4,564 research outputs found

    Enhanced No-Go Theorem for Quantum Position Verification

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    Based on the instantaneous nonlocal quantum computation (INQC), Buhrman et al. proposed an excellent attack strategy to quantum position verification (QPV) protocols in 2011, and showed that, if the colluding adversaries are allowed to previously share unlimited entangled states, it is impossible to design an unconditionally secure QPV protocol in the previous model. Here, trying to overcome this no-go theorem, we find some assumptions in the INQC attack, which are implicit but essential for the success of this attack, and present three different QPV protocols where these assumptions are not satisfied. We show that for the general adversaries, who execute the attack operations at every common time slot or the time when they detect the arrival of the challenge signals from the verifiers, secure QPV is achievable. This implies practically secure QPV can be obtained even if the adversaries is allowed to share unlimited entanglement previously. Here by "practically" we mean that in a successful attack the adversaries need launch a new round of attack on the coming qubits with extremely high frequency so that none of the possible qubits, which may be sent at random time, will be missed. On the other side, using such Superdense INQC (SINQC) attack, the adversaries can still attack the proposed protocols successfully in theory. The particular attack strategies to our protocols are presented respectively. On this basis, we demonstrate the impossibility of secure QPV with looser assumptions, i.e. the enhanced no-go theorem for QPV.Comment: 19 pages, single column, 3 tables, 6 figure

    Cryptanalysis of a multi-party quantum key agreement protocol with single particles

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    Recently, Sun et al. [Quant Inf Proc DOI: 10.1007/s11128-013-0569-x] presented an efficient multi-party quantum key agreement (QKA) protocol by employing single particles and unitary operations. The aim of this protocol is to fairly and securely negotiate a secret session key among NN parties with a high qubit efficiency. In addition, the authors claimed that no participant can learn anything more than his/her prescribed output in this protocol, i.e., the sub-secret keys of the participants can be kept secret during the protocol. However, here we points out that the sub-secret of a participant in Sun et al.'s protocol can be eavesdropped by the two participants next to him/her. In addition, a certain number of dishonest participants can fully determine the final shared key in this protocol. Finally, we discuss the factors that should be considered when designing a really fair and secure QKA protocol.Comment: 7 page

    Anti-influenza virus effect of aqueous extracts from dandelion

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    <p>Abstract</p> <p>Background</p> <p>Human influenza is a seasonal disease associated with significant morbidity and mortality. Anti-flu Traditional Chinese Medicine (TCM) has played a significant role in fighting the virus pandemic. In TCM, dandelion is a commonly used ingredient in many therapeutic remedies, either alone or in conjunction with other natural substances. Evidence suggests that dandelion is associated with a variety of pharmacological activities. In this study, we evaluated anti-influenza virus activity of an aqueous extract from dandelion, which was tested for in vitro antiviral activity against influenza virus type A, human A/PR/8/34 and WSN (H1N1).</p> <p>Results</p> <p>Results obstained using antiviral assays, minigenome assay and real-time reverse transcription-PCR analysis showed that 0.625-5 mg/ml of dandelion extracts inhibited infections in Madin-Darby canine kidney (MDCK) cells or Human lung adenocarcinoma cell line (A549) of PR8 or WSN viruses, as well as inhibited polymerase activity and reduced virus nucleoprotein (NP) RNA level. The plant extract did not exhibit any apparent negative effects on cell viability, metabolism or proliferation at the effective dose. This result is consistent with the added advantage of lacking any reported complications of the plant's utility in traditional medicine over several centuries.</p> <p>Conclusion</p> <p>The antiviral activity of dandelion extracts indicates that a component or components of these extracts possess anti-influenza virus properties. Mechanisms of reduction of viral growth in MDCK or A549 cells by dandelion involve inhibition on virus replication.</p

    Inhibitory effect of aqueous dandelion extract on HIV-1 replication and reverse transcriptase activity

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    <p>Abstract</p> <p>Background</p> <p>Acquired immunodeficiency syndrome (AIDS), which is caused by the human immunodeficiency virus (HIV), is an immunosuppressive disease that results in life-threatening opportunistic infections. The general problems in current therapy include the constant emergence of drug-resistant HIV strains, adverse side effects and the unavailability of treatments in developing countries. Natural products from herbs with the abilities to inhibit HIV-1 life cycle at different stages, have served as excellent sources of new anti-HIV-1 drugs. In this study, we aimed to investigate the anti-HIV-1 activity of aqueous dandelion extract.</p> <p>Methods</p> <p>The pseudotyped HIV-1 virus has been utilized to explore the anti-HIV-1 activity of dandelion, the level of HIV-1 replication was assessed by the percentage of GFP-positive cells. The inhibitory effect of the dandelion extract on reverse transcriptase activity was assessed by the reverse transcriptase assay kit.</p> <p>Results</p> <p>Compared to control values obtained from cells infected without treatment, the level of HIV-1 replication and reverse transcriptase activity were decreased in a dose-dependent manner. The data suggest that dandelion extract has a potent inhibitory activity against HIV-1 replication and reverse transcriptase activity. The identification of HIV-1 antiviral compounds from <it>Taraxacum officinale </it>should be pursued.</p> <p>Conclusions</p> <p>The dandelion extract showed strong activity against HIV-1 RT and inhibited both the HIV-1 vector and the hybrid-MoMuLV/MoMuSV retrovirus replication. These findings provide additional support for the potential therapeutic efficacy of <it>Taraxacum officinale</it>. Extracts from this plant may be regarded as another starting point for the development of an antiretroviral therapy with fewer side effects.</p
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