674 research outputs found
UnerwĂŒnschte Arzneimittelreaktionen an der Haut: Zwischen trivial und fatal
Zusammenfassung: UnerwĂŒnschte Arzneimittelwirkungen stellen ein hĂ€ufiges medizinisches Problem dar. Insbesondere die Ăberempfindlichkeitsreaktionen sind wegen ihrer dosisunabhĂ€ngigen, nicht vorhersehbaren Natur hĂ€ufig beeindruckend und verunsichernd. Die klinischen Manifestationen an der Haut sind vielfĂ€ltig und reichen von makulösen Exanthemen ĂŒber bullöse Reaktionen zu Urtikaria und Angioödem bis hin zur Anaphylaxie. Aber auch systemische HypersensitivitĂ€tsreaktionen unter Einbeziehung fast aller Organsysteme kommen vor. Charakteristische klinische Alarmzeichen fĂŒr schwere allergische Arzneimittelreaktionen sowohl vom Sofort- als auch vom verzögerten Typ helfen, die Entwicklung einer allergischen Reaktion auf Arzneimittel frĂŒhzeitig zu diagnostizieren, die Zufuhr der potenziellen Allergene zu stoppen und therapeutische MaĂnahmen einzuleiten. Entscheidend fĂŒr die Aufarbeitung solcher Reaktionen im allergologisch-pharmakologischen Grenzgebiet ist die genaue Beschreibung und Dokumentation der Morphe der Hautreaktion und der exakten zeitlichen AblĂ€ufe der Medikamenteneinnahme. Dies erleichtert die Auswahl der adĂ€quaten allergologischen Testverfahren und die Interpretation der Ergebniss
Marker based Thermal-Inertial Localization for Aerial Robots in Obscurant Filled Environments
For robotic inspection tasks in known environments fiducial markers provide a
reliable and low-cost solution for robot localization. However, detection of
such markers relies on the quality of RGB camera data, which degrades
significantly in the presence of visual obscurants such as fog and smoke. The
ability to navigate known environments in the presence of obscurants can be
critical for inspection tasks especially, in the aftermath of a disaster.
Addressing such a scenario, this work proposes a method for the design of
fiducial markers to be used with thermal cameras for the pose estimation of
aerial robots. Our low cost markers are designed to work in the long wave
infrared spectrum, which is not affected by the presence of obscurants, and can
be affixed to any object that has measurable temperature difference with
respect to its surroundings. Furthermore, the estimated pose from the fiducial
markers is fused with inertial measurements in an extended Kalman filter to
remove high frequency noise and error present in the fiducial pose estimates.
The proposed markers and the pose estimation method are experimentally
evaluated in an obscurant filled environment using an aerial robot carrying a
thermal camera.Comment: 10 pages, 5 figures, Published in International Symposium on Visual
Computing 201
Investigating Complex Geometrical Features in LPBF-Produced Parts: A Material-Based Comparison Between Different Titanium Alloys
The Tiâ6Alâ4V (Ti64) alloy is a well-established material to be processed via laser powder bed fusion (LPBF). Recently,
other α + ÎČ titanium alloys are receiving attention, such as Tiâ6Alâ2Snâ4Zrâ6Mo (Ti6246). Their typical industrial fields of
application (aerospace, automotive), often require critical design choices, such as low wall thicknesses and hollow channels.
Thus, a comparative analysis between these two competitor alloys in terms of processability was conducted in this work.
To do so, specific sample designs were developed. The specimens were analyzed in terms of geometrical compliance with
the initial design, porosity, and microstructure. A correlation between the width of the specimens and their porosity, micro-
structure and hardness was found. Overall, both the alloys proved to be well processable, even for very low wall thickness
(300 ÎŒm) and channel diameter (1 mm) values. Nevertheless, the Ti6246 alloy seemed to behave better in specific scenarios.
For instance, some Ti64 specimens provided delamination. The hollow channels proved to be challenging for both materi-
als, mainly due to the high amount of residual powder particles adhered to the upper part of the holes. This works aims at
giving a materials perspective on process-related issues, considering the LPBF-induced defectology and microstructural
variations in these Ti alloys
Parasiten als Ursache von Urtikaria: Helminthen und Protozooen als Auslöser der Nesselsucht?
Zusammenfassung: Die Urtikaria ist eine der hĂ€ufigsten Erkrankungen im dermatologischen Alltag. Die Beschwerden sind fĂŒr die Betroffenen oft sehr einschrĂ€nkend. Es gibt deutliche pathophysiologische und epidemiologische Hinweise, dass Helminthen und Protozoen zwar seltene, aber behandelbare Auslöser von akuter und chronischer Urtikaria sein können. Oftmals fehlt allerdings das Bewusstsein, dass Parasitosen auch in der industrialisierten Gesellschaft, bedingt durch einen steilen Anstieg von Migration und weltweiter ReisetĂ€tigkeit, mit zunehmender PrĂ€valenz vorkommen. Der vorliegende Beitrag stellt die hĂ€ufigsten parasitĂ€ren Ursachen von Urtikaria vor und erlĂ€utert wichtige Aspekte von Anamnese, Klinik, Diagnostik und Therapi
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Exercise addiction and personality: a two-decade systematic review of the empirical literature (1995-2015)
Pressure Dependence of the Magnetic Anisotropy in the "Single-Molecule Magnet" [Mn4O3Br(OAc)3(dbm)3]
The anisotropy splitting in the ground state of the single-molecule magnet
[Mn4O3Br(OAc)3(dbm)3] is studied by inelastic neutron scattering as a function
of hydrostatic pressure. This allows a tuning of the anisotropy and thus the
energy barrier for slow magnetisation relaxation at low temperatures. The value
of the negative axial anisotropy parameter changes from
-0.0627(1) meV at ambient to -0.0603(3) meV at 12 kbar pressure, and in the
same pressure range the height of the energy barrier between up and down spins
is reduced from 1.260(5) meV to 1.213(9) meV. Since the bond is
significantly softer and thus more compressible than the bonds,
pressure induces a tilt of the single ion Mn anisotropy axes, resulting
in the net reduction of the axial cluster anisotropy.Comment: 4 pages, 3 figure
Drug Hypersensitivity Syndrome toCarbamazepine and Human Herpes Virus 6 Infection: Case Reportand Literature Review
Abstract.: We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6). The potential role of HHV-6 regarding the drug-induced hypersensitivity syndrome is discussed and the main clinical features of this potentially fatal adverse drug reaction are highlighte
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