5,936 research outputs found
The development of the Canadian Mobile Servicing System Kinematic Simulation Facility
Canada will develop a Mobile Servicing System (MSS) as its contribution to the U.S./International Space Station Freedom. Components of the MSS will include a remote manipulator (SSRMS), a Special Purpose Dexterous Manipulator (SPDM), and a mobile base (MRS). In order to support requirements analysis and the evaluation of operational concepts related to the use of the MSS, a graphics based kinematic simulation/human-computer interface facility has been created. The facility consists of the following elements: (1) A two-dimensional graphics editor allowing the rapid development of virtual control stations; (2) Kinematic simulations of the space station remote manipulators (SSRMS and SPDM), and mobile base; and (3) A three-dimensional graphics model of the space station, MSS, orbiter, and payloads. These software elements combined with state of the art computer graphics hardware provide the capability to prototype MSS workstations, evaluate MSS operational capabilities, and investigate the human-computer interface in an interactive simulation environment. The graphics technology involved in the development and use of this facility is described
Feynman versus Bakamjian-Thomas in Light Front Dynamics
We compare the Bakamjian-Thomas (BT) formulation of relativistic few-body
systems with light front field theories that maintain closer contact with
Feynman diagrams. We find that Feynman diagrams distinguish Melosh rotations
and other kinematical quantities belonging to various composite subsystem
frames that correspond to different loop integrals. The BT formalism knows only
the rest frame of the whole composite system, where everything is evaluated.Comment: 5 page
Neutron Charge Radius: Relativistic Effects and the Foldy Term
The neutron charge radius is studied within a light-front model with
different spin coupling schemes and wave functions. The cancellation of the
contributions from the Foldy term and Dirac form factor to the neutron charge
form factor is verified for large nucleon sizes and it is independent of the
detailed form of quark spin coupling and wave function. For the physical
nucleon our results for the contribution of the Dirac form factor to the
neutron radius are insensitive to the form of the wave function while they
strongly depend on the quark spin coupling scheme.Comment: 12 pages, 5 figures, Latex, Int. J. Mod. Phys.
Investigations of solutions of Einstein's field equations close to lambda-Taub-NUT
We present investigations of a class of solutions of Einstein's field
equations close to the family of lambda-Taub-NUT spacetimes. The studies are
done using a numerical code introduced by the author elsewhere. One of the main
technical complication is due to the S3-topology of the Cauchy surfaces.
Complementing these numerical results with heuristic arguments, we are able to
yield some first insights into the strong cosmic censorship issue and the
conjectures by Belinskii, Khalatnikov, and Lifschitz in this class of
spacetimes. In particular, the current investigations suggest that strong
cosmic censorship holds in this class. We further identify open issues in our
current approach and point to future research projects.Comment: 24 pages, 12 figures, uses psfrag and hyperref; replaced with
published version, only minor corrections of typos and reference
Medium corrections in the formation of light charged particles in heavy ion reactions
Within a microscopic statistical description of heavy ion collisions, we
investigate the effect of the medium on the formation of light clusters. The
dominant medium effects are self-energy corrections and Pauli blocking that
produce the Mott effect for composite particles and enhanced reaction rates in
the collision integrals. Microscopic description of composites in the medium
follows the Dyson equation approach combined with the cluster mean-field
expansion. The resulting effective few-body problem is solved within a properly
modified Alt-Grassberger-Sandhas formalism. The results are incorporated in a
Boltzmann-Uehling-Uhlenbeck simulation for heavy ion collisions. The number and
spectra of light charged particles emerging from a heavy ion collision changes
in a significant manner in effect of the medium modification of production and
absorption processes.Comment: 16 pages, 6 figure
Are tyrosine kinase inhibitors promising for the treatment of systemic sclerosis and other fibrotic diseases?
Tissue fibrosis causes organ failure and death in patients with systemic sclerosis (SSc), but clearly effective anti-fibrotic therapies are not available. The tyrosine kinase inhibitor (TKI) imatinib, which blocks the pro-fibrotic c-Abl kinase and PDGF receptor, is currently evaluated in clinical proof-of-concept trials for the treatment of patients with SSc. In experimental models, imatinib efficiently prevented and reduced tissue fibrosis. First clinical case studies demonstrated anti-fibrotic effects of imatinib in selected patients with SSc and other fibrotic diseases, and observational studies in sclerotic chronic graft-versus-host disease showed promising results. Besides imatinib, the two novel TKIs of c-Abl and PDGF receptor nilotinib and dasatinib have recently proven efficacy in experimental models of SSc. The potential of TKIs of the VEGF receptor (e.g., semaxinib, vatalanib, sutent, and sorafenib) and the EGF receptor (e.g., erlotinib, gefitinib, lapatinib, and canertinib) as anti-fibrotic treatments are also discussed in this review. Prior to clinical use, however, controlled trials need to address efficacy as well as tolerability of TKIs in patients with different fibrotic diseases
In-medium nucleon-nucleon potentials in configuration space
Based on the thermodynamic Green function approach two-nucleon correlations
in nuclear matter at finite temperatures are revisited. To this end, we derive
phase equivalent effective -space potentials that include the effect of the
Pauli blocking at a given temperature and density. These potentials enter into
a Schr\"odinger equation that is the -space representation of the
Galitskii-Feynman equation for two nucleons. We explore the analytical
structure of the equation in the complex -plane by means of Jost functions.
We find that despite the Mott effect the correlation with deuteron quantum
numbers are manifested as antibound states, i.e., as zeros of the Jost function
on the negative imaginary axis of the complex momentum space. The analysis
presented here is also suited for Coulombic systems.Comment: 6 pages, 1 table, 4 figure
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