the peak of the cosmic star formation rate occurs at a redshift much larger than unity, the gamma-ray production of SNIa would be insufficient to explain the observed CGB. Alternatively, the cosmic star formation rate would have to be higher (by a factor 2-3) than commonly assumed, which is in accord with several upward revisions reported in the recent literature.Comment: Minor changes, 26 pages, 9 figures, Accepted by Ap

    Musical hallucinations and their relation with epilepsy

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    Musical hallucinations are poorly understood phenomena. Their relation with epilepsy was first described over a century ago, but never systematically explored. We, therefore, reviewed the literature, and assessed all descriptions of musical hallucinations attributed to epileptic activity. Our search yielded 191 articles, which together describe 983 unique patients, with 24 detailed descriptions of musical hallucinations related to epilepsy. We also describe six of our own patients. Based on the phenomenological descriptions and neurophysiological data, we distinguish four subgroups of epilepsy-related musical hallucination, comprising auras/ictal, inter-ictal and post-ictal phenomena, and phenomena related to brain stimulation. The case descriptions suggest that musical hallucinations in epilepsy can be conceptualised as lying on a continuum with other auditory hallucinations, including verbal auditory hallucinations, and—notably—tinnitus. To account for the underlying mechanism we propose a Bayesian model involving top-down and bottom-up prediction errors within the auditory network that incorporates findings from EEG and MEG studies. An analysis of phenomenological characteristics, pharmacological triggers, and treatment effects suggests wider ramifications for understanding musical hallucinations. We, therefore, conclude that musical hallucinations in epilepsy open a window to understanding these phenomena in a variety of conditions.Stress and Psychopatholog

    Lithologic discrimination and alteration mapping from AVIRIS Data, Socorro, New Mexico

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    Geologic maps are, by their very nature, interpretive documents. In contrasts, images prepared from AVIRIS data can be used as uninterpreted, and thus unbiased, geologic maps. We are having significant success applying AVIRIS data in this non-quantitative manner to geologic problems. Much of our success has come from the power of the Linked Windows Interactive Data System. LinkWinds is a visual data analysis and exploration system under development at JPL which is designed to rapidly and interactively investigate large multivariate data sets. In this paper, we present information on the analysis technique, and preliminary results from research on potassium metasomatism, a distinctive and structurally significant type of alteration associated with crustal extension
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