26 research outputs found
Body measurements, blood biochemistry and blood pressure measurements in offspring by parental group.
<p>Box-and-whiskers plots show median and IQR (‘<b>+’</b> within the box denotes mean value) for the OMD (white boxes), OFD (hatched boxes) and ONoPD (grey boxes) in males (left) and females (right); box-and whiskers for rest of cohort (RoC, i.e. all those without diabetes excluded from the F<sub>1</sub>-offspring groups, [black boxes] for males and females) are also shown for comparison. Graphs are shown for Waist (A), HDL-cholesterol (B), Glucose (C), Systolic-blood pressure (D), Diastolic-blood pressure (E), BMI (F) and Percent body-fat (G). Groups were compared by Kruskal-Wallis, with level of significance between the groups indicated (* P<0.05, **P<0.01, *** P<0.001, **** P<0.0001).</p
The effect of comorbidity on the occurrence of depression and/or angina in GS:SFHS overall.
<p>The effect of comorbidity on the occurrence of depression and/or angina in GS:SFHS overall.</p
Model comparison between the full saturated, the full ACE Cholesky, and the full ADE Cholesky models for chronic pain<sup>±</sup> and cardiovascular disease (n = 2,902): Twins UK.
<p>Model comparison between the full saturated, the full ACE Cholesky, and the full ADE Cholesky models for chronic pain<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170653#t008fn002" target="_blank"><sup>±</sup></a> and cardiovascular disease (n = 2,902): Twins UK.</p
Co-occurrence of chronic pain, major depressive disorder and/or angina in GS:SFHS overall.
<p>Co-occurrence of chronic pain, major depressive disorder and/or angina in GS:SFHS overall.</p
Phenotypic correlations (r) with [95% confidence intervals] between observed variables in TwinsUK (n = 2,902).
<p>Phenotypic correlations (r) with [95% confidence intervals] between observed variables in TwinsUK (n = 2,902).</p
Path diagram of the Cholesky model for the covariance between chronic widespread pain (CWP) and cardiovascular disease (CVD) with adjustment for age.
<p>Path diagram of the Cholesky model for the covariance between chronic widespread pain (CWP) and cardiovascular disease (CVD) with adjustment for age.</p
Study characteristics of the n = 2,902 twins from the TwinsUK cohort.
<p>Study characteristics of the n = 2,902 twins from the TwinsUK cohort.</p
Characteristics of the overall GS:SFHS, unrelated subset and sibling pairs subset<sup>‡</sup>.
<p>Characteristics of the overall GS:SFHS, unrelated subset and sibling pairs subset<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170653#t001fn001" target="_blank"><sup>‡</sup></a>.</p
Phenotypic correlations of MDD status (absent = 0, affected = 1) between kinship dyads.
<p>Estimates from 500 jack-knifed replicates that sampled a single pair from each family for full siblings (N families with one or more pairs = 4306), full sisters (N = 2239), full brothers (N = 1161), opposite sex full-siblings (N = 2426), parent-child (N = 3402), grandparent-grandchild (N = 391), avuncular (aunt/uncle-niece/nephew N = 1826), first cousins (N = 1194).</p